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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cardiotomsk</journal-id><journal-title-group><journal-title xml:lang="ru">Сибирский журнал клинической и экспериментальной медицины</journal-title><trans-title-group xml:lang="en"><trans-title>Siberian Journal of Clinical and Experimental Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2713-2927</issn><issn pub-type="epub">2713-265X</issn><publisher><publisher-name>TSU publishing</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.29001/2073-8552-2022-37-1-123-128</article-id><article-id custom-type="elpub" pub-id-type="custom">cardiotomsk-1362</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL STUDIES</subject></subj-group></article-categories><title-group><article-title>Сравнительная оценка качества жизни пациентов со старческой астенией и перенесенным COVID-19 через 3 и 6 месяцев после выписки из стационара</article-title><trans-title-group xml:lang="en"><trans-title>Comparative characteristics of the quality of life in patients with senile asthenia and history of COVID-19 three and six months after discharge from the hospital</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0542-4040</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Петров</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Petrov</surname><given-names>M. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>аспирант кафедры «Внутренние болезни»,</p><p>440026, Пенза, ул. Красная, 40</p></bio><bio xml:lang="en"><p>Post-Graduate Student, Department of Internal Diseases, </p><p>40, Krasnaya str., Penza, 440026</p></bio><email xlink:type="simple">mikh.petrov1@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7250-0504</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Белугина</surname><given-names>Т. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Belugina</surname><given-names>T. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. мед. наук, доцент кафедры «Внутренние болезни», </p><p> </p></bio><bio xml:lang="en"><p>Cand. Sci. (Med.), Associate Professor, Department of Internal Diseases, </p><p>40, Krasnaya str., Penza, 440026</p></bio><email xlink:type="simple">beluginatn@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6568-0305</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бурмистрова</surname><given-names>Л. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Burmistrova</surname><given-names>L. F.</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. мед. наук, доцент кафедры «Внутренние болезни», </p><p> </p></bio><bio xml:lang="en"><p>Cand. Sci. (Med.), Associate Professor, Department of Internal Diseases,</p><p>40, Krasnaya str., Penza, 440026</p></bio><email xlink:type="simple">lamax-69@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8428-5346</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Грачева</surname><given-names>Ю. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Gracheva</surname><given-names>J. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. мед. наук, доцент кафедры «Внутренние болезни», </p><p> </p></bio><bio xml:lang="en"><p>Cand. Sci. (Med.), Associate Professor, Department of Internal Diseases,</p><p>40, Krasnaya str., Penza, 440026</p></bio><email xlink:type="simple">y.gracheva@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Пензенский государственный университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Penza State University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>09</day><month>04</month><year>2022</year></pub-date><volume>37</volume><issue>1</issue><fpage>123</fpage><lpage>128</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Петров М.В., Белугина Т.Н., Бурмистрова Л.Ф., Грачева Ю.Н., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Петров М.В., Белугина Т.Н., Бурмистрова Л.Ф., Грачева Ю.Н.</copyright-holder><copyright-holder xml:lang="en">Petrov M.V., Belugina T.N., Burmistrova L.F., Gracheva J.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.sibjcem.ru/jour/article/view/1362">https://www.sibjcem.ru/jour/article/view/1362</self-uri><abstract><sec><title>Актуальность</title><p>Актуальность. Пациенты с перенесенным COVID-19 и синдромом старческой астении (СА) характеризуются крайне высокой коморбидностью, гетерогенностью, атипичным течением заболевания, а также большим количеством осложнений. Высокая распространенность этой категории больных и отсутствие подобных исследований сподвигли на проведение данной работы.</p></sec><sec><title>Цель</title><p>Цель: комплексная оценка качества жизни (КЖ) пациентов с перенесенным COVID-19 и СА.