cardiotomskСибирский журнал клинической и экспериментальной медициныSiberian Journal of Clinical and Experimental Medicine2713-29272713-265XTSU publishing10.29001/2073-8552-2021-36-4-29-36cardiotomsk-1280Research ArticleОБЗОРЫ И ЛЕКЦИИREVIEWS AND LECTURESЭтические проблемы генетического тестирования при наследственных заболеваниях сердечно-сосудистой системыEthical problems of genetic testing for hereditary cardiovascular diseaseshttps://orcid.org/0000-0002-5337-1775БостановаФ. М.BostanovaF. M.

 клинический ординатор

 115522, Российская Федерация, Москва, ул. Москворечье, 1 

 Medical Resident

 1, Moskvorechye str., Moscow, 115522, Russian Federation 

fatima1893@mail.ruhttps://orcid.org/0000-0002-7246-5144ИжевскаяВ. Л.IzhevskayaV. L.

 д-р мед. наук, заместитель директора по научной работе, председатель Российского общества медицинских генетиков

 115522, Российская Федерация, Москва, ул. Москворечье, 1 

 Dr. Sci. (Med.), Deputy Director for Science; President of the Russian Society ofMedical Genetics 

 1, Moskvorechye str., Moscow, 115522, Russian Federation 

izhevskaya@med-gen.ruМедико-генетический научный центр имени академика Н.П. БочковаРоссияResearch Centre for Medical Genetics Russian FederationМедико-генетический научный центр имени академика Н.П. БочковаРоссияResearch Centre for Medical GeneticsRussian Federation2021010120223642936Copyright © Бостанова Ф.М., Ижевская В.Л., 20222022Бостанова Ф.М., Ижевская В.Л.Bostanova F.M., Izhevskaya V.L.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.sibjcem.ru/jour/article/view/1280

 В обзоре представлены отечественные и зарубежные данные, отражающие особенности медико-генетического  консультирования и прогностического тестирования  пациентов с наследственными заболеваниями сердечно-сосудистой системы. Освещены этические проблемы геномного тестирования, особенно вторичных (случайных)  находок, каскадного скрининга, обследования детей и  подростков, посмертного генетического тестирования.  Особое внимание уделено психосоциальному воздействию  генетического тестирования. 

 Data on the features of genetic counseling and predictive testing in patients with hereditary cardiovascular diseases are presented in the review. The ethical problems of genomic testing especially in regard to secondary (incidental) fi ndings, cascade screening, examination of children and adolescents, and postmortem genetic testing are discussed. Particular attention is paid to the psychosocial impact of genetic testing. 

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The authors declare that there are no conflicts of interest present.