cardiotomskСибирский журнал клинической и экспериментальной медициныSiberian Journal of Clinical and Experimental Medicine2713-29272713-265XTSU publishing10.29001/2073-8552-2022-564cardiotomsk-1871Research ArticleОБЗОРЫ И ЛЕКЦИИREVIEWS AND LECTURESИсторические и современные аспекты хирургического лечения гипертрофической кардиомиопатии у детей (обзор литературы)Historical and modern aspects of surgical treatment of hypertrophic cardiomyopathy in children (literature review)https://orcid.org/0000-0002-0493-4762КожановР. С.KozhanovR. S.

Кожанов Роман Сергеевич, аспирант, сердечно-сосудистый хирург, кардиохирургическое отделение № 2

634012, Томск, ул. Киевская, 111а

Roman S. Kozhanov, Graduate Student, Cardiovascular Surgeon, Department of Cardiac Surgery No. 2

111a, Kievskaya str., Tomsk, 634012

romankozhanoff@yandex.ruhttps://orcid.org/0000-0003-4023-455XЕгуновО. А.EgunovO. A.

Егунов Олег Анатольевич, сердечно-сосудистый хирург, кардиохирургическое отделение № 2

634012, Томск, ул. Киевская, 111а

Оleg A. Egunov, Cardiovascular Surgeon, Department of Cardiac Surgery No. 2

111a, Kievskaya str., Tomsk, 634012

egunov_oleg@mail.ruhttps://orcid.org/0000-0002-6907-381XСвязовЕ. А.SvyazovE. A.

Связов Евгений Александрович, канд. мед. наук, сердечно-сосудистый хирург, кардиохирургическое отделение № 2

634012, Томск, ул. Киевская, 111а

Evgeny A. Svyazov, Cand. Sci. (Med.), Cardiovascular Surgeon, Department of Cardiac Surgery No. 2

111a, Kievskaya str., Tomsk, 634012

svyazoff@gmail.comhttps://orcid.org/0000-0002-0828-3995КривощековЕ. В.KrivoshchekovE. V.

Кривощеков Евгений Владимирович, д-р мед. наук, сердечно-сосудистый хирург, заведующий отделением, кардиохирургическое отделение № 2

634012, Томск, ул. Киевская, 111а

Evgeny V. Krivoshchekov, Dr. Sci. (Med.), Cardiovascular Surgeon, Head of the Department of Cardiac Surgery No. 2

111a, Kievskaya str., Tomsk, 634012

kev@cardio-tomsk.ruНаучно-исследовательский институт кардиологии, Томский национальный исследовательский медицинский центр Российской академии наукРоссияCardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of SciencesRussian Federation2023301220233847785Copyright © Кожанов Р.С., Егунов О.А., Связов Е.А., Кривощеков Е.В., 20232023Кожанов Р.С., Егунов О.А., Связов Е.А., Кривощеков Е.В.Kozhanov R.S., Egunov O.A., Svyazov E.A., Krivoshchekov E.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.sibjcem.ru/jour/article/view/1871

Гипертрофическая кардиомиопатия (ГКМП) – частая генетически детерминированная патология миокарда, которая может проявляться в любом возрасте. Манифестация данной патологии в детском возрасте всегда означает высокий риск внезапной сердечной смерти и быстрое прогрессирование симптомов. Ежегодная смертность у бессимптомных пациентов старше 1 года составляет 1%. Существует множество рекомендаций по ведению пациентов с обструктивной кардиомиопатией, однако все они составлены для взрослой популяции. Медикаментозное лечение симптоматических пациентов с данной патологией эффективно лишь у 70% пациентов. У остальных 30% следует отдавать предпочтение хирургическому лечению. Для кардиохирурга важно знать основные методы коррекции ГКМП, их преимущества и недостатки. В литературном обзоре показана эволюция методов хирургической коррекции обструктивной ГКМП с середины XX в. по настоящее время. Представлены основные хирургические способы устранения динамического градиента на выводном отделе левого желудочка (ВОЛЖ), коррекции SAM-синдрома (systolic anterior motion syndrome) и митральной недостаточности, оказавших большое влияние на развитие хирургии ГКМП. Приведен клинический опыт устранения обструкции на ВОЛЖ у детей. Наиболее многообещающим на сегодняшний день является метод трансаортальной расширенной септальной миоэктомии. Таким образом, существует необходимость оценки и модификации уже имеющихся способов коррекции обструктивной ГКМП и их осложнений. Работы, направленные на их усовершенствование и устранение недостатков, являются перспективными.

