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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cardiotomsk</journal-id><journal-title-group><journal-title xml:lang="ru">Сибирский журнал клинической и экспериментальной медицины</journal-title><trans-title-group xml:lang="en"><trans-title>Siberian Journal of Clinical and Experimental Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2713-2927</issn><issn pub-type="epub">2713-265X</issn><publisher><publisher-name>TSU publishing</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.29001/2073-8552-2021-36-4-87-95</article-id><article-id custom-type="elpub" pub-id-type="custom">cardiotomsk-1358</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL STUDIES</subject></subj-group></article-categories><title-group><article-title>Непосредственные результаты хирургической реваскуляризации миокарда с использованием аутоартериальных кондуитов в условиях искусственного кровообращения и на работающем сердце</article-title><trans-title-group xml:lang="en"><trans-title>Immediate results of off-pump versus on-pump coronary artery bypass grafting using autoarterial conduits in situ and Y-graft configurations</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4096-0375</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мурадов</surname><given-names>А. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Muradov</surname><given-names>A. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач сердечно-сосудистый хирург кардиохирургического отделения № 1, </p><p>660020, Красноярск, ул. Караульная, 45</p></bio><bio xml:lang="en"><p>Cardiovascular Surgeon, Cardiovascular Department No. 1,</p><p>45, Karaulnaya str., Krasnoyarsk, 660020</p></bio><email xlink:type="simple">ranjer1986@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5170-4978</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Эфендиев</surname><given-names>В. У.</given-names></name><name name-style="western" xml:lang="en"><surname>Efendiev</surname><given-names>V. U.</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. мед. наук, врач сердечно-сосудистый хирург кардиохирургического отделения № 1, </p><p>660020, Красноярск, ул. Караульная, 45</p></bio><bio xml:lang="en"><p>Cand. Sci. (Med.), Cardiovascular Surgeon, Cardiovascular Department No. 1,</p><p>45, Karaulnaya str., Krasnoyarsk, 660020</p></bio><email xlink:type="simple">vidadiue@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4184-742X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Андин</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Andin</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. мед. наук, врач сердечно-сосудистый хирург, заведующий кардиохирургическим отделением № 1,</p><p>660020, Красноярск, ул. Караульная, 45</p></bio><bio xml:lang="en"><p>Cand. Sci. (Med.), Cardiovascular Surgeon, Head of Cardiovascular Department No. 1,</p><p>45, Karaulnaya str., Krasnoyarsk, 660020</p></bio><email xlink:type="simple">Andin.AV@krascor.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9003-4818</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дробот</surname><given-names>Д. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Drobot</surname><given-names>D. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук, профессор кафедры и клиники сердечно-сосудистой хирургии, Институт последипломного образования, 660022, Красноярск, ул. Партизана Железняка, 1;</p><p>660020, Красноярск, ул. Караульная, 45</p><p> </p></bio><bio xml:lang="en"><p>Dr. Sci. (Med.), Professor, Department and Clinic of Cardiovascular Surgery, Institute of Postgraduate Education, 1, Partizana Zheleznyaka str., Krasnoyarsk, 660022;</p><p>45, Karaulnaya str., Krasnoyarsk, 660020</p></bio><email xlink:type="simple">DrobotDB@krascor.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7743-8770</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сакович</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Sakovich</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p> д-р мед. наук, профессор, главный врач, 660020, Красноярск, ул. Караульная, 45;</p><p>заведующий кафедрой и клиники сердечно-сосудистой хирургии, Институт последипломногообразования, 660022, Красноярск, ул. Партизана Железняка, 1</p></bio><bio xml:lang="en"><p>Dr. Sci. (Med.), Professor, Chief Physician, 45, Karaulnaya str., Krasnoyarsk, 660020;</p><p>Head of the Department and Clinic of Cardiovascular Surgery, 1, Partizana Zheleznyaka str., Krasnoyarsk, 660022</p></bio><email xlink:type="simple">SakovichVA@krascor.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральный центр сердечно-сосудистой хирургии Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal Center for Cardiovascular Surgery</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Федеральный центр сердечно-сосудистой хирургии Министерства здравоохранения Российской Федерации;&#13;
Красноярский государственный медицинский университет имени профессора В.Ф. Войно-Ясенецкого Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Krasnoyarsk State Medical University named after Professor V.F. Voyno-Yasenetsky;&#13;
Federal Center for Cardiovascular Surgery</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Федеральный центр сердечно-сосудистой хирургии Министерства здравоохранения Российской Федерации;&#13;
Красноярский государственный медицинский университет имени профессора В.Ф. Войно-Ясенецкого Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal Center for Cardiovascular Surgery;&#13;
