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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cardiotomsk</journal-id><journal-title-group><journal-title xml:lang="ru">Сибирский журнал клинической и экспериментальной медицины</journal-title><trans-title-group xml:lang="en"><trans-title>Siberian Journal of Clinical and Experimental Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2713-2927</issn><issn pub-type="epub">2713-265X</issn><publisher><publisher-name>TSU publishing</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.29001/2073-8552-2023-39-3-23-31</article-id><article-id custom-type="elpub" pub-id-type="custom">cardiotomsk-1933</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ И ЛЕКЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS AND LECTURES</subject></subj-group></article-categories><title-group><article-title>Возможности денситометрии в оценке диффузных изменений паренхимы легких (обзор литературы)</article-title><trans-title-group xml:lang="en"><trans-title>Possibilities of densitometry in the assessment of diffuse changes in the lung parenchyma</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1117-0294</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сучилова</surname><given-names>М. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Suchilova</surname><given-names>M. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сучилова Мария Максимовна, младший научный сотрудник</p><p>127051, Российская Федерация, Москва, ул. Петровка, 24, стр. 1</p></bio><bio xml:lang="en"><p>Maria M. Suchilova, Junior Research Scientist</p><p>24, Petrovka str., bld. 1, Moscow, 127051, Russian Federation</p></bio><email xlink:type="simple">SuchilovaMM@zdrav.mos.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2681-9378</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Блохин</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Blokhin</surname><given-names>I. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Блохин Иван Андреевич, начальник сектора исследований в лучевой диагностике</p><p>127051, Российская Федерация, Москва, ул. Петровка, 24, стр. 1</p></bio><bio xml:lang="en"><p>Ivan A. Blokhin, Head of the Radiology Research Sector</p><p>24, Petrovka str., bld. 1, Moscow, 127051, Russian Federation</p></bio><email xlink:type="simple">BlokhinIA@zdrav.mos.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0166-3768</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Коденко</surname><given-names>М. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Kodenko</surname><given-names>M. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Коденко Мария Романовна, младший научный сотрудник</p><p>127051, Российская Федерация, Москва, ул. Петровка, 24, стр. 1</p></bio><bio xml:lang="en"><p>Maria R. Kodenko, Junior Research Scientist</p><p>24, Petrovka str., bld. 1, Moscow, 127051, Russian Federation</p></bio><email xlink:type="simple">KodenkoMR@zdrav.mos.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9661-0254</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Решетников</surname><given-names>Р. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Reshetnikov</surname><given-names>R. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Решетников Роман Владимирович, канд. физ.-мат. наук, руководитель отдела научных медицинских исследований</p><p>127051, Российская Федерация, Москва, ул. Петровка, 24, стр. 1</p></bio><bio xml:lang="en"><p>Roman V. Reshetnikov, Cand. Sci. (Phys.-Math.), Head of Medical Research Department</p><p>24, Petrovka str., bld. 1, Moscow, 127051, Russian Federation</p></bio><email xlink:type="simple">r.reshetnikov@npcmr.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5151-4579</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Николаев</surname><given-names>А. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikolaev</surname><given-names>A. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Николаев Александр Евгеньевич, младший научный сотрудник</p><p>127051, Российская Федерация, Москва, ул. Петровка, 24, стр. 1</p></bio><bio xml:lang="en"><p>Alexander E. Nikolaev, Junior Research Scientist</p><p>24, Petrovka str., bld. 1, Moscow, 127051, Russian Federation</p></bio><email xlink:type="simple">NikolaevAE@zdrav.mos.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0245-4431</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Омелянская</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Omelyanskaya</surname><given-names>O. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Омелянская Ольга Васильевна, руководитель по управлению подразделениями Дирекции Наука</p><p>127051, Российская Федерация, Москва, ул. Петровка, 24, стр. 1</p></bio><bio xml:lang="en"><p>Olga V. Omelyanskaya, Head of Division Management of the Directorate of Science </p><p>24, Petrovka str., bld. 1, Moscow, 127051, Russian Federation</p></bio><email xlink:type="simple">o.omelyanskaya@npcmr.