Hypertrophic cardiomyopathy (HCM) is a common, genetically determined myocardial pathology that can manifest itself at any age. The manifestation of this pathology in childhood always means a high risk of sudden cardiac death and the rapid progression of symptoms. The annual mortality in asymptomatic patients over 1 year is 1%. There are many recommendations for the management of patients with obstructive cardiomyopathy, but they are all written for the adult population. Drug treatment of symptomatic patients with this pathology is effective only in 70% of patients. The remaining 30% should be given preference to surgical treatment. It is important for a cardiac surgeon to know the main methods of HCM correction, their advantages and disadvantages. The literature review shows the evolution of methods of surgical correction of obstructive HCM from the middle of the 20th century until now. The main surgical methods for treating left ventricular outflow tract obstruction, correcting SAM-syndrome (systolic anterior motion syndrome) and mitral insufficiency, which have had a great influence on the development of HCM surgery, are presented. A clinical experience of treating left ventricular outflow tract obstruction in children is presented. The most promising method today is “transaortic extended septal myectomy”. Thus, there is a need to evaluate and modify existing methods for correcting obstructive HCM and their complications. Works aimed at their improvement and elimination of shortcomings are promising.

обструктивная гипертрофическая кардиомиопатиярасширенная трансаортальная миоэктомияобструкция выводного отдела левого желудочкаobstructive hypertrophic cardiomyopathyextended septal myectomyobstruction of the outflow tract of the left ventricleReferencesДземешкевич С.Л., Мотрева А.П., Калачанова Е.П., Никитюк Т.Г., Мартьянова Ю.Б., Калмыкова О.В. и др. Манифестация гипертрофической кардиомиопатии у детей: фенотип, генотип и особенности хирургического лечения. Клиническая и экспериментальная хирургия. Журнал имени Б.В. Петровского. 2021;3(9):16–24. DOI: 10.33029/2308-1198-2021-9-3-16-24.Dzemeshkevich S.L., Motreva A.P., Kalachanova E.P., Nikityuk T.G., Martyanova Yu.B., Kalmykova O.V. et al. Manifestation of hypertrophic cardiomyopathy in children: phenotype, genotype and features of surgical treatment. Clinical and Experimental Surgery. Petrovsky Journal. 2021;9(3):16–24. (In Russ.). DOI: 10.33029/2308-1198-2021-9-3-16-24.Semsarian C., Ingles J., Maron M.S., Maron B.J. New perspectives on the prevalence of hypertrophic cardiomyopathy. J. Am. Coll. Cardiol. 2015;65(12):1249–1254. DOI: 10.1016/j.jacc.2015.01.019.Semsarian C., Ingles J., Maron M.S., Maron B.J. New perspectives on the prevalence of hypertrophic cardiomyopathy. J. Am. Coll. Cardiol. 2015;65(12):1249–1254. DOI: 10.1016/j.jacc.2015.01.019.Maron B.J., Gardin J.M., Flack J.M., Gidding S.S., Kurosaki T.T., Bild D.E. Prevalence of hypertrophic cardiomyopathy in a general population of young adults. Echocardiographic analysis of 4111 subjects in the CARDIA Study. Coronary artery risk development in (young) adults. Circulation. 1995;92:785– 789. DOI: 10.1161/01.cir.92.4.785.Maron B.J., Gardin J.M., Flack J.M., Gidding S.S., Kurosaki T.T., Bild D.E. Prevalence of hypertrophic cardiomyopathy in a general population of young adults. Echocardiographic analysis of 4111 subjects in the CARDIA Study. Coronary artery risk development in (young) adults. Circulation. 