cardiotomskСибирский журнал клинической и экспериментальной медициныSiberian Journal of Clinical and Experimental Medicine2713-29272713-265XTSU publishing10.29001/2073-8552-2020-35-3-67-78cardiotomsk-1043Research ArticleКЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯCLINICAL STUDIESВлияние вскармливания на механику левого желудочка сердца у детей, рожденных с низкой и экстремально низкой массой телаInfluence of feeding on the left ventricular mechanics in children born with low and extremely low body weighthttps://orcid.org/0000-0002-3081-9477ПавлюковаЕ. Н.PavlyukovaE. N.

Павлюкова Елена Николаевна, доктор медицинских наук, профессор, заведующий отделением атеросклероза и хронической ишемической болезни сердца

634012, Томск, ул. Киевская, 111а

Elena N. Pavlyukova, Dr. Sci. (Med.), Professor, Head of the Department of Atherosclerosis and Coronary Artery Disease

111a, Kievskaya str., Tomsk, 634012, Russian Federation

pavluk@cardio-tomsk.ruhttps://orcid.org/0000-0002-5550-5925КолосоваМ. В.KolosovaM. V.

Колосова Марина Владимировна, доктор медицинских наук, профессор кафедры поликлинической педиатрии с курсом пропедевтики детских болезней

634050, Томск, Московский тракт, 2

Marina V. Kolosova, Dr. Sci. (Med.), Professor, Department of Outpatient Pediatrics with Course of Propedeutics of Childhood Diseases

2, Moskovsky tract, Tomsk, 634050, Russian Federation

 

kolosova_mv@inbox.ruНеклюдоваГ. В.NeklyudovaG. A.

Неклюдова Галина Владимировна, аспирант

634012, Томск, ул. Киевская, 111а

Galina V. Neklyudova, Postgraduate Student

111a, Kievskaya str., Tomsk, 634012, Russian Federation

lv-gal@mail.ruhttps://orcid.org/0000-0002-7011-4316КарповР. С.KarpovR. S.

Карпов Ростислав Сергеевич, академик РАН, научный руководитель

634012, Томск, ул. Киевская, 111а

Rostislav S. Karpov, Dr. Sci. (Med.), Professor, Full Member of the Russian Academy of Sciences, Scientific Director

111a, Kievskaya str., Tomsk, 634012, Russian Federation

tvk@cardio-tomsk.ruНаучно-исследовательский институт кардиологии, Томский национальный исследовательский медицинский центр Российской академии наукРоссияCardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of SciencesRussian FederationСибирский государственный медицинский университет Министерства здравоохранения Российской ФедерацииРоссияSiberian State Medical UniversityRussian Federation2020171020203536778Copyright © Павлюкова Е.Н., Колосова М.В., Неклюдова Г.В., Карпов Р.С., 20202020Павлюкова Е.Н., Колосова М.В., Неклюдова Г.В., Карпов Р.С.Pavlyukova E.N., Kolosova M.V., Neklyudova G.A., Karpov R.S.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.sibjcem.ru/jour/article/view/1043Цель

Цель: оценить варианты вращения левого желудочка (ЛЖ) в зависимости от характера вскармливания в течение первого года жизни у детей в возрасте от 1 года до 5 лет, рожденных с очень низкой и экстремально низкой массой тела.

Материал и методы

Материал и методы. В исследование включены 88 детей в возрасте от 1 года до 5 лет, рожденных глубоконедоношенными, с очень низкой и экстремально низкой массой тела. Группу сравнения составили 46 здоровых детей аналогичного возраста, рожденных доношенными. Механика ЛЖ изучена путем оценки вращения на уровне базальных, верхушечных сегментов, папиллярных мышц и скручивания ЛЖ с помощью двухмерной эхокардиографии (ЭхоКГ) и технологии «след пятна» (Speckle Tracking Imaging-2D Strain).

Результаты

Результаты. Установлены различия в частоте выявления типов скручивания ЛЖ в зависимости от характера вскармливания в течение первого года жизни у детей в возрасте от 1 года до 5 лет, рожденных с очень низкой и экстремально низкой массой тела. При естественном вскармливании 1-й («взрослый) тип скручивания ЛЖ зарегистрирован в 75% случаев, 4-й – в 12,5% случаев. При искусственном вскармливании в течение первого года жизни «взрослый» тип скручивания ЛЖ отмечен в 34,38% случаев, 4-й тип скручивания ЛЖ выявлен у 40,63% детей, рожденных глубоконедоношенными. При смешанном вскармливании в течение первого года жизни детей, рожденных с очень низкой и экстремально низкой массой тела, соотношение типов скручивания ЛЖ было следующим: 1-й «взрослый» тип – 40,63%, «детские» типы – 18,75 и 18,75% соответственно, 4-й тип скручивания – 21,88%.

The aim of the study was to evaluate the types of left ventricular (LV) rotation depending on the nature of feeding during the first year of life in oneto five-year-old children born with very low and extremely low body weight.

Material and Methods

Material and Methods. The study included 88 children aged one to five years, born deeply premature with very low and extremely low body weight. The comparison group consisted of 46 healthy children of the same age, born full-term. TheLV mechanics was studied based on the assessment ofLV rotation at the levels of the mitral valve, papillary muscles, and apex andLV twist using two-dimensional echocardiography and two-dimensional speckle-tracking strain imaging.

Results

Results. Differences between the types ofLV twist and the nature of feeding during the first year of life in oneto five-year-old children born with very low and extremely low body weight were identified. In children with natural feeding, the first (“adult”) type ofLV twist was registered in 75% of cases; the fourth type ofLV twist was detected in 12.5% of cases. In children with bottle-feeding during the first year of life, the “adult” type ofLV twist was registered in 34.38% of cases; fourth type ofLV twist was detected in 40.63% of children born deeply premature. In children with mixed feeding during the first year of life, the ratio ofLV twist types was as follows: 40.63% of patients had the first “adult” type; “child” types were present in 18.75% and 18.75% of children, respectively; fourth type of twist was detected in 21.88%.

ротация левого желудочкаскручивание левого желудочкатипы скручивания левого желудочкамеханика левого желудочкадетирожденные с очень низкой массой теладетирожденные с экстремально низкой массой телавскармливание ребенка в течение первого года жизниSpeckle Tracking Imaging-2D StrainKeywords: left ventricular rotationleft ventricular twisttypes of left ventricular twistleft ventricular mechanicschildren born with very low body weightchildren born with extremely low body weightbaby feeding during the first year of lifetwo-dimensional speckle-tracking strain imaging.ReferencesZaitsev K.V., Mezheritskii S.A., Stepanenko N.P., Gostyukhina A.A., Zhukova O.B., Kondrat’eva E.I. et al. Immunological and phenotypic characterization of cell constituents of breast milk. Cell Tiss. Biol. 2016;10(5):410–415. DOI: 10.1134/S1990519X1605014X.Zaitsev K.V., Mezheritskii S.A., Stepanenko N.P., Gostyukhina A.A., Zhukova O.B., Kondrat’eva E.I. et al. 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The authors declare that there are no conflicts of interest present.