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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cardiotomsk</journal-id><journal-title-group><journal-title xml:lang="ru">Сибирский журнал клинической и экспериментальной медицины</journal-title><trans-title-group xml:lang="en"><trans-title>Siberian Journal of Clinical and Experimental Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2713-2927</issn><issn pub-type="epub">2713-265X</issn><publisher><publisher-name>TSU publishing</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.29001/2073-8552-2025-40-2-211-217</article-id><article-id custom-type="elpub" pub-id-type="custom">cardiotomsk-2746</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЦИФРОВЫЕ ТЕХНОЛОГИИ В МЕДИЦИНЕ И ЗДРАВООХРАНЕНИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>DIGITAL TECHNOLOGIES IN MEDICINE AND HEALTHCARE</subject></subj-group></article-categories><title-group><article-title>Применение искусственного интеллекта в патологической анатомии</article-title><trans-title-group xml:lang="en"><trans-title>Application of artificial intelligence in pathology</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6578-0050</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Швороб</surname><given-names>Д. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Shvorob</surname><given-names>D. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Швороб Данил Сергеевич, ассистент, кафедра патологической анатомии</p><p> </p><p>283001, Донецкая Народная Республика, Донецк, ул. Артема, 58</p></bio><bio xml:lang="en"><p>Danil S. Shvorob, Assistant Professor, Pathological Anatomy Department</p><p>16, Il’icha ave., Donetsk, 283003, Donetsk People's Republic</p></bio><email xlink:type="simple">mcshady@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9362-2279</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Васяева</surname><given-names>Т. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Vasyaeva</surname><given-names>T. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Васяева Татьяна Александровна, канд. техн. наук, доцент, декан факультета информационных систем и технологий</p><p>283003, Донецкая Народная Республика, Донецк, пр. Ильича, 16</p></bio><bio xml:lang="en"><p>Tatyana A. Vasyaeva, Ph.D. in Engineering, Associate Professor, Dean of the Faculty</p><p>58, Artema str., Donetsk, 283001, Donetsk People's Republic</p></bio><email xlink:type="simple">vasyaeva@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0001-2070-2371</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хрюкин</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Khriukin</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Хрюкин Евгений Александрович, аспирант, кафедра автоматизированных систем управления</p><p>283003, Донецкая Народная Республика, Донецк, пр. Ильича, 16</p></bio><bio xml:lang="en"><p>Evgeniy A. Khriukin, Graduate Student, Automated Control Systems Department </p><p>58, Artema str., Donetsk, 283001, Donetsk People's Republic</p></bio><email xlink:type="simple">wadealer@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0004-6166-0288</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Папакина</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Papakina</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Папакина Анна Владимировна, студент 6-го курса</p><p>283001, Донецкая Народная Республика, Донецк, ул. Артема, 58</p></bio><bio xml:lang="en"><p>Anna V. Papakina, 6th-year student</p><p>16, Il’icha ave., Donetsk, 283003, Donetsk People's Republic</p></bio><email xlink:type="simple">annapapakina6@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Донецкий государственный медицинский университет имени М. Горького</institution><country>Россия</country></aff><aff xml:lang="en"><institution>M. Gorky Donetsk State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Донецкий национальный технический университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Donetsk National Technical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>13</day><month>07</month><year>2025</year></pub-date><volume>40</volume><issue>2</issue><fpage>211</fpage><lpage>217</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Швороб Д.С., Васяева Т.А., Хрюкин Е.А., Папакина А.В., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Швороб Д.С., Васяева Т.А., Хрюкин Е.А., Папакина А.В.</copyright-holder><copyright-holder xml:lang="en">Shvorob D.S., Vasyaeva T.A., Khriukin E.A., Papakina A.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.sibjcem.ru/jour/article/view/2746">https://www.sibjcem.ru/jour/article/view/2746</self-uri><abstract><p>Развитие цифровых технологий и алгоритмов компьютерного зрения расширяет возможности использования искусственного интеллекта (ИИ) в патологической анатомии. Нейросети, основанные на глубоком обучении (ГО), успешно разрабатываются и применяются для выполнения задач, связанных с диагностикой и классификацией опухолей, идентификацией иммуногистохимических маркеров, морфометрии. Применение ИИ не только способствует объективизации диагностического процесса, но и снижает нагрузку на врача-патологоанатома, позволяя концентрироваться на более сложных случаях. Несмотря на это, существуют ограничения внедрения нейросетей в рутинную патологоанатомическую практику, включающие финансовые и юридические трудности, а также недоверчивое отношение к автоматической диагностике у врачей и пациентов. В обзоре литературы представлена информация об ИИ, машинном обучении (МО) и архитектурах нейросетей, а также об их интеграции в практику врача-патологоанатома. Перечислены программные продукты, использующиеся для количественных морфологических исследований, диагностики и прогнозирования заболеваний. Совокупность разработанных программ на основе ИИ указывает на значительный интерес и актуальность их использования в патологоанатомической практике и открывает новые границы в персонифицированной медицине.</p><p> </p></abstract><trans-abstract xml:lang="en"><p>The development of digital technologies and computer vision algorithms extends the possibilities of Artificial Intelligence application in pathology. Neural networks based on deep learning are being successfully developed and used to perform tasks related to the diagnosis and classification of tumors, identification of immunohistochemical markers and morphometry. The use of Artificial Intelligence not only contributes to the objectification of the diagnostic process, but also reduces the burden on the pathologists, allowing them to concentrate on more complex cases. Despite this, there are limitations to the introduction of neural networks into routine pathology practice, including financial and legal difficulties, as well as a distrustful attitude towards automatic diagnosis among doctors and patients. The literature review provides information on Artificial Intelligence, machine learning and neural network architecture, as well as their integration into the practice of a pathologist. The software products used for quantitative morphological studies, diagnosis and prognosis of diseases are listed. The set of developed AI-based programs indicates a significant interest and relevance of their use in pathological and anatomical practice and opens new frontiers in personalized medicine.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>нейронная сеть</kwd><kwd>искусственный интеллект</kwd><kwd>патологическая анатомия</kwd><kwd>полнослайдовые изображения</kwd><kwd>морфологическое исследование</kwd></kwd-group><kwd-group xml:lang="en"><kwd>neural network</kwd><kwd>artificial intelligence</kwd><kwd>pathology</kwd><kwd>whole slide imaging</kwd><kwd>morphological research</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Hunter B., Hindocha S., Lee R.W. The role of artificial intelligence in early cancer diagnosis. Cancers (Basel). 2022;14(6):1524. https://doi.org/10.3390/cancers14061524</mixed-citation><mixed-citation xml:lang="en">Hunter B., Hindocha S., Lee R.W. 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