1995;92:785– 789. DOI: 10.1161/01.cir.92.4.785.Teare D. Asymmetrical hypertrophy of the heart in young adults. Br. Heart J. 1958; 20(1):1–8. DOI: 10.1136/hrt.20.1.1.Teare D. Asymmetrical hypertrophy of the heart in young adults. Br. Heart J. 1958; 20(1):1–8. DOI: 10.1136/hrt.20.1.1.Maron M.S., Olivitto I., Betocchi S., Casey S.A., Lesser J.R., Maria A.L. et al. Effect of left ventricular outflow tract obstruction on clinical outcome in hypertrophic cardiomyopathy. N. Engl. J. Med. 2003;348(4):295–303. DOI: 10.1056/NEJMoa021332.Maron M.S., Olivitto I., Betocchi S., Casey S.A., Lesser J.R., Maria A.L. et al. Effect of left ventricular outflow tract obstruction on clinical outcome in hypertrophic cardiomyopathy. N. Engl. J. Med. 2003;348(4):295–303. DOI: 10.1056/NEJMoa021332.Brock R. Functional obstruction of the left ventricle; acquired aortic subvalvar stenosis. Guy's Hospital reports. 1957;106(4):221–238.Brock R. Functional obstruction of the left ventricle; acquired aortic subvalvar stenosis. Guy's Hospital reports. 1957;106(4):221–238.Cleland W.P. The surgical management of obstructive cardiomyopathy. J. Cardiovasc. Surg. (Torino). 1963;4:489–491.Cleland W.P. The surgical management of obstructive cardiomyopathy. J. Cardiovasc. Surg. (Torino). 1963;4:489–491.Iwata Y., Imai Y., Shin’oka T., Kurosawa H. Subaortic stenosis associated with systolic anterior motion. Heart and vessels. 2008;23(6):436–439. DOI: 10.1007/s00380-008-1078-1.Iwata Y., Imai Y., Shin’oka T., Kurosawa H. Subaortic stenosis associated with systolic anterior motion. Heart and vessels. 2008;23(6):436–439. DOI: 10.1007/s00380-008-1078-1.Menon S.C., Eidem B.W., Dearani J.A., Ommen S.R., Ackerman M.J., Miller D. Diastolic dysfunction and its histopathological correlation in obstructive hypertrophic cardiomyopathy in children and adolescents. J. Am. Soc. Echocardiogr. 2009;22(12):1327–1334. DOI: 10.1016/j.echo.2009.08.014.Menon S.C., Eidem B.W., Dearani J.A., Ommen S.R., Ackerman M.J., Miller D. Diastolic dysfunction and its histopathological correlation in obstructive hypertrophic cardiomyopathy in children and adolescents. J. Am. Soc. Echocardiogr. 2009;22(12):1327–1334. DOI: 10.1016/j.echo.2009.08.014.Maron M.S., Olivotto I., Zenovich A.G., Link M.S., Pandian N.G., Kuvin J.T. et al. Hypertrophic cardiomyopathy is predominantly a disease of left ventricular outflow tract obstruction. Circulation. 2006;114(21):2232–2239. DOI: 10.1161/CIRCULATIONAHA.106.644682.Maron M.S., Olivotto I., Zenovich A.G., Link M.S., Pandian N.G., Kuvin J.T. et al. Hypertrophic cardiomyopathy is predominantly a disease of left ventricular outflow tract obstruction. Circulation. 2006;114(21):2232–2239. DOI: 10.1161/CIRCULATIONAHA.106.644682.Gersh B.J., Maron B.J., Bonow R.O., Dearani J.A., Fifer M.A., Mark S. et al. 2011 ACCF/AHA guideline for the diagnosis and treatment of hypertrophic cardiomyopathy: executive summary: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation. 2011;124(24):2761–2796. DOI: 10.1161/CIR.0b013e318223e230.Gersh B.J., Maron B.J., Bonow R.O., Dearani J.A., Fifer M.A., Mark S. et al. 2011 ACCF/AHA guideline for the diagnosis and treatment of hypertrophic cardiomyopathy: executive summary: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation. 