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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cardiotomsk</journal-id><journal-title-group><journal-title xml:lang="ru">Сибирский журнал клинической и экспериментальной медицины</journal-title><trans-title-group xml:lang="en"><trans-title>Siberian Journal of Clinical and Experimental Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2713-2927</issn><issn pub-type="epub">2713-265X</issn><publisher><publisher-name>TSU publishing</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.29001/2073-8552-2019-34-1-10-17</article-id><article-id custom-type="elpub" pub-id-type="custom">cardiotomsk-671</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ И ЛЕКЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS AND LECTURES</subject></subj-group></article-categories><title-group><article-title>ВОЗМОЖНОСТИ И ОГРАНИЧЕНИЯ СПЕКЛ-ТРЕКИНГ СТРЕСС-ЭХОКАРДИОГРАФИИ</article-title><trans-title-group xml:lang="en"><trans-title>CAPABILITIES AND LIMITATIONS OF SPECKLE TRACKING STRESS ECHOCARDIOGRAPHY</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Степанова</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Stepanova</surname><given-names>A. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>клинический аспирант кафедры кардиологии, терапии и функциональной диагностики с курсом нефрологии,</p><p>121359, Москва, ул. Маршала Тимошенко, 19, стр. 1а</p></bio><bio xml:lang="en"><p>Postgraduate Student of the Department of Cardiology, Therapy and Functional Diagnostics with Nephrology Course,</p><p>19, bldg. 1A, Marshal Timoshenko str., Moscow, 121359</p></bio><email xlink:type="simple">fr.anya.dz@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алехин</surname><given-names>М. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Alekhin</surname><given-names>M. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук, профессор кафедры кардиологии, терапии и функциональной диагностики с курсом нефрологии, 121359, Москва, ул. Маршала Тимошенко, 19, стр. 1а;</p><p>заведующий отделением функциональной диагностики, 121359, Москва, ул. Маршала Тимошенко, 15</p></bio><bio xml:lang="en"><p>Dr. Sci. (Med.), Professor of the Department of Cardiology, Therapy and Functional Diagnostics with Nephrology Course, 19, bldg. 1A, Marshal Timoshenko str., Moscow, 121359;</p><p>Head of Functional Diagnostics Department, 15, Marshal Timoshenko str., Moscow, 121359</p></bio><email xlink:type="simple">mike.nikolaich@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>«Центральная государственная медицинская академия» Управления делами Президента Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Central State Medical Academy of the Administrative Department of the President of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>«Центральная государственная медицинская академия» Управления делами Президента Российской Федерации;&#13;
«Центральная клиническая больница с поликлиникой» Управления делами Президента Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Central State Medical Academy of the Administrative Department of the President of the Russian Federation;&#13;
Central Clinical Hospital of the Presidential Administration of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>19</day><month>04</month><year>2019</year></pub-date><volume>34</volume><issue>1</issue><fpage>10</fpage><lpage>17</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Степанова А.И., Алехин М.Н., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Степанова А.И., Алехин М.Н.</copyright-holder><copyright-holder xml:lang="en">Stepanova A.I., Alekhin M.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.sibjcem.ru/jour/article/view/671">https://www.sibjcem.ru/jour/article/view/671</self-uri><abstract><p>Стресс-эхокардиография является методикой, которая позволяет оценивать сократимость миокарда и внутрисердечную гемодинамику в условиях физической нагрузки или реакции на фармакологический препарат. Оценка систолической функции левого желудочка (ЛЖ) играет важную роль в установлении прогноза и выборе стратегии лечения при различных сердечно-сосудистых заболеваниях. Технология спекл-трекинг — одна из наиболее перспективных для определения значений деформации ЛЖ, благодаря которой возможна не только визуальная, но и количественная оценка сократимости миокарда ЛЖ как в состоянии покоя, так и при проведении нагрузочных тестов. В данном обзоре проанализированы возможности применения спекл-трекинг стресс-эхокардиографии c физической нагрузкой или с введением фармакологического препарата у здоровых лиц и пациентов с различными заболеваниями, такими как ишемическая болезнь сердца (ИБС), клапанные пороки сердца, сахарный диабет, микрососудистое поражение. Наряду с этим рассмотрены различия между значениями продольной систолической деформации ЛЖ в зависимости от возраста, а также проведено сопоставление данных спекл-трекинг стресс-эхокардиографии с результатами коронарной ангиографии и компьютерной томографии коронарных артерий.</p></abstract><trans-abstract xml:lang="en"><p>Stress echocardiography is a technique that allows to evaluate myocardial contractility and intracardiac hemodynamics under conditions of physical exercise or reaction to a pharmacological drug. Evaluation of systolic function of the left ventricle plays an important role in establishing the prognosis and choosing a treatment strategy for various cardiovascular diseases. Speckle tracking technique is one of the most promising methods for determining values of left ventricular deformation, due to which not only visual, but also quantitative assessment of left ventricular myocardial contractility is possible at rest and during stress tests. In this review, we analyzed the possibility of using speckle tracking stress echocardiography with physical exercise or with the pharmacological drug, in order to diagnose various diseases, such as ischemic heart disease, valvular heart disease, diabetes mellitus, and microvascular damage. Along with this, differences between the values of the longitudinal systolic deformation depending on age were considered. We also compared diagnostic values of the data of speckle-tracking stress echocardiography and coronary angiography and values of the data of speckle-tracking stress echocardiography and computed tomography of the coronary arteries.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>стресс-эхокардиография</kwd><kwd>спекл-трекинг</kwd><kwd>продольная систолическая деформация</kwd></kwd-group><kwd-group xml:lang="en"><kwd>stress echocardiography</kwd><kwd>speckle tracking</kwd><kwd>longitudinal systolic deformation</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Tops L.F., Delgado V., Marsan N.A., Bax J.J. Myocardial strain to detect subtle left ventricular systolic dysfunction. Eur. J. Heart Fail. 2017 Mar.;19(3):307–313. DOI: 10.1002/ejhf.694.</mixed-citation><mixed-citation xml:lang="en">Tops L.F., Delgado V., Marsan N.A., Bax J.J. 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