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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cardiotomsk</journal-id><journal-title-group><journal-title xml:lang="ru">Сибирский журнал клинической и экспериментальной медицины</journal-title><trans-title-group xml:lang="en"><trans-title>Siberian Journal of Clinical and Experimental Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2713-2927</issn><issn pub-type="epub">2713-265X</issn><publisher><publisher-name>TSU publishing</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.29001/2073-8552-2019-34-4-49-54</article-id><article-id custom-type="elpub" pub-id-type="custom">cardiotomsk-862</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ И ЛЕКЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS AND LECTURES</subject></subj-group></article-categories><title-group><article-title>Роль биомаркеров синдрома обструктивного апноэ сна в оценке сердечно-сосудистого риска</article-title><trans-title-group xml:lang="en"><trans-title>The role of obstructive sleep apnea biomarkers in assessment of cardiovascular risk</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3554-0659</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Евлампиева</surname><given-names>Л. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Evlampieva</surname><given-names>L. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Евлампиева Лариса Геннадьевна - кандидат медицинских наук, младший научный сотрудник, лаборатория инструментальной диагностики научного отдела инструментальных методов исследования.</p><p>625026, Тюмень, ул. Мельникайте, 111</p></bio><bio xml:lang="en"><p>Larisa G. Evlampieva - Cand. Sci. (Med.), Junior Research Scientist, Laboratory of Instrumental Diagnostics, Scientific Division of Instrumental Research Methods.</p><p>111, Melnikaite str., Tyumen, 625026</p></bio><email xlink:type="simple">evlampieva.l.g@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1436-8853</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ярославская</surname><given-names>Е. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Yaroslavskaya</surname><given-names>E. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ярославская Елена Ильинична - доктор медицинских наук, исполняющая обязанности заведующего научным отделом инструментальных методов исследования.</p><p>625026, Тюмень, ул. Мельникайте, 111</p></bio><bio xml:lang="en"><p>Elena I. Yaroslavskaya - Dr. Sci. (Med.), Acting Director of the Scientific Division of Instrumental Research Methods.</p><p>111, Melnikaite str., Tyumen, 625026</p></bio><email xlink:type="simple">varoslavskavae@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6601-4120</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Аксенова</surname><given-names>К. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Aksenova</surname><given-names>K. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Аксенова Кристина Васильевна - врач-кардиолог.</p><p>625026, Тюмень, ул. Мельникайте, 111</p></bio><bio xml:lang="en"><p>Kristina V. Aksenova – Cardiologist.</p><p>111, Melnikaite str., Tyumen, 625026</p></bio><email xlink:type="simple">K-medicus@vandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8979-0827</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сергейчик</surname><given-names>О. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Sergeichik</surname><given-names>O. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сергейчик Оксана Ивановна - научный сотрудник, лаборатория инструментальной диагностики научного отдела инструментальных методов исследования.</p><p>625026, Тюмень, ул. Мельникайте, 111</p></bio><bio xml:lang="en"><p>Oksana I. Sergeichik - Research Scientist, Laboratorv of Instrumental Diagnostics, Scientific Division of Instrumental Research Methods.</p><p>111, Melnikaite str., Tyumen, 625026</p></bio><email xlink:type="simple">oisserg1@vandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Тюменский кардиологический научный центр, Томский национальный исследовательский медицинский центр, Российская академия наук</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Tyumen Cardiology Research Center, Tomsk National Research Medical Center, Russian Academy of Sciences</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>24</day><month>01</month><year>2020</year></pub-date><volume>34</volume><issue>4</issue><fpage>49</fpage><lpage>54</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Евлампиева Л.Г., Ярославская Е.И., Аксенова К.В., Сергейчик О.И., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Евлампиева Л.Г., Ярославская Е.И., Аксенова К.В., Сергейчик О.И.</copyright-holder><copyright-holder xml:lang="en">Evlampieva L.G., Yaroslavskaya E.I., Aksenova K.V., Sergeichik O.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.sibjcem.ru/jour/article/view/862">https://www.sibjcem.ru/jour/article/view/862</self-uri><abstract><p>Обзор содержит современные представления о биомаркерах синдрома обструктивного апноэ сна (СОАС) и об их месте в оценке сердечно-сосудистого риска. Причинно-следственные взаимосвязи между ССЗ и СОАС все еще изучены недостаточно. Нуждается в оценке независимое влияние СОАС на сердечно-сосудистый риск в различных субгруппах пациентов. При этом следует учитывать, что в диагностике и оценке эффективности лечения СОАС можно опираться не только на специфические маркеры, но и на простые доступные методы лабораторного исследования.</p></abstract><trans-abstract xml:lang="en"><p>The review article presents a contemporary view on biomarkers of obstructive sleep apnea syndrome (OSAS) and their role in the assessment of cardiovascular risk. The cause-effect relationships between cardiovascular diseases and OSAS are still poorly understood. The assessment of an independent impact of OSAS on the cardiovascular risk in various subgroups of patients is required. It should be taken into account that one may rely not only on specific markers, but also on available routine laboratory tests in order to diagnose OSAS and evaluate the effectiveness of its treatment.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>синдром обструктивного апноэ сна</kwd><kwd>сердечно-сосудистый риск</kwd><kwd>СРАР-терапия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>obstructive sleep apnea</kwd><kwd>cardiovascular risk</kwd><kwd>CPAP-therapy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Шамшева Д.С. Синдром обструктивного апноэ: современное состояние проблемы. Лечебное дело. 2014;1:14-16.</mixed-citation><mixed-citation xml:lang="en">Shamsheva D.S. Obstructive sleep apnea: modern state of the problem. J. 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