2011;124(24):2761–2796. DOI: 10.1161/CIR.0b013e318223e230.Xu H., Yan J., Wang Q., Li D., Guo H., Li S. et al. Extended septal myectomy for hypertrophic obstructive cardiomyopathy in children and adolescents. Pediatric Cardiology. 2016;37(6):1091–1097. DOI: 10.1007/s00246-016-1396-5.Xu H., Yan J., Wang Q., Li D., Guo H., Li S. et al. Extended septal myectomy for hypertrophic obstructive cardiomyopathy in children and adolescents. Pediatric Cardiology. 2016;37(6):1091–1097. DOI: 10.1007/s00246-016-1396-5.Maron B.J., Desai M.Y., Nishimura R.A., Spirito P., Rakowski H., Towbin J.A. et al. Management of hypertrophic cardiomyopathy JACC State-of-the-Art Review. J. Am. Coll. Cardiol. 2022;79(4):390–414. DOI: 10.1016/j.jacc.2021.11.021.Maron B.J., Desai M.Y., Nishimura R.A., Spirito P., Rakowski H., Towbin J.A. et al. Management of hypertrophic cardiomyopathy JACC State-of-the-Art Review. J. Am. Coll. Cardiol. 2022;79(4):390–414. DOI: 10.1016/j.jacc.2021.11.021.Габрусенко С.А., Гудкова А.Я., Козиолова Н.А., Александрова С.А., Берсенева М.И., Гордеева М.Л. и др. Гипертрофическая кардиомиопатия. Клинические рекомендации 2020. Российский кардиологический журнал. 2021;26(5):269–333. DOI: 10.15829/1560-4071-2021-4541.Gabrusenko S.A., Gudkova A.Ya., Koziolova N.A., Alexandrova S.A., Berseneva M.I., Gordeev M.L. et al. 2020 Clinical practice guidelines for Hypertrophic cardiomyopathy. Russian Journal of Cardiology. 2021;26(5):269–333. (In Russ.). DOI: 10.15829/1560-4071-2021-4541.Hang D., Nguyen A., Schaff H.V. Surgical treatment for hypertrophic cardiomyopathy: a historical perspective. Ann. Cardiothorac. Surg. 2017;6(4):318–328. DOI: 10.21037/acs.2017.04.03.Hang D., Nguyen A., Schaff H.V. Surgical treatment for hypertrophic cardiomyopathy: a historical perspective. Ann. Cardiothorac. Surg. 2017;6(4):318–328. DOI: 10.21037/acs.2017.04.03.Wang S., Luo M., Sun H., Song Y., Yin C., Wang L. et al. A retrospective clinical study of transaortic extended septal myectomy for obstructive hypertrophic cardiomyopathy in China. Eur. J. Cardiothoracic Surg. 2013;43(3):534–540. DOI: 10.1093/ejcts/ezs332.Wang S., Luo M., Sun H., Song Y., Yin C., Wang L. et al. A retrospective clinical study of transaortic extended septal myectomy for obstructive hypertrophic cardiomyopathy in China. Eur. J. Cardiothoracic Surg. 2013;43(3):534–540. DOI: 10.1093/ejcts/ezs332.Arghami A., Dearani J.A., Said S.M., O’Leary P.W., Schaff H.V. Hypertrophic cardiomyopathy in children. Ann. Cardiothorac. Surg. 2017;6(4):376–385. DOI: 10.21037/acs.2017.07.04.Arghami A., Dearani J.A., Said S.M., O’Leary P.W., Schaff H.V. Hypertrophic cardiomyopathy in children. Ann. Cardiothorac. Surg. 2017;6(4):376–385. DOI: 10.21037/acs.2017.07.04.Леонтьева И.В., Макарова В.А. Гипертрофическая кардиомиопатия у детей. Российский вестник перинатологии в педиатрии. 2013;5:23–33.Leontyeva I.V., Makarova V.A. Hypertrophic cardiomyopathy in children. Rossiyskiy Vestnik Perinatologii v Pediatr. 2013;5:23–33. (In Russ.).Maron B.J., Maron M.S., Semsarian C. Genetics of hypertrophic cardiomyopathy after 20 years: clinical perspectives. J. Am. Coll. Cardiol. 2012;60(8):705–715. DOI: 10.1016/j.jacc.2012.02.068.Maron B.J., Maron M.S., Semsarian C. Genetics of hypertrophic cardiomyopathy after 20 years: clinical perspectives. J. Am. Coll. Cardiol. 