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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cardiotomsk</journal-id><journal-title-group><journal-title xml:lang="ru">Сибирский журнал клинической и экспериментальной медицины</journal-title><trans-title-group xml:lang="en"><trans-title>Siberian Journal of Clinical and Experimental Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2713-2927</issn><issn pub-type="epub">2713-265X</issn><publisher><publisher-name>TSU publishing</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.29001/2073-8552-2022-37-4-70-76</article-id><article-id custom-type="elpub" pub-id-type="custom">cardiotomsk-1622</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL STUDIES</subject></subj-group></article-categories><title-group><article-title>Ремоделирование правых отделов сердца и гепатолиенальное кровообращение у больных, перенесших коронавирусную инфекцию</article-title><trans-title-group xml:lang="en"><trans-title>Remodeling of the right heart and hepatolienal circulation in patients with coronavirus infection</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6280-0757</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чистякова</surname><given-names>М. B.</given-names></name><name name-style="western" xml:lang="en"><surname>Chistyakova</surname><given-names>M. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Чистякова Марина Владимировна, доктор медицинских наук, профессор кафедры функциональной и ультразвуковой диагностики</p><p>672000, Чита, ул. Горького, 39а</p></bio><bio xml:lang="en"><p>Marina V. Chistyakova, Dr. Sci. (Med.), Professor, Department of Functional and Ultrasound Diagnostics</p><p>39а, Gorky str., Chita, 672090</p></bio><email xlink:type="simple">m.44444@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1340-9190</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Говорин</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Govorin</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Говорин Анатолий Васильевич, доктор медицинских наук, профессор, заслуженный врач РФ, заслуженный ректор</p><p>672000, Чита, ул. Горького, 39а</p></bio><bio xml:lang="en"><p>Anatoly V. Govorin, Dr. Sci. (Med.), Professor, Honored Doctor of the Russian Federation, Honored Rector</p><p>39а, Gorky str., Chita, 672090</p></bio><email xlink:type="simple">govorav@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7927-7368</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Калинкина</surname><given-names>Т. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kalinkina</surname><given-names>T. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Калинкина Татьяна Владимировна, кандидат медицинских наук, доцент кафедры пропедевтики внутренних болезней</p><p>672000, Чита, ул. Горького, 39а</p><p> </p></bio><bio xml:lang="en"><p>Tatiana V. Kalinkina, Cand. Sci. (Med.), Associate Professor, Department of Propaedeutics of Internal Diseases</p><p>39а, Gorky str., Chita, 672090</p></bio><email xlink:type="simple">kalink-tatyana@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3602-4034</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Медведева</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Medvedeva</surname><given-names>N. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Медведева Наталья Александровна, аспирант кафедры функциональной и ультразвуковой диагностики</p><p>672000, Чита, ул. Горького, 39а</p></bio><bio xml:lang="en"><p>Natalia A. Medvedeva, Postgraduate Student, Department of Functional and Ultrasound Diagnostics</p><p>39а, Gorky str., Chita, 672090</p></bio><email xlink:type="simple">medv-95@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9082-1114</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кудрявцева</surname><given-names>Я. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kudryavtseva</surname><given-names>Ya. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кудрявцева Яна Витальевна, аспирант кафедры функциональной и ультразвуковой диагностики</p><p>672000, Чита, ул. Горького, 39а</p></bio><bio xml:lang="en"><p>Yana V. Kudryavtseva, Postgraduate Student, Department of Functional and Ultrasound Diagnostics</p><p>39а, Gorky str., Chita, 672090</p><p> </p></bio><email xlink:type="simple">jo.water.103@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Читинская государственная медицинская академия Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Chita State Medical Academy</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>17</day><month>01</month><year>2023</year></pub-date><volume>37</volume><issue>4</issue><fpage>70</fpage><lpage>76</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Чистякова М.B., Говорин А.В., Калинкина Т.В., Медведева Н.А., Кудрявцева Я.В., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Чистякова М.B., Говорин А.В., Калинкина Т.В., Медведева Н.