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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cardiotomsk</journal-id><journal-title-group><journal-title xml:lang="ru">Сибирский журнал клинической и экспериментальной медицины</journal-title><trans-title-group xml:lang="en"><trans-title>Siberian Journal of Clinical and Experimental Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2713-2927</issn><issn pub-type="epub">2713-265X</issn><publisher><publisher-name>TSU publishing</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.29001/2073-8552-2023-38-2-281-285</article-id><article-id custom-type="elpub" pub-id-type="custom">cardiotomsk-1818</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ СЛУЧАИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL CASES</subject></subj-group></article-categories><title-group><article-title>Хирургическое лечение редкого сочетания ревматического порока митрального клапана и миксомы левого предсердия: клинический случай</article-title><trans-title-group xml:lang="en"><trans-title>Surgical treatment in a rare coexistence of rheumatic mitral stenosis and left atrial myxoma: a case report</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5537-0864</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Евтушенко</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Evtushenko</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Евтушенко Владимир Валериевич - д-р мед. наук, врач, сердечно-сосудистый хирург, кардиохирургическое отделение № 1</p><p>634012, Российская Федерация, Томск, ул. Киевская, 111а </p></bio><bio xml:lang="en"><p>Vladimir V. Evtushenko, Dr. Sci. (Med.), Cardiovascular Surgeon, Department of Cardiac Surgery</p><p> 111 a, Kievskaya str., Tomsk, 634012, Russian Federation </p></bio><email xlink:type="simple">evtushenko.vladimir@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5147-8600</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жилина</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhilina</surname><given-names>A. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Жилина Александра Николаевна - клинический ординатор, кардиохирургическое отделение № 1</p><p>634012, Российская Федерация, Томск, ул. Киевская, 111а </p></bio><bio xml:lang="en"><p>Aleksandra N. Zhilina - Medical Resident, Department of Cardiac Surgery </p><p> 111 a, Kievskaya str., Tomsk, 634012, Russian Federation </p></bio><email xlink:type="simple">alexandra.jilina@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5033-8307</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Черных</surname><given-names>Ю. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Chernykh</surname><given-names>Yu. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Черных Юлия Николаевна, врач-кардиолог,  кардиохирургическое отделение № 1</p><p>634012, Российская Федерация, Томск, ул. Киевская, 111а </p></bio><bio xml:lang="en"><p> Yulia N. Chernykh - Cardiologist, Department of Cardiac Surgery </p><p> 111 a, Kievskaya str., Tomsk, 634012, Russian Federation </p></bio><email xlink:type="simple">juliasap@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1574-7388</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Катков</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Katkov</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Катков Вадим Анатольевич, врач функциональной диагностики отделения функциональной и ультразвуковой диагностики</p><p>634012, Российская Федерация, Томск, ул. Киевская, 111а </p></bio><bio xml:lang="en"><p>Vadim A. Katkov - Sonologist, Department of Functional and Ultrasound Diagnostics</p><p> 111 a, Kievskaya str., Tomsk, 634012, Russian Federation </p></bio><email xlink:type="simple">blanket1984@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Научно-исследовательский институт кардиологии, Томский национальный исследовательский медицинский центр Российской академии наук</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Cardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>10</day><month>07</month><year>2023</year></pub-date><volume>38</volume><issue>2</issue><fpage>281</fpage><lpage>285</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Евтушенко В.В., Жилина А.