2012;60(8):705–715. DOI: 10.1016/j.jacc.2012.02.068.Marian A.J., Braunwald E. Hypertrophic cardiomyopathy: genetics, pathogenesis, clinical manifestations, diagnosis, and therapy. Circulation research. 2017;121(7):749–770. DOI: 10.1161/CIRCRESAHA.117.311059.Marian A.J., Braunwald E. Hypertrophic cardiomyopathy: genetics, pathogenesis, clinical manifestations, diagnosis, and therapy. Circulation research. 2017;121(7):749–770. DOI: 10.1161/CIRCRESAHA.117.311059.Wu J.J., Seco M., Medi C., Semsarian C., Richmond D.R., Dearani J.A. et al. Surgery for hypertrophic cardiomyopathy. Biophys. Rev. 2015;7(1):117–125. DOI: 10.1007/s12551-014-0153-3.Wu J.J., Seco M., Medi C., Semsarian C., Richmond D.R., Dearani J.A. et al. Surgery for hypertrophic cardiomyopathy. Biophys. Rev. 2015;7(1):117–125. DOI: 10.1007/s12551-014-0153-3.Binder J, Ommen S.R., Gersh B.J., Van Driest S.L., Tajik A.J., Nishimura R.A. et al. Echocardiography-guided genetic testing in hypertrophic cardiomyopathy: septal morphological features predict the presence of myofilament mutations. Mayo Clin. Proc. 2006; 81(4):459–467. DOI: 10.4065/81.4.459.Binder J, Ommen S.R., Gersh B.J., Van Driest S.L., Tajik A.J., Nishimura R.A. et al. Echocardiography-guided genetic testing in hypertrophic cardiomyopathy: septal morphological features predict the presence of myofilament mutations. Mayo Clin. Proc. 2006; 81(4):459–467. DOI: 10.4065/81.4.459.Maron B.J., Ommen S.R., Semsarian C., Spirito P., Olivotto I., Maron M.S. Hypertrophic cardiomyopathy. Present and Future, with translation into contemporary cardiovascular medicine. J. Am. Coll. Cardiol. 2014;64(1):83–99. DOI: 10.1016/j.jacc.2014.05.003.Maron B.J., Ommen S.R., Semsarian C., Spirito P., Olivotto I., Maron M.S. Hypertrophic cardiomyopathy. Present and Future, with translation into contemporary cardiovascular medicine. J. Am. Coll. Cardiol. 2014;64(1):83–99. DOI: 10.1016/j.jacc.2014.05.003.Gersh B.J., Maron B.J., Bonow R.O., Dearani J.A., Fifer M.A., Link M.S. et al. ACCF/AHA guideline for the diagnosis and treatment of hypertrophic cardiomyopathy: Executive summary: A report of the American College of cardiology foundation/ American heart association task force on practice guidelines. Circulation. 2011;124(24):2761–2796. DOI: 10.1161/CIR.0b013e318223e230.Gersh B.J., Maron B.J., Bonow R.O., Dearani J.A., Fifer M.A., Link M.S. et al. ACCF/AHA guideline for the diagnosis and treatment of hypertrophic cardiomyopathy: Executive summary: A report of the American College of cardiology foundation/ American heart association task force on practice guidelines. Circulation. 2011;124(24):2761–2796. DOI: 10.1161/CIR.0b013e318223e230.Harris K.M., Spirito P., Maron M.S., Zenovich A.G., Formisano F., Lesser R.J. et al. Prevalence, clinical profile and significance of left ventricular remodeling in the end-stage phase of hypertrophic cardiomyopathy. Circulation. 2016;114(3):216–225. DOI: 10.1161/CIRCULATIONAHA.105.583500.Harris K.M., Spirito P., Maron M.S., Zenovich A.G., Formisano F., Lesser R.J. et al. Prevalence, clinical profile and significance of left ventricular remodeling in the end-stage phase of hypertrophic cardiomyopathy. Circulation. 