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. В 1-ю группу включены 37 пациентов с СА и перенесенным COVID-19 через 3 мес. после выписки из стационара, во 2-ю – 35 пациентов с СА и перенесенным COVID-19 через 6 мес. после выписки из стационара, контрольную группу составили 34 пациента старше 65 лет с СА, не перенесшие COVID-19. Оценку КЖ осуществляли по опроснику SF-36.</p></sec><sec><title>Результаты</title><p>Результаты. Через 3 мес. после выписки из стационара отмечалось снижение абсолютно всех показателей физического и психосоциального аспектов здоровья; через 6 мес. более выраженным было снижение шкал физического статуса (физическое функционирование (PF), ролевое физическое функционирование (RP), общее состояние здоровья (GH)) и психического здоровья (MH). В женской популяции регистрировалось более низкое КЖ по большинству шкал (PF, RP, GH, MH, ролевое эмоциональное функционирование (RE)) независимо от времени, прошедшего с момента выписки из стационара, а также более высокая частота депрессии по сравнению с мужчинами.</p></sec><sec><title>Выводы</title><p>Выводы. Все показатели КЖ пациентов с СА и перенесенным COVID-19 снижаются в первые 3 мес. после выписки из стационара. При этом через 6 мес. наиболее выражено снижение физического статуса, тогда как показатели психической сферы снижены только по шкале MH. Через 3 мес., как и через 6 мес. после выписки из стационара, КЖ в мужской популяции выше по сравнению с женской по одинаковым оценочным шкалам (PF, RP, GH, MH, RE). Лучшие показатели по шкале интенсивности боли (BP) для мужчин характерны только для 1-й группы пациентов, тогда как по данным социального функционирования (SF) и MH не было отмечено статистически достоверной разницы. В женской популяции регистрировалась более высокая частота депрессии, при этом распространенность тревожных состояний через 3 мес. после выписки была выше, чем через 6 мес. </p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Background</title><p>Background. Patients with COVID-19 and senile asthenia syndrome (SA) are characterized by extremely high comorbidity, heterogeneity, atypical course of the disease, and large number of complications. We carried out a comprehensive assessment of the quality of life (QOL) in patients with COVID-19 and SA considering the high prevalence of this category of patients and the absence of such studies.</p></sec><sec><title>Material and Methods</title><p>Material and Methods. Group 1 included 37 patients with SA and history of COVID-19 three months after discharge from the hospital. Group 2 included 35 patients with CA and history of COVID-19 six months later. Control group comprised 34 patients with SA aged over 65 years who did not have COVID-19. The assessment of QOL was carried out according to the SF-36 questionnaire.</p></sec><sec><title>Results</title><p>Results. There was a decrease in absolutely all indicators of physical and psychosocial aspects of health three months after discharge from the hospital. There was a more pronounced decrease in the scales of physical functioning (PF), role-physical functioning (RP), general health (GH), and mental health (MH) after six months. There was a lower QOL in female population according to most scales (PF, RP, GH, MH, and role-emotional functioning (RE)) regardless of the time from the moment of discharge from the hospital, and a higher incidence of depression compared to men.</p></sec><sec><title>Conclusions</title><p>Conclusions. All QOL indicators of patients with SA and history of COVID-19 decreased within the first three months after discharge from the hospital. At the same time, after six months, a decrease in physical status was most pronounced, while the indicators of mental sphere reduced only according to the MH scale. At three and six months after discharge, the quality of life in the male population was higher than in the female population according to the same evaluation scales (PF, RP, GH, MH, and RE). The best indicators of pain scale in men were characteristic only for the first group of patients, whereas there was no statistically significant difference according to the social functioning and MH data. There was a higher incidence of depression in the female population, while the prevalence of anxiety was higher at three months after discharge than after six months. </p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>качество жизни</kwd><kwd>COVID-19</kwd><kwd>старческая астения</kwd></kwd-group><kwd-group xml:lang="en"><kwd>quality of life</kwd><kwd>COVID-19</kwd><kwd>senile asthenia</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Akin L., Gözel M.G. Understanding dynamics of pandemics. Turk. J. Med. Sci. 2020;50(SI-1):515–519. DOI: 10.3906/sag-2004-133.</mixed-citation><mixed-citation xml:lang="en">Akin L., Gözel M.G. Understanding dynamics of pandemics. 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