Н., Черных Ю.Н., Катков В.А., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Евтушенко В.В., Жилина А.Н., Черных Ю.Н., Катков В.А.</copyright-holder><copyright-holder xml:lang="en">Evtushenko V.V., Zhilina A.N., Chernykh Y.N., Katkov V.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.sibjcem.ru/jour/article/view/1818">https://www.sibjcem.ru/jour/article/view/1818</self-uri><abstract><p>Наиболее характерным кардиальным доброкачественным новообразованием является миксома сердца с наиболее типичной ее локализацией в левом предсердии (ЛП). Это патология с неспецифической клинической картиной, требующая применения инструментальных методов исследования для верификации диагноза. В данной статье описан клинический случай редкого сочетания миксомы сердца, проявляющейся симптомами динамической обструкции митрального клапана (МК), с ревматической болезнью сердца и хронической обструктивной болезнью легких (ХОБЛ). Трудности в первичной постановке диагноза новообразования сердца были обусловлены схожестью клинической симптоматики вышеуказанных заболеваний.</p></abstract><trans-abstract xml:lang="en"><p> The most frequent benign cardiac tumor is a cardiac myxoma with its favorite location in left atrium. The disease has no specific symptoms and requires paraclinical diagnostic methods. We report a rare case of the left atrial myxoma with dynamic mitral valve obstruction symptoms associated with rheumatic mitral stenosis and chronic obstructive pulmonary disease. There are difficulties with interpretation of the case due to similarity of clinical presentation the  diseases. </p></trans-abstract><kwd-group xml:lang="ru"><kwd>миксома сердца</kwd><kwd>миксома левого предсердия</kwd><kwd>новообразования в сердце</kwd><kwd>ревматическая болезнь сердца</kwd><kwd>хирургическое лечение миксомы</kwd><kwd>динамическая обструкция митрального клапана</kwd><kwd>клинический случай</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Left atrial myxoma</kwd><kwd>cardiac tumor</kwd><kwd>rheumatic heart disease</kwd><kwd>rheumatic mitral stenosis</kwd><kwd>surgical treatment of atrial myxoma</kwd><kwd>dynamic mitral valve obstruction</kwd><kwd>clinical case</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Финансирование работы выполнено в рамках клинической и научной деятельности Научно-исследовательского института кардиологии Томского НИМЦ</funding-statement><funding-statement xml:lang="en">The work was conducted at the cost of federal budget of Federal State Budgetary Scientific Institution «Tomsk National Research Medical Center of the Russian Academy of Sciences».</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Butany J., Nair V., Naseemuddin A., Nair G.M., Catton C., Yau T. Cardiac tumours: diagnosis and management. Lancet Oncol. 2005;6(4):219–228. DOI: 10.1016/S1470-2045(05)70093-0.</mixed-citation><mixed-citation xml:lang="en">Butany J., Nair V., Naseemuddin A., Nair G.M., Catton C., Yau T. Cardiac tumours: diagnosis and management. Lancet Oncol. 2005;6(4):219–228. DOI: 10.1016/S1470-2045(05)70093-0.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Elbardissi A.W., Dearani J.A., Daly R.C., Mullany C.J., Orszulak T.A., Puga F.J. et al. Survival after resection of primary cardiac tumors: a 48-year experience. Circulation. 2008;118(14):7–15. DOI:10.1161/CIRCULATIONAHA.107.783126.</mixed-citation><mixed-citation xml:lang="en">Elbardissi A.W., Dearani J.A., Daly R.C., Mullany C.J., Orszulak T.A., Puga F.J. et al. Survival after resection of primary cardiac tumors: a 48-year experience. Circulation. 2008;118(14):7–15. DOI:10.1161/CIRCULATIONAHA.107.783126.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Wang J.G., Li Y.J., Liu H., Li N.N., Zhao J., Xing X.M. Clinicopathologic analysis of cardiac myxomas: Seven years ҆ experience with 61 patients. J. Thorac. Dis. 2012;4(3):272–283. DOI: 10.3978/j.issn.2072-1439.2012.05.07.</mixed-citation><mixed-citation xml:lang="en">Wang J.G., Li Y.J., Liu H., Li N.N., Zhao J., Xing X.M. Clinicopathologic analysis of cardiac myxomas: Seven years ҆ experience with 61 patients. J. Thorac. Dis. 2012;4(3):272–283. DOI: 10.3978/j.issn.2072-1439.2012.05.07.