2016;114(3):216–225. DOI: 10.1161/CIRCULATIONAHA.105.583500.Altarabsheh S.E., Dearani J.A., Burkhart H.M., Schaff H.V., Deo S.V., Eidem B.W. et al. Outcome of septal myectomy for obstructive hypertrophic cardiomyopathy in children and young adults. Ann. Thorac. Surg. 2013;95(2):663– 669. DOI: 10.1016/j.athoracsur.2012.08.011.Altarabsheh S.E., Dearani J.A., Burkhart H.M., Schaff H.V., Deo S.V., Eidem B.W. et al. Outcome of septal myectomy for obstructive hypertrophic cardiomyopathy in children and young adults. Ann. Thorac. Surg. 2013;95(2):663– 669. DOI: 10.1016/j.athoracsur.2012.08.011.Sun D., Schaff H.V., Nishimura R.A., Geske B.J., Dearani J.A., Ommen S.R. Surgical management of diastolic heart failure after septal myectomy for obstructive hypertrophic cardiomyopathy. JTCVS Tech. 2021;11:21–26. DOI: 10.1016/j.xjtc.2021.10.050.Sun D., Schaff H.V., Nishimura R.A., Geske B.J., Dearani J.A., Ommen S.R. Surgical management of diastolic heart failure after septal myectomy for obstructive hypertrophic cardiomyopathy. JTCVS Tech. 2021;11:21–26. DOI: 10.1016/j.xjtc.2021.10.050.Minakata K., Dearani J.A., O’Leary P.W., Danielson G.K. Septal myectomy for obstructive hypertrophic cardiomyopathy in pediatric patients: early and late results. Ann. Thorac. Surg. 2005;80(4):1424–1430. DOI: 10.1016/j.athoracsur.2005.03.109.Minakata K., Dearani J.A., O’Leary P.W., Danielson G.K. Septal myectomy for obstructive hypertrophic cardiomyopathy in pediatric patients: early and late results. Ann. Thorac. Surg. 2005;80(4):1424–1430. DOI: 10.1016/j.athoracsur.2005.03.109.Goodwin J.F., Hollman A., Cleland W.P., Teare D. Obstructive cardiomyopathy simulating aortic stenosis. Br. Heart J. 1960;22(3):403–414. DOI: 10.1136/hrt.22.3.403.Goodwin J.F., Hollman A., Cleland W.P., Teare D. Obstructive cardiomyopathy simulating aortic stenosis. Br. Heart J. 1960;22(3):403–414. DOI: 10.1136/hrt.22.3.403.Kirklin J.W., Ellis F.H. Surgical relief of diffuse subvalvular aortic stenosis. Circulation. 1961;24:739–742. DOI: 10.1161/01.cir.24.4.739.Kirklin J.W., Ellis F.H. Surgical relief of diffuse subvalvular aortic stenosis. Circulation. 1961;24:739–742. DOI: 10.1161/01.cir.24.4.739.Frye R.L., Kincaid O.W., Swan H.J., Kirklin J.W. Results of surgical treatment of patients with diffuse subvalvular aortic stenosis. Circulation. 1965;32:52–57. DOI: 10.1161/01.cir.32.1.52.Frye R.L., Kincaid O.W., Swan H.J., Kirklin J.W. Results of surgical treatment of patients with diffuse subvalvular aortic stenosis. Circulation. 1965;32:52–57. DOI: 10.1161/01.cir.32.1.52.Morrow A.G., Lambrew C.T., Braunwald E. Idiopathic hypertrophic subaortic stenosis. II. Operative treatment and the results of pre- and postoperative hemodynamic evaluations. Circulation. 1964;30(4):120–151.Morrow A.G., Lambrew C.T., Braunwald E. Idiopathic hypertrophic subaortic stenosis. II. Operative treatment and the results of pre- and postoperative hemodynamic evaluations. Circulation. 1964;30(4):120–151.Lillehei C.W., Levy J. Transatrial exposure for correction of subaortic. JAMA. 1963;186(1):8–13. DOI: 10.1001/jama.1963.03710010042005.Lillehei C.W., Levy J. Transatrial exposure for correction of subaortic. JAMA. 1963;186(1):8–13. DOI: 10.1001/jama.1963.03710010042005.Julian O.C., Dye W.S., Javid H., Hunter J.A., Muenster J.J., Najafi H. Apical left ventriculotomy in subaortic stenosis due to a fibromuscular hypertrophy. Circulation. 