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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cardiotomsk</journal-id><journal-title-group><journal-title xml:lang="ru">Сибирский журнал клинической и экспериментальной медицины</journal-title><trans-title-group xml:lang="en"><trans-title>Siberian Journal of Clinical and Experimental Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2713-2927</issn><issn pub-type="epub">2713-265X</issn><publisher><publisher-name>TSU publishing</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.29001/2073-8552-2018-33-4-69-75</article-id><article-id custom-type="elpub" pub-id-type="custom">cardiotomsk-613</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL STUDIES</subject></subj-group></article-categories><title-group><article-title>СРАВНИТЕЛЬНЫЙ АНАЛИЗ ДЕМОГРАФИЧЕСКИХ, АНАМНЕСТИЧЕСКИХ, КЛИНИКО-ЛАБОРАТОРНЫХ И ИНСТРУМЕНТАЛЬНЫХ ДАННЫХ У ПАЦИЕНТОВ С ИНФАРКТОМ МИОКАРДА С ОБСТРУКТИВНЫМ ПОРАЖЕНИЕМ И БЕЗ ОБСТРУКТИВНОГО ПОРАЖЕНИЯ КОРОНАРНЫХ АРТЕРИЙ</article-title><trans-title-group xml:lang="en"><trans-title>COMPARATIVE ANALYSIS OF DEMOGRAPHIC, ANAMNESTIC, CLINICAL-LABORATORY AND INSTRUMENTAL DATA IN PATIENTS WITH MYOCARDIAL INFARCTION WITH AND WITHOUT OBSTRUCTIVE LESION OF CORONARY ARTERIES</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кручинова</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kruchinova</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>аспирант кафедры терапии № 1 ФПК и ППС, врач-кардиолог</p><p>350068, Российская Федерация, Краснодар, ул. 1 Мая, 167</p><p>350063, Российская Федерация, Краснодар, ул. М. Седина, 4</p></bio><bio xml:lang="en"><p>Postgraduate Student, Department of Therapy No. 1, Cardiologist</p><p>167, May 1 str., Krasnodar, 350068, Russian Federation</p><p>4, M. Sedina str., Krasnodar, 350063, Russian Federation</p></bio><email xlink:type="simple">skruchinova@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Космачева</surname><given-names>Е. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Kosmacheva</surname><given-names>E. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук, профессор, заместитель главного врача по медицинской части, </p><p>заведующая кафедрой терапии № 1 ФПК и ППС</p><p>350068, Российская Федерация, Краснодар, ул. 1 Мая, 167</p><p>350063, Российская Федерация, Краснодар, ул. М. Седина, 4</p></bio><bio xml:lang="en"><p>Dr. Sci. (Med.), Professor, Deputy Chief Physician, </p><p>Head of the Department of Therapy No. 1</p><p>167, May 1 str., Krasnodar, 350068, Russian Federation</p><p>4, M. Sedina str., Krasnodar, 350063, Russian Federation</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Порханов</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Porkhanov</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук, академик РАН, главный врач</p><p>350068, Российская Федерация, Краснодар, ул. 1 Мая, 167</p></bio><bio xml:lang="en"><p>Dr. Sci. (Med.), Full Member of the Russian Academy of Sciences, Chief Physician</p><p>167, May 1 str., Krasnodar, 350068, Russian Federation</p><p> </p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Научно-исследовательский институт — Краевая клиническая больница № 1 имени профессора С. В. Очаповского,&#13;
Кубанский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Scientific Research Institution — Regional Clinical Hospital No. 1 named after Professor S. V. Ochapovsky&#13;
Kuban State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Научно-исследовательский институт — Краевая клиническая больница № 1 имени профессора С. В. Очаповского</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Scientific Research Institution — Regional Clinical Hospital No. 1 named after Professor S. V. Ochapovsky</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>13</day><month>02</month><year>2019</year></pub-date><volume>33</volume><issue>4</issue><fpage>69</fpage><lpage>75</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Кручинова С.В., Космачева Е.Д., Порханов В.А., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Кручинова С.В., Космачева Е.Д., Порханов В.А.</copyright-holder><copyright-holder xml:lang="en">Kruchinova S.V., Kosmacheva E.D., Porkhanov V.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.sibjcem.ru/jour/article/view/613">https://www.sibjcem.ru/jour/article/view/613</self-uri><abstract><p>Цель: дать сравнительную характеристику инфаркту миокарда у пациентов с обструктивным поражением и без обструктивного поражения коронарных артерий.