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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cardiotomsk</journal-id><journal-title-group><journal-title xml:lang="ru">Сибирский журнал клинической и экспериментальной медицины</journal-title><trans-title-group xml:lang="en"><trans-title>Siberian Journal of Clinical and Experimental Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2713-2927</issn><issn pub-type="epub">2713-265X</issn><publisher><publisher-name>TSU publishing</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.29001/2073-8552-2014-29-3-11-20</article-id><article-id custom-type="elpub" pub-id-type="custom">cardiotomsk-101</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL STUDIES</subject></subj-group></article-categories><title-group><article-title>Деформация в продольном направлении и по окружности, ротация, скручивание и раскручивание левого желудочка у пациентов с асимметричной гипертрофией левого желудочка</article-title><trans-title-group xml:lang="en"><trans-title>Global longitudinal and circumferential strain, rotation, twist and untwist of the left ventricle in patients with asymmetric left ventricular hypertrophy</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Павлюкова</surname><given-names>Елена Николаевна</given-names></name><name name-style="western" xml:lang="en"><surname>Pavlyukova</surname><given-names>E. N.</given-names></name></name-alternatives><email xlink:type="simple">pavluk@cardio-tomsk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Терешенкова</surname><given-names>Екатерина Константиновна</given-names></name><name name-style="western" xml:lang="en"><surname>Tereshenkova</surname><given-names>K. K.</given-names></name></name-alternatives><email xlink:type="simple">tek@cardio-tomsk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Карпов</surname><given-names>Ростислав Сергеевич</given-names></name><name name-style="western" xml:lang="en"><surname>Karpov</surname><given-names>R. S.</given-names></name></name-alternatives><email xlink:type="simple">tvk@cardio.tsu.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ "НИИ кардиологии" СО РАМН</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal State Budgetary Institution "Research Institute for Cardiology" of Siberian Branch under the Russian Academy of Medical Sciences</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБУ "НИИ кардиологии" СО РАМН; ГБОУ ВПО "Сибирский государственный медицинский университет" Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal State Budgetary Institution "Research Institute for Cardiology" of Siberian Branch under the Russian Academy of Medical Sciences</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>06</day><month>09</month><year>2016</year></pub-date><volume>29</volume><issue>3</issue><fpage>55</fpage><lpage>62</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Павлюкова Е.Н., Терешенкова Е.К., Карпов Р.С., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Павлюкова Е.Н., Терешенкова Е.К., Карпов Р.С.</copyright-holder><copyright-holder xml:lang="en">Pavlyukova E.N., Tereshenkova K.K., Karpov R.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.sibjcem.ru/jour/article/view/101">https://www.sibjcem.ru/jour/article/view/101</self-uri><abstract><p>Цель: оценить деформацию левого желудочка (ЛЖ) в продольном направлении и по окружности, ротацию, скручивание и раскручивание ЛЖ при асимметричной гипертрофии ЛЖ (ГЛЖ) у пациентов с артериальной гипертонией (АГ) и нормальным уровнем артериального давления (АД), имевших градиент обструкции в выходном тракте ЛЖ 50 мм рт. ст. и более. Анализ выполнен у 31 больного с асимметричной ГЛЖ (у 10 пациентов с АГ и у 21 больного без АГ). Критериями включения в исследование служили наличие градиента обструкции в выходном тракте ЛЖ в покое 50 мм рт. ст. и более, толщина межжелудочковой перегородки (МЖП) 13 мм и более, показатель отношения толщины МЖП к толщине задней стенки ЛЖ более 1,3. В качестве показателя систолической функции ЛЖ оценили показатели глобальной деформации и скорость деформации во время систолы в продольном направлении и по окружности, ротацию, скорость ротации, скручивание ЛЖ. Глобальная деформация ЛЖ в продольном направлении ниже у пациентов в асимметричной ГЛЖ, имевших АГ (-12,317+2,175%), по сравнению с пациентами с нормальным уровнем АД (-15,891+5,145%, р=0,04). Ротация ЛЖ на уровне базальных сегментов выше у пациентов с АГ (-11,164+3,938° vs -5,915+3,492, р=0,01). На уровне верхушки и папиллярных мышц ротация ЛЖ не различалась между пациентами обеих групп. Скорость скручивания выше у пациентов с АГ (129,302+24,973°/с-1 vs 76,836+22,830°/с-1, р=0,008). Таким образом, у больных асимметричной ГЛЖ и АГ глобальная деформация ниже по сравнению с пациентами с нормальным уровнем АД, в то время как ротация на уровне базальных сегментов и скорость скручивания ЛЖ выше у этой категории больных.</p></abstract><trans-abstract xml:lang="en"><p>The aim of the study was to assess left ventricular (LV) global longitudinal Strain/Strain rate, global circumferential Strain/ Strain rate, rotation, twist and untwist in patients with asymmetric LV hypertrophy (LVH) who had gradient of obstruction in the LV outflow tract of 50 mm Hg and more. Thirty one patients with asymmetric LVH and gradient obstruction in the LV outflow were included in the study: 11 patients had arterial hypertension (AH) and 21 patients had normal range of blood pressure values. Criteria for inclusion in this study were gradient of obstruction in Lv outflow of 50 mm Hg and more, intraventricular septum (IVS) thickness of 13 mm and more, and parameters of IVS/LV posterior wall thickness ratio of 1.3 and more. Parameters of global longitudinal Strain/strain rate, global circumferential Strain/Strain rate, rotation, and LV twist were estimated as indicators of the LV systolic function. Left ventricular global longitudinal Strain was significantly lower in patients with AH in comparison with patients with normal range of blood pressures (12.317+2.175% vs. -15.891+5.145%, р=0.04). Left ventricular rotation at the level of basal segments was significantly increased in AH patients (11.164+3.938° vs. -5.915+3.492°, р=0.01) compared with patients with normal blood pressure; rotations at the levels of apex and papillary muscles did not differ between patients’ groups. Twist rate was higher in AH patients (129.302+24.973°/с-1 vs. 76.836+22.830°/с-1, р=0.008). In summary, patients with asymmetrical LVH and AH had lower global Strain as compared with patients with normal blood pressure whereas the LV rotation rate and twist at the level basal segments were higher in these patients.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>асимметричная форма гипертрофии левого желудочка</kwd><kwd>глобальная деформация левого желудочка</kwd><kwd>скручивание</kwd><kwd>раскручивание</kwd><kwd>ротация</kwd><kwd>asymmetric left ventricle hypertrophy</kwd><kwd>global Strain</kwd><kwd>global Strain rate</kwd><kwd>rotation</kwd><kwd>twist</kwd><kwd>untwist</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Алехин М.Н. Ультразвуковые методы оценки деформации миокарда и их клиническое значение // Видар. - М., 2012. - 88 с.</mixed-citation><mixed-citation xml:lang="en">Алехин М.Н. 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