1965;31(1):44–56. DOI: 10.1161/01.CIR.31.4S1.I-44.Julian O.C., Dye W.S., Javid H., Hunter J.A., Muenster J.J., Najafi H. Apical left ventriculotomy in subaortic stenosis due to a fibromuscular hypertrophy. Circulation. 1965;31(1):44–56. DOI: 10.1161/01.CIR.31.4S1.I-44.Morrow A.G., Brockenbrough E.C. Surgical treatment of idiopathic hypertrophic subaortic stenosis: technic and hemodynamic results of subaortic ventriculomyotomy. Ann. Surg. 1961;154(2):181–189. DOI: 10.1097/00000658196108000-00003.Morrow A.G., Brockenbrough E.C. Surgical treatment of idiopathic hypertrophic subaortic stenosis: technic and hemodynamic results of subaortic ventriculomyotomy. Ann. Surg. 1961;154(2):181–189. DOI: 10.1097/00000658196108000-00003.Morrow A.G., Fogarty T.J., Hannah H., Braunwald E. Operative treatment in idiopathic hypertrophic subaortic stenosis. Techniques, and the results of preoperative and postoperative clinical and hemodynamic assessments. Circulation. 1968;37(4):589–596. DOI: 10.1161/01.cir.37.4.589.Morrow A.G., Fogarty T.J., Hannah H., Braunwald E. Operative treatment in idiopathic hypertrophic subaortic stenosis. Techniques, and the results of preoperative and postoperative clinical and hemodynamic assessments. Circulation. 1968;37(4):589–596. DOI: 10.1161/01.cir.37.4.589.Morrow A.G. Hypertrophic subaortic stenosis. Operative methods utilized to relieve left ventricular outflow obstruction. J. Thorac. Cardiovasc. Surg. 1978;76(4):423–430.Morrow A.G. Hypertrophic subaortic stenosis. Operative methods utilized to relieve left ventricular outflow obstruction. J. Thorac. Cardiovasc. Surg. 1978;76(4):423–430.Cooley D.A., Bloodwell R.D., Hallman G.L., Lasorte A.F., Leachman R.D., Chapman D.W. Surgical treatment of muscular subaortic stenosis results from septectomy in twenty-six patients. Circulation. 1967;35(4):124–132. DOI: 10.1161/01.CIR.35.4S1.I-124.Cooley D.A., Bloodwell R.D., Hallman G.L., Lasorte A.F., Leachman R.D., Chapman D.W. Surgical treatment of muscular subaortic stenosis results from septectomy in twenty-six patients. Circulation. 1967;35(4):124–132. DOI: 10.1161/01.CIR.35.4S1.I-124.Бокерия Л.А., Борисов К.В., Синёв А.Ф., Злочевская Е.В. Хирургическое лечение гипертрофической обструктивной кардиомиопатии у детей. Детские болезни сердца и сосудов. 2005;1:23–29.Bokerija L.A., Borisov K.V., Sinjov A.F., Zlochevskaja E.V. Hirurgicheskoe lechenie gipertroficheskoj obstruktivnoj kardiomiopatii u detej. Children’s Heart and Vascular Diseases. 2005;1:26–29. (In Russ.).Messmer B.J. Extended myectomy for hypertrophic obstructive cardiomyopathy. Ann. Surg. 1994;58(2):575–577. DOI: 10.1016/0003-4975(94)92268-3.Messmer B.J. Extended myectomy for hypertrophic obstructive cardiomyopathy. Ann. Surg. 1994;58(2):575–577. DOI: 10.1016/0003-4975(94)92268-3.Schoendube F.A., Klues H.G., Reith S., Messmer B.J. Surgical correction of hypertrophic obstructive cardiomyopathy with combined myectomy, mobilisation and partial excision of the papillary muscles. Eur. J. Cardiothorac. Surg. 1994;8(11):603–608. DOI: 10.1016/1010-7940(94)90044-2.Schoendube F.A., Klues H.G., Reith S., Messmer B.J. Surgical correction of hypertrophic obstructive cardiomyopathy with combined myectomy, mobilisation and partial excision of the papillary muscles. Eur. J. Cardiothorac. Surg. 1994;8(11):603–608. DOI: 10.1016/1010-7940(94)90044-2.Bjork