Материал и методы. В исследовании приняли участие 4639 пациентов, включенных в первый тотальный регистр острого коронарного синдрома по Краснодарскому краю за первые 12 мес. ведения. Проведен сравнительный анализ пациентов с инфарктом миокарда с обструктивным поражением и без обструктивного поражения коронарных артерий.Результаты. За период с ноября 2016 по ноябрь 2017 г. в регистр были включены 4453 пациента с инфарктом миокарда с обструктивным поражением коронарного русла, в том числе 2261 мужчина (50,8%) и 2192 женщины (49,2%). Средний возраст больных составлял 68,3±12,03 года, у мужчин — 69,3±3,42; у женщин — 63,4±7,35 года. Критериям инфаркта миокарда без обструктивного поражения коронарных артерий соответствовали 186 человек (4,1%), в том числе 72 мужчин (38,7%) и 114 женщин (72,3%). Средний возраст пациентов составил 54,2±4,53 года, у мужчин с инфарктом миокарда без обструктивного поражения коронарных артерий — 56,3±3,52; у женщин — 52,1±3,12 года. В статье представлен подробный сравнительный анализ демографических, анамнестических, клинико-инструментальных, лабораторных данных групп пациентов.Выводы. По сравнению с пациентами, имевшими обструктивные коронарные изменения, контингент пациентов с инфарктом миокарда без обструктивного поражения коронарных артерий моложе, превалируют женщины, из факторов риска в этой группе значительную роль сыграли курение, артериальная гипертензия, чаще встречался впервые выявленный сахарный диабет, Q-позитивный инфаркт миокарда. По данным эхокардиографии достоверно реже наблюдалось значимое снижение глобальной сократимости миокарда левого желудочка; при анализе лабораторных показателей было отмечено, что у пациентов чаще наблюдалась тромбоцитопения.</p></abstract><trans-abstract xml:lang="en"><sec><title>Objective</title><p>Objective: to give a comparative characterization of myocardial infarction with and without obstructive lesion of coronary arteries.</p></sec><sec><title>Material and Methods</title><p>Material and Methods. The study involved 4639 patients included in the first total register of acute coronary syndrome in the Krasnodar Territory for the first 12 months of register operation. A comparative analysis of patients with myocardial infarction with obstructive lesion and without obstructive lesion of coronary arteries was performed.</p></sec><sec><title>Results</title><p>Results. Between November 2016 and November 2017, 4453 patients with myocardial infarction with obstructive coronary disease, including 2261 men (50.8%) and 2192 women (49.2%) were enrolled in the register. The mean age of patients was 68.3±12.03 years (69.3±3.42 years in men; 63.4±7.35 years in women). The criteria for myocardial infarction without obstructive coronary artery disease were present in 186 people (4.1%), including 72 men (38.7%) and 114 women (72.3%). The average age of the patients was 54.2±4.53 years; age of men with myocardial infarction without obstructive coronary disease was 56.3±3.52 years; age of women was 52.1±3.12 years. The article presents a detailed comparative analysis of demographic, medical history, clinical-instrumental, and laboratory data of these patient groups. </p></sec><sec><title>Conclusion</title><p>Conclusion. Compared with patients who had obstructive coronary changes, the cohort of patients with myocardial infarction without obstructive lesions of the coronary arteries was younger and included more female patients; among the risk factors in this group, smoking and arterial hypertension were significant; the rates of newly diagnosed diabetes mellitus and Q-positive myocardial infarction were higher. According to the analysis of echocardiographic data, significant decrease in global contractility of the left ventricular myocardium was less common; analysis of laboratory data showed that patients more often had low platelet count.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>инфаркт миокарда без обструктивного поражения коронарных артерий</kwd><kwd>регистр</kwd></kwd-group><kwd-group xml:lang="en"><kwd>myocardial infarction without obstructive coronary artery disease</kwd><kwd>register</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Erlih A. D., Gracianskij N. A. Registers of acute coronary syndromes — their types, characteristics and location in clinical practice. Kardiologiya. 2011; 12: 18–23.</mixed-citation><mixed-citation xml:lang="en">Erlih A. D., Gracianskij N. 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