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Garatti A., Nano G., Canziani A., Gagliardotto P., Mossuto E., Frigiola A. et al. Surgical excision of cardiac myxomas: twenty years experience at a single institution. Ann. Thorac. Surg. 2012;93(3):825–831. DOI: 10.1016/j.athoracsur.2011.11.009.</mixed-citation><mixed-citation xml:lang="en">Garatti A., Nano G., Canziani A., Gagliardotto P., Mossuto E., Frigiola A. et al. Surgical excision of cardiac myxomas: twenty years experience at a single institution. Ann. Thorac. Surg. 2012;93(3):825–831. DOI: 10.1016/j.athoracsur.2011.11.009.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Shah I.K., Dearani J.A., Daly R.C., Suri R.M., Park S.J., Joyce L.D. et al. Cardiac Myxomas: A 50-year experience with resection and analysis of risk factors for recurrence. Ann. Thorac. Surg. 2015;100(2):495–500. DOI: 10.1016/j.athoracsur.2015.03.007.</mixed-citation><mixed-citation xml:lang="en">Shah I.K., Dearani J.A., Daly R.C., Suri R.M., Park S.J., Joyce L.D. et al. Cardiac Myxomas: A 50-year experience with resection and analysis of risk factors for recurrence. Ann. Thorac. Surg. 2015;100(2):495–500. DOI: 10.1016/j.athoracsur.2015.03.007.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Thyagarajan B., Kumar M.P., Patel S., Agrawal A. Extracardiac manifestations of atrial myxomas. J. Saudi Heart Assoc. 2017;29(1):37–43. DOI: 10.1016/j.jsha.2016.07.003.</mixed-citation><mixed-citation xml:lang="en">Thyagarajan B., Kumar M.P., Patel S., Agrawal A. Extracardiac manifestations of atrial myxomas. J. Saudi Heart Assoc. 2017;29(1):37–43. DOI: 10.1016/j.jsha.2016.07.003.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Cho J., Quach S., Reed J., Osian O. Case report: left atrial Myxoma causing elevated C-reactive protein, fatigue and fever, with literature review. BMC Cardiovasc. Disord. 2020;20(119). DOI: 10.1186/s12872-020-01397-1.</mixed-citation><mixed-citation xml:lang="en">Cho J., Quach S., Reed J., Osian O. Case report: left atrial Myxoma causing elevated C-reactive protein, fatigue and fever, with literature review. BMC Cardiovasc. Disord. 2020;20(119). DOI: 10.1186/s12872-020-01397-1.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Цой Е.И., Фальковская А.Ю., Евтушенко В.В., Мордовин В.Ф. Случай быстропрогрессирующей миксомы сердца со злокачественным клиническим течением после инфекции COVID-19. Кардиология. 2022;62(9):74–78. DOI: 10.18087/cardio.2022.9.n1624.</mixed-citation><mixed-citation xml:lang="en">Tsoi E.I., Falkovskaya A.Yu., Evtushenko V.V., Mordovin V.F. A case of clinically malignant rapid-progressive cardiac myxoma after COVID-19 infection. Kardiologiia. 2022;62(9):74–78. (In Russ.). DOI: 10.18087/cardio.2022.9.n1624.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Mendoza C.E., Rosado M.F., Bernal L. The role of interleukin-6 in cases of cardiac myxoma. Clinical features, immunologic abnormalities, and a possible role in recurrence. Tex. Heart Inst. J. 2001;28(1):3–7. URL: https://pubmed.ncbi.nlm.nih.gov/11330738/ (12.01.2023).</mixed-citation><mixed-citation xml:lang="en">Mendoza C.E., Rosado M.F., Bernal L. The role of interleukin-6 in cases of cardiac myxoma. Clinical features, immunologic abnormalities, and a possible role in recurrence. Tex. Heart Inst. J. 2001;28(1):3–7. URL: https://pubmed.ncbi.nlm.nih.gov/11330738/ (12.01.2023).</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Seagle R.L., Nomeir A.M., Watts L.E. Left atrial myxoma associated with rheumatic mitral stenosis. Clin. Cardiol. 1984;7(6):370–372. DOI: 10.1002/clc.4960070609.</mixed-citation><mixed-citation xml:lang="en">Seagle R.L., Nomeir A.M., Watts L.E. Left atrial myxoma associated with rheumatic mitral stenosis. Clin. Cardiol. 1984;7(6):370–372. DOI: 10.1002/clc.4960070609.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Moustafa S., Bégin L.R., Souliere V. Image. Inadvertent coexistence of atrial myxoma and mitral stenosis. Arch. Cardiovasc. Dis. 2009;102(6–7):583–584. DOI: 10.1016/j.acvd.2009.02.010.</mixed-citation><mixed-citation xml:lang="en">Moustafa S., Bégin L.R., Souliere V. Image. Inadvertent coexistence of atrial myxoma and mitral stenosis. Arch. Cardiovasc. Dis. 2009;102(6–7):583–584. DOI: 10.1016/j.acvd.2009.02.010.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
