cardiotomskСибирский журнал клинической и экспериментальной медициныSiberian Journal of Clinical and Experimental Medicine2713-29272713-265XTSU publishing10.29001/2073-8552-2021-36-1-30-37cardiotomsk-1129Research ArticleОБЗОРЫ И ЛЕКЦИИREVIEWS AND LECTURESИсходы применения различных конструкций каротидных стентовOutcomes of using various designs of carotid stentshttps://orcid.org/0000-0002-7418-3298ОсиповаО. С.OsipovaO. S.

 аспирант, стажер-исследователь, центр сосудистой и гибридной хирургии 

630055, Российская Федерация, Новосибирск, ул. Речкуновская, 15

 Postgraduate Student, Center for Vascular and Hybrid Surgery

 15, Rechkunovskaya str., Novosibirsk, 630055, Russian Federation 

osipova_o@meshalkin.ruhttps://orcid.org/0000-0002-6911-4650ПоповаИ. В.PopovaI. V.

 канд. мед. наук, научный сотрудник, центр сосудистой и гибридной хирургии 

630055, Российская Федерация, Новосибирск, ул. Речкуновская, 15

 Cand. Sci. (Med.), Research Scientist, Center for Vascular and Hybrid Surgery 

 15, Rechkunovskaya str., Novosibirsk, 630055, Russian Federation 

i_popova@meshalkin.ruhttps://orcid.org/0000-0002-4913-614XСтародубцевВ. Б.StarodubtsevV. B.

 канд. мед. наук, ведущий научный сотрудник, центр сосудистой и гибридной хирургии

630055, Российская Федерация, Новосибирск, ул. Речкуновская, 15

 Cand. Sci. (Med.), Leading Research Scientist, Center for Vascular and Hybrid Surgery 

 15, Rechkunovskaya str., Novosibirsk, 630055, Russian Federation 

v_starodubtsev@meshalkin.ruhttps://orcid.org/0000-0002-6875-5122БугуровС. В.BugurovS. V.

 врач по рентген-эндоваскулярным диагностике и лечению, младший научный сотрудник, кардиохирургическоеотделение сосудистой патологии и гибридных технологий, центр сосудистой и гибридной хирургии

630055, Российская Федерация, Новосибирск, ул. Речкуновская, 15

 Interventional Cardiologist, Junior Research Scientist, Department of Vascular Pathology and Hybrid Technologies, Center for Vascular and Hybrid Surgery 

 15, Rechkunovskaya str., Novosibirsk, 630055, Russian Federation 

bugurov_s@meshalkin.ruhttps://orcid.org/0000-0002-6094-4607ЧебанА. В.ChebanA. V.

 врач сердечно-сосудистый хирург, младший научный сотрудник, кардиохирургическое отделение сосудистой патологии и гибридных технологий, центр сосудистой и гибридной хирургии 

630055, Российская Федерация, Новосибирск, ул. Речкуновская, 15

 Cardiovascular Surgeon, Junior Research Scientist, Department of Vascular Pathology and Hybrid Technologies, Center for Vascular and Hybrid Surgery 

 15, Rechkunovskaya str., Novosibirsk, 630055, Russian Federation 

cheban_a@meshalkin.ruhttps://orcid.org/0000-0001-6914-334XКарпенкоА. А.KarpenkoA. A.

 д-р мед. наук, профессор, руководитель центра сосудистой и гибридной хирургии

630055, Российская Федерация, Новосибирск, ул. Речкуновская, 15 

 Dr. Sci. (Med.), Professor, Head of the Center for Vascular and Hybrid Surgery 

15, Rechkunovskaya str., Novosibirsk, 630055, Russian Federation

a_karpenko@meshalkin.ruНациональный медицинский исследовательский центр имени академика Е.Н. Мешалкина Министерства здравоохранения Российской ФедерацииРоссияMeshalkin National Medical Research Center Russian Federation2021010420213613037Copyright © Осипова О.С., Попова И.В., Стародубцев В.Б., Бугуров С.В., Чебан А.В., Карпенко А.А., 20212021Осипова О.С., Попова И.В., Стародубцев В.Б., Бугуров С.В., Чебан А.В., Карпенко А.А.Osipova O.S., Popova I.V., Starodubtsev V.B., Bugurov S.V., Cheban A.V., Karpenko A.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.sibjcem.ru/jour/article/view/1129

 Предполагается, что характеристики устройства, включая конструкцию стента, могут быть предикторами неблагоприятных исходов после стентирования сонной артерии (ССА). На рынке появляются новые конструкции стентов, производители которых заявляют о способности предотвращать интра- и послеоперационные эмболии. В статье представлен обзор клинических исследований,  сравнивающих частоту рестоноза и ишемических  осложнений различных конструкций каротидных стентов.  Теоретически стенты с закрытыми ячейками и двухслойные  стенты в большей степени предотвращают  постимплантационные эмболии в головной мозг, чем стенты с открытыми ячейками. Однако клиническая значимость этого явления не доказана, и данные о влиянии различных типов каротидных стентов на результаты стентирования остаются противоречивыми. Во многих случаях выбор стента диктуется анатомией целевого сосуда. Возможно, результаты новых рандомизированных контролируемых исследований (РКИ) смогут прояснить клиническую значимость различных конструкций стентов.  

 It is assumed that the characteristics of stents including design of device may be predictors of adverse outcomes in carotid stenting. New stent designs enter the market and the stent manufacturers declare their ability to prevent periprocedural and postprocedural embolisms. The article provides an overview of clinical trials comparing the incidence rates of restenosis and ischemic complications in carotid artery stenting with various stent designs.  In theory, the closed-cell stents and doublelayer stents are superior to the  open-cell stents in preventing the postprocedural cerebral embolisms.  However, the clinical significance of this phenomenon has not been proven, and the data on the effect of various carotid stent types on the stenting results remain controversial. In many cases, the choice of stent depends on the anatomy of the target vessel. The results of new randomized controlled clinical trials may clarify the clinical relevance of various stent designs.  

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The authors declare that there are no conflicts of interest present.