cardiotomskСибирский журнал клинической и экспериментальной медициныSiberian Journal of Clinical and Experimental Medicine2713-29272713-265XTSU publishing10.29001/2073-8552-2021-36-1-20-29cardiotomsk-1128Research ArticleОБЗОРЫ И ЛЕКЦИИREVIEWS AND LECTURESСовременные клинико-фундаментальные аспекты в диагностике и лечении пациентов с ишемической кардиомиопатией (обзор)Modern clinical and fundamental aspects in the diagnosis and treatment of patients with ischemic cardiomyopathy (Review)https://orcid.org/0000-0003-1956-0692ШипулинВ. М.ShipulinV. M.

 д-р мед. наук, профессор, главный научный сотрудник; профессор кафедры госпитальной хирургии с курсом сердечно-сосудистой хирургии 

634012, Российская Федерация, Томск, ул. Киевская, 111а

634050, Российская Федерация, Томск, Московский тракт, 2 

 Dr. Sci. (Med.), Professor, Chief Research Scientist; Professor, Department of Hospital Surgery with the Course of Cardiovascular Surgery 

 111a, Kievskaya str., Tomsk, 634012, Russian Federation 

 2, Moskovsky tract, Tomsk, 634050, Russian Federation 

shipulin@cardio-tomsk.ruhttps://orcid.org/0000-0003-0532-8091ПряхинА. С.PryakhinA. S.

 врач сердечно-сосудистый хирург, отделение сердечно-сосудистой хирургии  

634012, Российская Федерация, Томск, ул. Киевская, 111а

 Cardiovascular Surgeon, Department of Cardiovascular Surgery

 111a, Kievskaya str., Tomsk, 634012, Russian Federation 

andrew.prk@mail.ruhttps://orcid.org/0000-0003-4049-8715АндреевС. Л.AndreevS. L.

 канд. мед. наук, старший научный сотрудник, отделение  сердечно-сосудистой хирургии

634012, Российская Федерация, Томск, ул. Киевская, 111а

 Cand. Sci. (Med.), Senior Research Scientist, Department of Cardiovascular Surgery

 111a, Kievskaya str., Tomsk, 634012, Russian Federation 

anselen@rambler.ruhttps://orcid.org/0000-0001-9887-8214ШипулинВ. В.ShipulinV. V.

 аспирант, лаборатория радионуклидных методов  исследования 

634012, Российская Федерация, Томск, ул. Киевская, 111а

 Postgraduate Student, Department of Nuclear Medicine

 111a, Kievskaya str., Tomsk, 634012, Russian Federation 

shipartphoto@gmail.comhttps://orcid.org/0000-0003-3468-6154ЧумаковаС. П.ChumakovaS. P.

 д-р мед. наук, профессор кафедры патофизиологии

 634050, Российская Федерация, Томск, Московский тракт, 2 

 Dr. Sci. (Med.), Professor, Department of Pathophysiology

 2, Moskovsky tract, Tomsk, 634050, Russian Federation 

chumakova_s@mail.ruhttps://orcid.org/0000-0001-8573-5695РябоваТ. Р.RyabovaT. R.

 канд. мед. наук, старший научный сотрудник, отделение функциональной и лабораторной диагностики

634012, Российская Федерация, Томск, ул. Киевская, 111а

 Cand. Sci. (Med.), Senior Research Scientist, Department of Functional and Laboratory Diagnostics

 111a, Kievskaya str., Tomsk, 634012, Russian Federation 

rtrtom@mail.ruhttps://orcid.org/0000-0002-8284-6864СтельмашенкоА. И.StelmashenkoA. I.

 аспирант, кафедра морфологии и общей патологии

 634050, Российская Федерация, Томск, Московский тракт, 2 

 Postgraduate Student, Department of Morphology and General Pathology

 2, Moskovsky tract, Tomsk, 634050, Russian Federation 

astella1995@gmail.comhttps://orcid.org/0000-0002-0037-2205БеляеваС. А.BelyaevaS. A.

 лаборант, кафедра морфологии и общей патологии 

 634050, Российская Федерация, Томск, Московский тракт, 2 

 Laboratory Assistant, Department of Morphology and General Pathology

 2, Moskovsky tract, Tomsk, 634050, Russian Federation 

sonchaaaa@gmail.comhttps://orcid.org/0000-0002-7553-001XЛеликЕ. В.LelikE. V.

 врач-кардиолог, отделение сердечно-сосудистой хирургии 

634012, Российская Федерация, Томск, ул. Киевская, 111а

 Cardiologist, Department of Cardiovascular Surgery

 111a, Kievskaya str., Tomsk, 634012, Russian Federation 

eva00@list.ruНаучно-исследовательский институт кардиологии, Томский национальный исследовательский медицинский центр Российской академии наук; Сибирский государственный медицинский университет Министерства здравоохранения Российской ФедерацииРоссияCardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences; Siberian State Medical UniversityRussian FederationНаучно-исследовательский институт кардиологии, Томский национальный исследовательский медицинский центр Российской академии наукРоссияCardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences;  Russian FederationНаучно-исследовательский институт кардиологии, Томский национальный исследовательский медицинский центр Российской академии наукРоссияCardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of SciencesRussian FederationНаучно-исследовательский институт кардиологии, Томский национальный исследовательский медицинский центр Российской академии наукРоссияCardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences Russian FederationСибирский государственный медицинский университет Министерства здравоохранения Российской ФедерацииРоссияSiberian State Medical University Russian FederationСибирский государственный медицинский университет Министерства здравоохранения Российской ФедерацииРоссияSiberian State Medical UniversityRussian FederationНаучно-исследовательский институт кардиологии, Томский национальный исследовательский медицинский центр Российской академии наукРоссияCardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences Russian Federation2021010420213612029Copyright © Шипулин В.М., Пряхин А.С., Андреев С.Л., Шипулин В.В., Чумакова С.П., Рябова Т.Р., Стельмашенко А.И., Беляева С.А., Лелик Е.В., 20212021Шипулин В.М., Пряхин А.С., Андреев С.Л., Шипулин В.В., Чумакова С.П., Рябова Т.Р., Стельмашенко А.И., Беляева С.А., Лелик Е.В.Shipulin V.M., Pryakhin A.S., Andreev S.L., Shipulin V.V., Chumakova S.P., Ryabova T.R., Stelmashenko A.I., Belyaeva S.A., Lelik E.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.sibjcem.ru/jour/article/view/1128

 В данной работе обсуждаются современные клинико-фундаментальные аспекты диагностики и лечения пациентов с ишемической кардиомиопатией (ИКМП). Рассматриваются патофизиологические, морфологические и  иммуногистохимические аспекты ремоделирования левого  желудочка (ЛЖ) при ИКМП. Приводится подробная  характеристика и показана роль методов оценки  функциональных резервов миокарда при ИКМП.  Акцентировано внимание на методиках хирургического лечения при ИКМП. Статья рассчитана на кардиологов,  терапевтов, кардиохирургов.  

 The article discusses the modern clinical and fundamental aspects of the diagnosis and treatment of patients with ischemic cardiomyopathy (ICMP). The pathophysiological, morphological, and immunohistochemical aspects of left ventricular remodeling in ICMP are reviewed. A detailed description is given and the role of methods for assessment of myocardial functional reserves in ICMP is shown. The attention is focused on the methods of surgical treatment for ICMP. The article is intended for cardiologists, therapists, and cardiac surgeons. 

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The authors declare that there are no conflicts of interest present.