Krasnoyarsk State Medical University named after Professor V.F. Voyno-Yasenetsky</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>07</day><month>04</month><year>2022</year></pub-date><volume>37</volume><issue>1</issue><fpage>87</fpage><lpage>95</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Мурадов А.Г., Эфендиев В.У., Андин А.В., Дробот Д.Б., Сакович В.А., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Мурадов А.Г., Эфендиев В.У., Андин А.В., Дробот Д.Б., Сакович В.А.</copyright-holder><copyright-holder xml:lang="en">Muradov A.G., Efendiev V.U., Andin A.V., Drobot D.B., Sakovich V.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.sibjcem.ru/jour/article/view/1358">https://www.sibjcem.ru/jour/article/view/1358</self-uri><abstract><sec><title>Цель</title><p>Цель: оценить ближайшие результаты хирургической реваскуляризации миокарда с использованием аутоартериальных кондуитов в условиях искусственного кровообращения (ИК) и на работающем сердце (РС).</p></sec><sec><title>Материал и методы</title><p>Материал и методы. С января 2018 г. по сентябрь 2021 г. в отделении № 1 ФЦССХ (г. Красноярск) проведено 178 операций коронарного шунтирования (КШ) с использованием аутоартериальных кондуитов: 88 пациентам операция выполнялась на РС (группа 1), 90 пациентам в условиях ИК (группа 2). В обеих группах большинство пациентов были мужского пола: 76 (86,3%) и 75 (83,3%), p = 0,287. Пациенты были сопоставимы по возрасту: 61,6 ± 7,7 и 60,2 ± 7,5 лет (p = 0,237), индексу массы тела: 30,9 ± 5,7 и 29,8 ± 5 кг/м² (p = 0,18), сопутствующему сахарному диабету: 30 (34%) и 19 (21,1%), p = 0,052. В группе 1 было достоверно больше пациентов с гемодинамически значимым поражением брахиоцефальных артерий: 27 (30,7%) против 13 (14,4%), p = 0,009; кальцинозом восходящего отдела аорты: 24 (27,3%) против 11 (12,2%), p = 0,011. Количество гемодинамически значимых пораженных коронарных артерий (КА) между группами не различалось: 2,6 ± 0,7 против 2,5 ± 0,5 (p = 0,393).</p></sec><sec><title>Результаты</title><p>Результаты. В обеих группах обе внутренние грудные артерии (ВГА) использовались in situ или в виде Y-графт в зависимости от числа дистальных анастомозов. Госпитальная летальность составила 2 пациента (2,2%), оба из группы 2 (p = 0,161). Группы были сопоставимы по числу дистальных анастомозов: 2,7 ± 0,7 и 2,7 ± 0,6 (p = 0,532), частоте развития острого периоперационного инфаркта миокарда: 1 (1,1%) и 1 (1,1%), p = 0,987, неврологическим осложнениям: 1 (1,1%) и 2 (2,2%), p = 0,576. Глубокая стернальная инфекция отсутствовала в обеих группах.</p></sec><sec><title>Выводы</title><p>Выводы. Аутоартериальное КШ – эффективный метод реваскуляризации миокарда как в условиях РС, так и в условиях ИК. Данную методику необходимо рассматривать как операцию выбора для пациентов с множественным поражением КА. Выполнение операций в условиях ИК не влияет на увеличение числа кардиоцеребральных событий в послеоперационном периоде. </p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Aim</title><p>Aim. To compare the immediate results of off-pump versus on-pump coronary artery bypass grafting (CABG) using autoarterial conduits.</p></sec><sec><title>Material and Methods</title><p>Material and Methods. From January 2018 to September 2021, 178 coronary artery bypass grafting operations using autoarterial conduits were performed in the Department No. 1 of the Federal Center for Cardiovascular Surgery (Krasnoyarsk). The operation was performed on a beating heart in 88 patients (group 1) and using cardiopulmonary bypass in 90 patients (group 2). The majority of patients were males in both groups: 76 (86.3%) and 75 (83.3%) patients (p = 0.287). The patients were comparable in age (61.6 ± 7.7 and 60.2 ± 7.5 years, p = 0.237), body mass index (30.9 ± 5.7 and 29.8 ± 5, p = 0.18), and the presence of concomitant diabetes mellitus (30 (34%) and 19 (21.1%), p = 0.052). There were significantly more patients with hemodynamically significant lesions of the brachiocephalic arteries in group 1 (27 (30.7%) versus 13 (14.4%), p = 0.009) and calcification of the ascending aorta (24 (27.3%) versus 11 (12.2%), p = 0.011). The number of hemodynamically significant affected coronary arteries did not differ between the groups: 2.6 ± 0.7 versus 2.5 ± 0.5 (p = 0.393).</p></sec><sec><title>Results</title><p>Results. Both internal thoracic arteries were used in situ or in the form of Y-grafts in both groups depending on the number of distal anastomoses. Hospital mortality was 2 patients (2.2%), both from group 2 (p = 0.161). The groups were comparable in the number of distal anastomoses (2.7 ± 0.7 and 2.7 ± 0.6, p = 0.532), the incidence of acute perioperative myocardial infarction (1 (1.1%) and 1 (1.1%), p = 0.987), neurological complications (1 (1.1%) and 2 (2.2%), p = 0.576), and bleeding requiring resternotomy (1 (1.1%) and 3 (3.3%), p = 0.325). Deep sternal wood infection was absent in both groups.</p></sec><sec><title>Conclusion</title><p>Conclusion. Autoarterial coronary artery bypass grafting is an effective method of myocardial revascularization in both the beating heart surgery and in cardiopulmonary bypass conditions. This method should be considered an operation of choice for patients with multiple coronary artery disease. The performance of operations in the conditions of cardiopulmonary bypass does not affect the increase in the number of cardiocerebral events in the postoperative period. </p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>коронарное шунтирование</kwd><kwd>искусственное кровообращение</kwd><kwd>работающее сердце</kwd><kwd>аутоартериальные кондуиты</kwd></kwd-group><kwd-group xml:lang="en"><kwd>coronary artery bypass grafting</kwd><kwd>cardiopulmonary bypass</kwd><kwd>beating heart</kwd><kwd>autoarterial conduits.</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Жмуров Д.В., Парфентева М.А., Семенова Ю.В. Ишемическая болезнь сердца. Colloquium Journal. 2020;29(81):32–37. DOI: 10.24412/2520-2480-2020-2981-32-37.</mixed-citation><mixed-citation xml:lang="en">Gmurov D.V., Parfenteva M.A., Semenova Y.V. Coronary heart disease. 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