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Владзимирский</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Vladzymyrskyy</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Владзимирский Антон Вячеславович, д-р мед. наук, заместитель директора по научной работе; профессор кафедры информационных и интернет-технологий</p><p>0000-0002-2990-7736</p><p>127051, Российская Федерация, Москва, ул. Петровка, 24, стр. 1;119991, Российская Федерация, Москва, ул. Трубецкая, 8, стр. 2</p></bio><bio xml:lang="en"><p>Anton V. Vladzymyrskyy, Dr. Sci. (Med.), Deputy Director for Scientific Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies, Moscow Health Care Department; Professor of the Department of Information and Internet Technologies, I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)</p><p>24, Petrovka str., bld. 1, Moscow, 127051, Russian Federation; 8-2, Trubetskaya str., Moscow, 119991, Russian Federation</p></bio><email xlink:type="simple">VladzimirskijAV@zdrav.mos.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Научно-практический клинический центр диагностики и телемедицинских технологий Департамента здравоохранения города Москвы</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Научно-практический клинический центр диагностики и телемедицинских технологий Департамента здравоохранения города Москвы; Первый Московский государственный медицинский университет имени И.М. Сеченова (Сеченовский Университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department; I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>10</day><month>10</month><year>2023</year></pub-date><volume>38</volume><issue>3</issue><fpage>23</fpage><lpage>31</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Сучилова М.М., Блохин И.А., Коденко М.Р., Решетников Р.В., Николаев А.Е., Омелянская О.В., Владзимирский А.В., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Сучилова М.М., Блохин И.А., Коденко М.Р., Решетников Р.В., Николаев А.Е., Омелянская О.В., Владзимирский А.В.</copyright-holder><copyright-holder xml:lang="en">Suchilova M.M., Blokhin I.A., Kodenko M.R., Reshetnikov R.V., Nikolaev A.E., Omelyanskaya O.V., Vladzymyrskyy A.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.sibjcem.ru/jour/article/view/1933">https://www.sibjcem.ru/jour/article/view/1933</self-uri><abstract><p>Данные, полученные при проведении компьютерной томографии (КТ) органов грудной клетки, можно проанализировать не только визуально, но и численно. Количественная оценка позволяет более точно и объективно оценить степень тяжести заболевания. Наиболее изученным способом количественной оценки данных КТ является денситометрия – автоматический анализ плотностных показателей легких, выраженных в единицах Хаунсфилда. Данный обзор посвящен типам заболеваний, для которых возможна формализация диагностической задачи и применение денситометрии, а также ограничениям метода и способам их преодоления.</p></abstract><trans-abstract xml:lang="en"><p>The data obtained from chest computed tomography (CT) can be analyzed not only visually, but also quantitatively. Quantitative assessment allows a more accurate and objective evaluation of the disease severity. Densitometry is the most researched way to quantify CT data – automatic analysis of lung densities expressed in Hounsfield units. This review is focused on the types of diseases that can be characterized by the formalization of the diagnostic task and application of densitometry, as well as on the limitations of the method and the ways to cope with them.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>денситометрия</kwd><kwd>компьютерная томография</kwd><kwd>низкодозная компьютерная томография</kwd></kwd-group><kwd-group xml:lang="en"><kwd>densitometry</kwd><kwd>computed tomography</kwd><kwd>low-dose computed tomography</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Данная статья подготовлена авторским коллективом в рамках НИР «Научное обоснование методов лучевой диагностики опухолевых заболеваний с использованием радиомического анализа», (№ ЕГИСУ: № 123031500005-2) в соответствии с Приказом от 21.12.2022 г. № 1196 «Об утверждении государственных заданий, финансовое обеспечение которых осуществляется за счет средств бюджета города Москвы государственным бюджетным (автономным) учреждениям подведомственным Департаменту здравоохранения города Москвы, на 2023 год и плановый период 2024 и 2025 годов» Департамента здравоохранения города Москвы.</funding-statement><funding-statement xml:lang="en">This paper was prepared by a group of authors as a part of the research and development effort titled “Scientific evidence for using radiomics-guided medical imaging to diagnose cancer”, No. 123031400009-1”, (USIS No. 123031500005-2) in accordance with the Order No. 1196 dated December 21, 2022 «On approval of state assignments funded by means of allocations from the budget of the city of Moscow to the state budgetary (autonomous) institutions subordinate to the Moscow Health Care Department, for 2023 and the planned period of 2024 and 2025» issued by the Moscow Health Care Department.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Mascalchi M., Diciotti S., Sverzellati N., Camiciottoli G., Ciccotosto C., Falaschi F. et al. 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