А., Кудрявцева Я.В.</copyright-holder><copyright-holder xml:lang="en">Chistyakova M.V., Govorin A.V., Kalinkina T.V., Medvedeva N.A., Kudryavtseva Y.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.sibjcem.ru/jour/article/view/1622">https://www.sibjcem.ru/jour/article/view/1622</self-uri><abstract><sec><title>Цель</title><p>Цель: изучить состояние правых отделов сердца и гепатолиенального кровообращения у пациентов через 3 мес. после COVID-19.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. 87 больным (средний возраст – 36,2 года), пролеченным по поводу COVID-19, через 3 мес. провели эхокардиографию (ЭхоКГ), изучили гепатолиенальный кровоток. Пациентов разделили на группы: 1-я – с КТ 0; 2-я – с двухсторонней пневмонией КТ 1–2, 3-я – с КТ 3–4. Контрольная группа – 22 пациента, не переносивших COVID-19.</p></sec><sec><title>Результаты</title><p>Результаты. У пациентов в 1-й группе увеличивалась диастолическая скорость транстрикуспидального потока на 24% по сравнению с контрольной группой, р &lt; 0,001. Во всех группах снижалось отношение диастолических скоростей Е/А и Еm/Am, наибольшие нарушения установлены в 3-й группе. В 3-й группе повышалось систолическое давление в легочной артерии, увеличивался правый желудочек, фиброзное кольцо и правая ветвь легочной артерии, диаметр нижней полой, воротной и селезеночной вен. Отмечалось снижение скорости потока в селезеночной вене (14%), увеличивался размер печени и селезенки. Установлены корреляционные взаимосвязи между повышенным давлением в легочной артерии и функциональными показателями сердца, гепатолиенального кровотока; между морфофункциональными параметрами сердца и показателями воротной вены, р &lt; 0,001.</p></sec><sec><title>Заключение</title><p>Заключение. Через 3 мес. после COVID-19 у пациентов с легким и умеренным течением заболевания формировалось скрытое нарушение диастолической функции правого желудочка. У больных с тяжелым течением вирусной пневмонии также отмечалось повышение давления в легочной артерии, формировалась дилатация правого желудочка, правой ветви легочной артерии, селезеночной и воротной вен со снижением скорости потока в селезеночной вене, а также увеличивались печень и селезенка.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Aim</title><p>Aim. To study the condition of the right heart and hepatolienal circulation in patients three months after COVID-19.</p></sec><sec><title>Material and Methods</title><p>Material and Methods. A total of 87 patients aged on average 36.2 years who were treated for COVID-19 three months before underwent echocardiography and the study of hepatolienal blood flow. Patients were divided into groups: group 1 comprised patients with CT 0; group 2 comprised patients with bilateral pneumonia CT 1–2, and group 3 comprised patients with CT 3–4. Control group comprised 22 patients who did not undergo COVID–19.</p></sec><sec><title>Results</title><p>Results. In patients of group 1, the diastolic velocity of the transtricuspid flow increased by 24% compared to the control p &lt;0.001. The ratio of diastolic velocities E/A and Em/Am decreased in all groups, and the greatest abnormalities were found in group 3. In group 3, systolic pressure in the pulmonary artery increased; the right ventricle, fibrous ring, right branch of the pulmonary artery, and diameters of the inferior vena cava, portal vein, and splenic veins increased. There was a decrease in the flow rate in the splenic vein (14%), and sizes of the liver and spleen increased. Correlations were established between increased pressure in the pulmonary artery and functional parameters of the heart and hepatolienal blood flow as well as between morpho-functional parameters of the heart and indicators of the portal vein, p &lt; 0.001.</p></sec><sec><title>Conclusion</title><p>Conclusion. Three months after the coronavirus infection, patients with mild and moderate severity of the disease developed subclinical abnormalities in the diastolic function of the right ventricle. In patients with severe viral pneumonia, there was also increased pressure in pulmonary artery; the dilatations of the right ventricle, pulmonary artery, splenic vein, and portal veins developed along with a decrease in the flow rate in the splenic vein and increases in the liver and spleen.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>легочная гипертензия</kwd><kwd>правые отделы сердца</kwd><kwd>гепатолиенальное кровообращение</kwd><kwd>коронавирусная инфекция</kwd></kwd-group><kwd-group xml:lang="en"><kwd>pulmonary hypertension</kwd><kwd>right heart</kwd><kwd>hepatolienal circulation</kwd><kwd>coronavirus infection</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Capotosto L., Nguyen B.L., Ciardi M.R., Mastroianni C., Vitarelli A. Heart, COVID-19, and echocardiography. Echocardiography. 2020;37(9):1454– 1464. 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