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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cardiotomsk</journal-id><journal-title-group><journal-title xml:lang="ru">Сибирский журнал клинической и экспериментальной медицины</journal-title><trans-title-group xml:lang="en"><trans-title>Siberian Journal of Clinical and Experimental Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2713-2927</issn><issn pub-type="epub">2713-265X</issn><publisher><publisher-name>TSU publishing</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.29001/2073-8552-2023-38-4-213-221</article-id><article-id custom-type="elpub" pub-id-type="custom">cardiotomsk-2070</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL STUDIES</subject></subj-group></article-categories><title-group><article-title>Факторы, определяющие качество жизни у пациентов с ишемической болезнью сердца, которым планируется операция аортокоронарного шунтирования</article-title><trans-title-group xml:lang="en"><trans-title>Factors associated with quality of life in patients with coronary artery disease before coronary artery bypass surgery</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0003-0468-1675</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Асадуллин</surname><given-names>И. Ш.</given-names></name><name name-style="western" xml:lang="en"><surname>Asadullin</surname><given-names>I. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Асадуллин Ильшат Шамилевич, сердечно-сосудистый хирург, кардиохирургическое отделение с кабинетом рентгенэндоваскулярных диагностики и лечения</p><p>190005, Санкт-Петербург, наб. реки Фонтанки, 154</p></bio><bio xml:lang="en"><p>Ilshat S. Asadullin, Cardiovascular Surgeon, Cardiac Surgery Department with the X-ray Endovascular Diagnostic and Treatment Room</p><p>195005, Fontanka riv. embankment, 154, Saint-Petersburg</p><p> </p></bio><email xlink:type="simple">ilshat-asadullin@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2267-2580</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Каменских</surname><given-names>М. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Kamenskikh</surname><given-names>M. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Каменских Максим Сергеевич, канд. мед. наук, заведующий кардиохирургическим отделением с кабинетом рентгенэндоваскулярных диагностики и лечения, врач сердечно-сосудистый хирург </p><p>190005, Санкт-Петербург, наб. реки Фонтанки, 154</p></bio><bio xml:lang="en"><p>Maxim S. Kamenskikh, Cand. Sci. (Med.), Head of the Cardiac Surgery Department with the X-ray Endovascular Diagnostic and Treatment Room </p><p>195005, Fontanka riv. embankment, 154, Saint-Petersburg</p></bio><email xlink:type="simple">kamen-maksim@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3338-9855</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Филиппов</surname><given-names>A. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Philippov</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Филиппов Алексей Александрович, канд. мед. наук, сердечно-сосудистый хирург, кардиохирургическое отделение с кабинетом рентгенэндоваскулярных диагностики и лечения </p><p>190005, Санкт-Петербург, наб. реки Фонтанки, 154</p></bio><bio xml:lang="en"><p>Alexey A. Philippov, Cand. Sci. (Med.), Cardiac Surgeon, Department with the X-ray Endovascular Diagnostic and Treatment Room </p><p>195005, Fontanka riv. embankment, 154, Saint-Petersburg</p></bio><email xlink:type="simple">kaptain_alex@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5581-9169</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ефремов</surname><given-names>С. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Efremov</surname><given-names>S. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ефремов Сергей Михайлович, д-р мед. наук, профессор, заместитель директора по научной деятельности</p><p>190005, Санкт-Петербург, наб. реки Фонтанки, 154</p></bio><bio xml:lang="en"><p>Sergey M. Efremov, Dr. Sci. (Med.), Deputy Director for Scientific Activities </p><p>195005, Fontanka riv. embankment, 154, Saint-Petersburg</p></bio><email xlink:type="simple">sergefremov@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8279-8129</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Никитина</surname><given-names>Т. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikitina</surname><given-names>T. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Никитина Татьяна Павловна, канд. мед. наук, врач-методист, отдел мониторинга качества жизни</p><p>190005, Санкт-Петербург, наб. реки Фонтанки, 154</p></bio><bio xml:lang="en"><p>Tatiana P. Nikitina, Cand. Sci. (Med.), Public Health Specialist, Department of Quality of Life Monitoring </p><p>195005, Fontanka riv. embankment, 154, Saint-Petersburg</p></bio><email xlink:type="simple">tnikitina_74@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9431-5286</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ионова</surname><given-names>Т. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Ionova</surname><given-names>T. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ионова Татьяна Ивановна, д-р биол. наук, профессор, руководи- тель отдела мониторинга качества жизни</p><p>190005, Санкт-Петербург, наб. реки Фонтанки, 154</p></bio><bio xml:lang="en"><p>Tatiana I. Ionova, Dr. Sci. (Biol.), Professor, Head of the Department of Quality of Life Monitoring </p><p>195005, Fontanka riv. embankment, 154, Saint-Petersburg</p></bio><email xlink:type="simple">tation16@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1296-8161</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шматов</surname><given-names>Д. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shmatov</surname><given-names>D. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шматов Дмитрий Викторович, д-р мед. наук, профессор, заместитель директора по медицинской части (кардиохирургия)</p><p>190005, Санкт-Петербург, наб. реки Фонтанки, 154</p></bio><bio xml:lang="en"><p>Dmitry V. Shmatov, Dr. Sci. (Med.), Professor, Deputy Director for Medical Affairs (Cardiac Surgery) </p><p>195005, Fontanka riv. embankment, 154, Saint-Petersburg</p></bio><email xlink:type="simple">dv.shmatov@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Клиника высоких медицинских технологий имени Н.И. Пирогова Санкт-Петербургского государственного университета<country>Россия</country></aff><aff xml:lang="en">Saint Petersburg State University Hospital<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>14</day><month>01</month><year>2024</year></pub-date><volume>38</volume><issue>4</issue><fpage>213</fpage><lpage>221</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Асадуллин И.Ш., Каменских М.С., Филиппов A.А., Ефремов С.М., Никитина Т.П., Ионова Т.И., Шматов Д.В., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Асадуллин И.Ш., Каменских М.С., Филиппов A.А., Ефремов С.М., Никитина Т.П., Ионова Т.И., Шматов Д.В.</copyright-holder><copyright-holder xml:lang="en">Asadullin I.S., Kamenskikh M.S., Philippov A.A., Efremov S.M., Nikitina T.P., Ionova T.I., Shmatov D.V.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.sibjcem.ru/jour/article/view/2070">https://www.sibjcem.ru/jour/article/view/2070</self-uri><abstract><sec><title>Обоснование</title><p>Обоснование. Результаты аортокоронарного шунтирования (АКШ) при ишемической болезни сердца (ИБС) зависят от ряда факторов, в том числе от исходного качества жизни пациента.</p></sec><sec><title>Цель исследования</title><p>Цель исследования: изучение качества жизни и связанных с ним факторов у больных ИБС до АКШ.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. В одноцентровом наблюдательном исследовании участвовали больные ИБС, которые поступали на лечение для проведения плановой операции АКШ. Всем пациентам проведена оценка качества жизни с использованием общего опросника SF-36 и специального опросника SAQ. Статистические методы включали параметрические и непараметрические критерии и множественную логистическую регрессию.