V.O., Hultquist G., Lodin H. Subaortic stenosis produced by an abnormally placed anterior mitral leaflet. J. Thorac. Cardiovasc. Surg. 1961;41(5):659–669. DOI: 10.1016/S0022-5223(20)31663-9.Bjork V.O., Hultquist G., Lodin H. Subaortic stenosis produced by an abnormally placed anterior mitral leaflet. J. Thorac. Cardiovasc. Surg. 1961;41(5):659–669. DOI: 10.1016/S0022-5223(20)31663-9.Pollick C., Morgan C.D., Gilbert B.W., Rakowski H., Wigle E.D. Muscular subaortic stenosis: the temporal relationship between systolic anterior motion of the anterior mitral leaflet and the pressure gradient. Circulation. 1982;66(5):1087– 1094. DOI: 10.1161/01.cir.66.5.1087.Pollick C., Morgan C.D., Gilbert B.W., Rakowski H., Wigle E.D. Muscular subaortic stenosis: the temporal relationship between systolic anterior motion of the anterior mitral leaflet and the pressure gradient. Circulation. 1982;66(5):1087– 1094. DOI: 10.1161/01.cir.66.5.1087.Валиева Л.М., Джорджикия Р.К., Вагизов И.И., Хайруллин Р.Н., Мухарямов М.Н. Хирургическое лечение митральной недостаточности при обструктивной гипертрофической кардиомиопатии. Кардиология и сердечно-сосудистая хирургия. 2020;13(5):396–402. DOI: 10.17116/kardio202013051396.Velieva L.M., Dzhordzhikia R.K., Vagizov II., Khayrullin R.N., Mukharyamov M.N. Surgical treatment of mitral regurgitation in patients with hypertrophic obstructive cardiomyopathy. Kardiologiya I Serdechno-Sosudistaya Khirurgiya. 2020;13(5):396–402. (In Russ.). DOI: 10.17116/kardio202013051396.Krajcer Z., Leachman R.D., Cooley D.A., Coronado R. Septal myotomymyomectomy versus mitral valve replacement in hypertrophic cardiomyopathy. Ten-year follow-up in 185 patients. Circulation. 1989;80(1):157–164.Krajcer Z., Leachman R.D., Cooley D.A., Coronado R. Septal myotomymyomectomy versus mitral valve replacement in hypertrophic cardiomyopathy. Ten-year follow-up in 185 patients. Circulation. 1989;80(1):157–164.Dearani J.A., Danielson G.K. Septal myectomy for obstructive hypertrophic cardiomyopathy. Semin. Thorac. Cardiovasc. Surg. Pediatr. Card. Surg. Annu. 2005;8(1):86–91. DOI: 10.1053/j.pcsu.2005.01.003.Dearani J.A., Danielson G.K. Septal myectomy for obstructive hypertrophic cardiomyopathy. Semin. Thorac. Cardiovasc. Surg. Pediatr. Card. Surg. Annu. 2005;8(1):86–91. DOI: 10.1053/j.pcsu.2005.01.003.Zhu C., Wang S., Ma Y., Wang S., Zhou Z., Yan J. et al. Childhood hypertrophic obstructive cardiomyopathy and its relevant surgical outcome. Ann. Thorac. Surg. 2020;110(1):207–213. DOI: 10.1016/j.athoracsur.2019.10.016.Zhu C., Wang S., Ma Y., Wang S., Zhou Z., Yan J. et al. Childhood hypertrophic obstructive cardiomyopathy and its relevant surgical outcome. Ann. Thorac. Surg. 2020;110(1):207–213. DOI: 10.1016/j.athoracsur.2019.10.016.Dearani J.A., Ommen S.R., Gersh B.J., Schaff H.V., Danielson G.K. Surgery Insight: septal myectomy for obstructive hypertrophic cardiomyopathy – the Mayo Clinic experience. Nat. Clin. Pract. Cardiovasc. Med. 2007;4(9):503–512. DOI: 10.1038/ncpcardio0965.Dearani J.A., Ommen S.R., Gersh B.J., Schaff H.V., Danielson G.K. Surgery Insight: septal myectomy for obstructive hypertrophic cardiomyopathy – the Mayo Clinic experience. Nat. Clin. Pract. Cardiovasc. Med. 2007;4(9):503–512. DOI: 10.1038/ncpcardio0965.

The authors declare that there are no conflicts of interest present.