cardiotomskСибирский журнал клинической и экспериментальной медициныSiberian Journal of Clinical and Experimental Medicine2713-29272713-265XTSU publishing10.29001/2073-8552-2022-37-3-49-55cardiotomsk-1502Research ArticleОБЗОРЫ И ЛЕКЦИИREVIEWS AND LECTURESДелирий у больного инфарктом миокардаDelirium in a patient with myocardial infarctionhttps://orcid.org/0000-0001-5152-2106ПантелеевО. О.PanteleevO. O.

Пантелеев Олег Олегович, младший научный сотрудник, врач анестезиолог-реаниматолог, отделение неотложной кардиологии; ассистент кафедры кардиологии ФПК и ППС

634012, Томск, ул. Киевская, 111а

Oleg O. Panteleev, Junior Research Scientist, Department of Emergency Cardiology; Assistant Professor, Cardiology Department, Continuous Medical Education Faculty

111a, Kievskaya str., Tomsk, 634012

panteleev.o.o@yandex.ruhttps://orcid.org/0000-0002-4358-7329РябовВ. В.RyabovV. V.

Рябов Вячеслав Валерьевич, д-р мед. наук, заместитель директора по научной и лечебной работе, заведующий отделением неотложной кардиологии; заведующий кафедрой кардиологии ФПК и ППС; ведущий научный сотрудник, лаборатория трансляционной клеточной и молекулярной биомедицины

634012, Томск, ул. Киевская, 111а

Vyacheslav V. Ryabov, Dr. Sci. (Med.), Deputy Director for Research and Clinical Services, Head of Department of Emergency Cardiology, Cardiology Research Institute; Head of Cardiology Department, Continuous Medical Education Faculty; Leading Research Scientist, Laboratory of Translational Cell and Molecular Biomedicine

111a, Kievskaya str., Tomsk, 634012

rvvt@cardio-tomsk.ruНаучно-исследовательский институт кардиологии, Томский национальный исследовательский медицинский центр Российской академии наук; Сибирский государственный медицинский университет Министерства здравоохранения Российской ФедерацииРоссияCardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences; Siberian State Medical UniversityRussian FederationНаучно-исследовательский институт кардиологии, Томский национальный исследовательский медицинский центр Российской академии наук; Сибирский государственный медицинский университет Министерства здравоохранения Российской ФедерацииРоссияCardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences; Siberian State Medical UniversityRussian Federation2022191020223734955Copyright © Пантелеев О.О., Рябов В.В., 20222022Пантелеев О.О., Рябов В.В.Panteleev O.O., Ryabov V.V.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.sibjcem.ru/jour/article/view/1502

Делирий является предиктором неблагоприятного исхода как при инфаркте миокарда (ИМ), так и при других нозологиях. Несмотря на рост интереса к данной проблеме, эффективных способов прогнозирования, профилактики и лечения делирия не найдено. Данный обзор литературы освещает актуальные представления об этиологии, патогенезе делирия, подходах к профилактике и лечению, особенностях делирия у больных ИМ, содержит анализ проведенных клинических исследований и метаанализов с выявлением причин их неудач и поиском перспективных направлений для дальнейших исследований этого синдрома.

Delirium is a predictor of poor outcome in both myocardial infarction and other nosologies. Despite the growing interest in this problem, no effective methods for prediction, prevention, and treatment of delirium have been found. This literature review highlights the current ideas about delirium etiology, pathogenesis, approaches to prevention and treatment, and features of delirium in patients with myocardial infarction. The review presents the analysis of clinical trials and meta-analyses with the identification of causes for clinical trials failures and the search for future promising directions of research focusing on this syndrome.

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The authors declare that there are no conflicts of interest present.