</p></sec><sec><title>Результаты</title><p>Результаты. В исследование включены 240 больных ИБС (медиана возраста 65 лет, мужчины – 69%). Больше половины больных до АКШ имели плохое физическое и психологическое здоровье. Самые низкие показатели зарегистрированы по шкалам физических ограничений и восприятия болезни, а также ролевому функционированию. Показатели качества жизни хуже у женщин, пациентов ≥ 65 лет, с ожирением, коморбидностью, длительным течением ИБС, не работающих и проживающих в малонаселенных пунктах (p &lt; 0,05). Предикторы плохого качества жизни – женский пол (ОШ 2,574; 95% ДИ ОШ 1,335–4,961; p = 0,005), ожирение (ОШ 1,984; 95% ДИ ОШ 1,075–3,663; p = 0,028) и длительное течение ИБС (ОШ 1,006; 95% ДИ ОШ 1,002–1,010; p = 0,006). Предикторы плохого физического здоровья – возраст ≥ 65 лет (ОШ 0,823; 95% ДИ ОШ 0,430–1,576; p = 0,001), ожирение (ОШ 2,050; 95% ДИ ОШ 1,041–4,039; p = 0,038) и длительное течение ИБС (ОШ 1,005; 95% ДИ ОШ 1,001–1,010; p = 0,027). Предикторы плохого психического здоровья – возраст ≥ 65 лет (ОШ 1,973; 95% ДИ ОШ 1,050–3,706; p = 0,035) и проживание в малонаселенном пункте (ОШ 2,213; 95% ДИ ОШ 1,236–3,962; p = 0,008).</p></sec><sec><title>Заключение</title><p>Заключение. Предикторами плохого качества жизни больных ИБС перед АКШ являются женский пол, возраст ≥ 65 лет, ожирение, длительный стаж заболевания и проживание в малонаселенных пунктах.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Relevance</title><p>Relevance. The outcomes of coronary artery bypass surgery (CABG) for coronary artery disease (CAD) depend on different factors, including patient’s quality of life (QoL) before CABG.</p></sec><sec><title>Aim</title><p>Aim: To study QoL and associated factors in CAD patients before CABG.</p></sec><sec><title>Material and Methods</title><p>Material and Methods. A single-center observational study involved CAD patients who were admitted for elective CABG. All patients completed generic quality of life questionnaire SF-36 and specific questionnaire SAQ. Statistical methods included parametric and non-parametric comparisons and multiple regression analysis.</p></sec><sec><title>Results</title><p>Results. The study included 240 CAD patients (median age 65 years, males – 69%). More than half of the patients had poor physical and psychological health before CABG. Physical limitations and perception of the disease as well as role functioning were most impaired. QoL was worse in women, older patients, with obesity, comorbidity, long-lasting CAD, non-workers and living in sparsely populated areas (p &lt; 0.05). Predictors of poor QoL – female gender (OR 2.574, 95% CI 1.335–4.961; p = 0.005), obesity (OR 1.984, 95% CI 1.075–3.663; p = 0.028) and long–term CAD (OR 1.006, 95% CI 1.002‒0.010; p = 0.006). Predictors of poor physical health – age ≥ 65 (OR 0,823, 95% CI 0.430–1.576; p = 0.001), obesity (OR 2,050, 95% CI 1.041–4.039; p = 0.038) and long–term CAD (OR 1.005, 95% CI 1.001–1.010; p = 0.027). Predictors of poor mental health – age ≥ 65 (OR 1.973, 95% CI 1.050–3.706; p = 0.035) and living in sparsely populated areas (OR 2.213, 95% CI 1.236–3.962; p = 0.008).</p></sec><sec><title>Conclusion</title><p>Conclusion. Predictors of poor QoL before CABG are female gender, elderly age, obesity, long-term CAD and living in sparsely populated areas.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>качество жизни</kwd><kwd>ишемическая болезнь сердца</kwd><kwd>аортокоронарное шунтирование</kwd><kwd>SAQ</kwd><kwd>SF36</kwd><kwd>предикторы</kwd></kwd-group><kwd-group xml:lang="en"><kwd>quality of life</kwd><kwd>coronary artery disease</kwd><kwd>coronary artery bypass surgery</kwd><kwd>SAQ questionnaire</kwd><kwd>SF-36 questionnaire</kwd><kwd>predictors</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">WHO (World Health Organization). 2020. The top 10 causes of death. Geneva: WHO. [Electronic resource]. URL: https://www.who.int/news-room/fact-sheets/detail/the-top-10-causes-of-death (23.11.2023).</mixed-citation><mixed-citation xml:lang="en">WHO (World Health Organization). 2020. 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