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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cardiotomsk</journal-id><journal-title-group><journal-title xml:lang="ru">Сибирский журнал клинической и экспериментальной медицины</journal-title><trans-title-group xml:lang="en"><trans-title>Siberian Journal of Clinical and Experimental Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2713-2927</issn><issn pub-type="epub">2713-265X</issn><publisher><publisher-name>TSU publishing</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.29001/2073-8552-2025-40-2-142-149</article-id><article-id custom-type="elpub" pub-id-type="custom">cardiotomsk-2740</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ СЛУЧАИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL CASES</subject></subj-group></article-categories><title-group><article-title>Клинический опыт применения костной крошки для улучшения регенерации костной ткани грудины после срединной стернотомии у пациентов с высоким риском стернальной дегисценции в кардиохирургической практике</article-title><trans-title-group xml:lang="en"><trans-title>Use of bone chips to improve sternum bone tissue regeneration after median sternotomy in patients with a high risk of sternal dehiscence in cardiac surgery (case report)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1975-043X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кузнецов</surname><given-names>М. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Kuznetsov</surname><given-names>M. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кузнецов Михаил Сергеевич, канд. мед. наук, научный сотрудник, отделение сердечно-сосудистой хирургии</p><p>634012, Томск, ул. Киевская, 111а</p></bio><bio xml:lang="en"><p>Mikhail S. Kuznetsov, Cand. Sci. (Med.), Research Scientist, Department of Cardiovascular Surgery</p><p>111a, Kievskaya str., Tomsk, 634012</p></bio><email xlink:type="simple">kms@cardio-tomsk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2758-7107</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ахмедов</surname><given-names>Ш. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Akhmedov</surname><given-names>Sh. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ахмедов Шамиль Джаманович, д-р мед. наук, профессор, ведущий научный сотрудник, отделение сердечно-сосудистой хирургии</p><p>634012, Томск, ул. Киевская, 111а</p></bio><bio xml:lang="en"><p>Shamil D. Akhmedov, Dr. Sci. (Med.), Professor, Leading Research Scientist, Department of Cardiovascular Surgery</p><p>111a, Kievskaya str., Tomsk, 634012</p></bio><email xlink:type="simple">shamil@cardio-tomsk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9887-8214</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шипулин</surname><given-names>В. B.</given-names></name><name name-style="western" xml:lang="en"><surname>Shipulin</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шипулин Владимир Владимирович, канд. мед. наук, научный сотрудник, лаборатория радионуклидных методов исследования</p><p>634012, Томск, ул. Киевская, 111а</p></bio><bio xml:lang="en"><p>Vladimir V. Shipulin, Research Scientist, Laboratory of Radionuclide Research Methods</p><p>111a, Kievskaya str., Tomsk, 634012</p></bio><email xlink:type="simple">shipartphoto@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6593-0976</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алямкин</surname><given-names>В. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Alyamkin</surname><given-names>V. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Алямкин Вадим Евгеньевич, клинический ординатор,  отделение сердечно-сосудистой хирургии</p><p>634012, Томск, ул. Киевская, 111а</p></bio><bio xml:lang="en"><p>Vadim E. Alyamkin, Medical Resident, Department of Cardiovascular Surgery</p><p>111a, Kievskaya str., Tomsk, 634012</p></bio><email xlink:type="simple">vea@cardio-tomsk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9466-6097</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Буховец</surname><given-names>И. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Bukhovets</surname><given-names>I. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Буховец Ирина Львовна, д-р мед. наук, старший научный сотрудник, отделение рентгеновских и томографических методов диагностики</p><p>634012, Томск, ул. Киевская, 111а</p></bio><bio xml:lang="en"><p>Irina L. Bukhovets, Dr. Sci. (Med.), Senior Research Scientist, Department of X-ray and Tomographic Diagnostic Methods</p><p>111a, Kievskaya str., Tomsk, 634012</p><p> </p></bio><email xlink:type="simple">bil@cardio-tomsk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3147-3025</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гусакова</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Gusakova</surname><given-names>A. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гусакова Анна Михайловна, канд. фарм. наук, старший научный сотрудник, отделение функциональной и лабораторной диагностики</p><p>634012, Томск, ул. Киевская, 111а</p></bio><bio xml:lang="en"><p>Anna M. Gusakova, Cand. Sci. (Pharm.), Senior Research Scientist, Department of Functional and Laboratory Diagnostics</p><p>111a, Kievskaya str., Tomsk, 634012</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5471-7566</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Афанасьева</surname><given-names>Н. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Afanasyeva</surname><given-names>N. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Афанасьева Наталья Леонидовна, канд. мед. наук, врач-кардиолог, отделение сердечно-сосудистой хирургии</p><p>634012, Томск, ул. Киевская, 111а</p></bio><bio xml:lang="en"><p>Natalia L. Afanasyeva, Cand.  Sci.  (Med.),  Cardiologist,  Department of Cardiovascular Surgery</p><p>111a, Kievskaya str., Tomsk, 634012</p></bio><email xlink:type="simple">fnatalko@cardio-tomsk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0217-7737</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Козлов</surname><given-names>Б. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Kozlov</surname><given-names>B. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Козлов Борис Николаевич, д-р мед. наук, заведующий отделением сердечно-сосудистой хирургии</p><p>634012, Томск, ул. Киевская, 111а</p></bio><bio xml:lang="en"><p>Boris N. Kozlov, Dr. Sci. (Med.), Head of the Department of Cardiovascular Surgery</p><p>111a, Kievskaya str., Tomsk, 634012</p></bio><email xlink:type="simple">bnkozlov@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Научно-исследовательский институт кардиологии, Томский национальный исследовательский медицинский центр Российской академии наук</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Research Institute of Cardiology, Tomsk National Research Medical Center of the Russian Academy of Sciences</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>13</day><month>07</month><year>2025</year></pub-date><volume>40</volume><issue>2</issue><fpage>142</fpage><lpage>149</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Кузнецов М.С., Ахмедов Ш.Д., Шипулин В.B., Алямкин В.Е., Буховец И.Л., Гусакова А.М., Афанасьева Н.Л., Козлов Б.Н., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Кузнецов М.С., Ахмедов Ш.Д., Шипулин В.B., Алямкин В.Е., Буховец И.Л., Гусакова А.М., Афанасьева Н.Л., Козлов Б.Н.</copyright-holder><copyright-holder xml:lang="en">Kuznetsov M.S., Akhmedov S.D., Shipulin V.V., Alyamkin V.E., Bukhovets I.L., Gusakova A.M., Afanasyeva N.L., Kozlov B.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.sibjcem.ru/jour/article/view/2740">https://www.sibjcem.ru/jour/article/view/2740</self-uri><abstract><p>Срединная стернотомия остается доступом выбора при операциях на сердце, магистральных сосудах и операциях на легких. Согласно анализу публикаций по данной тематике, такие послеоперационные осложнения после срединной стернотомии, как несостоятельность швов грудины, острый медиастинит и остеомиелит грудины и ребер формируются у 2–6% пациентов. В статье рассматривается клинический случай успешного применения новой методики, направленной на ускорение процессов регенерации костной ткани грудины с использованием костно-пластического материала у пациента группы высокого риска стернальной дегисценции. Эффективность данной методики открывает возможность ее широкого внедрения в клиническую практику.</p></abstract><trans-abstract xml:lang="en"><p>Median sternotomy remains the approach of choice for cardiac, great vessel, and pulmonary surgeries. According to data analysis, postoperative complications after median sternotomy, such as incompetence of the sternal sutures, acute mediastinitis and osteomyelitis of the sternum and ribs, occur in 2–6% of patients. The article discusses a clinical case of the successful use of a new technique aimed at accelerating the processes of regeneration of sternum bone tissue using osteoplastic material in a patient at high risk of sternal dehiscence. The effectiveness of this technique opens up the possibility of its widespread implementation in clinical practice.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>стернотомия</kwd><kwd>костно-пластические материалы</kwd><kwd>дегисценция грудины</kwd><kwd>диастаз грудины</kwd><kwd>клинический случай</kwd></kwd-group><kwd-group xml:lang="en"><kwd>sternotomy</kwd><kwd>osteoplastic materials</kwd><kwd>sternal dehiscence</kwd><kwd>sternal diastasis</kwd><kwd>clinical case</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Hernández-Zamora R.E., Sotelo-Carbajal J., Martínez-Maya G., García-Ledezma A., Román-Matus A., Torres-Salazar Q.L. 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