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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cardiotomsk</journal-id><journal-title-group><journal-title xml:lang="ru">Сибирский журнал клинической и экспериментальной медицины</journal-title><trans-title-group xml:lang="en"><trans-title>Siberian Journal of Clinical and Experimental Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2713-2927</issn><issn pub-type="epub">2713-265X</issn><publisher><publisher-name>TSU publishing</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.29001/2073-8552-2020-35-1-142-150</article-id><article-id custom-type="elpub" pub-id-type="custom">cardiotomsk-925</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЭКСПЕРИМЕНТАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>EXPERIMENTAL STUDIES</subject></subj-group></article-categories><title-group><article-title>Полиморфизм генов фолатного цикла у больных подагрой в популяции русских Забайкальского края</article-title><trans-title-group xml:lang="en"><trans-title>Polymorphism in folate cycle genes in patients with gout in the Russian population of Trans-Baikal Territory</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0350-0698</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кушнаренко</surname><given-names>Н. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Kushnarenko</surname><given-names>N. N.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"><p>39A, Gorky str., Chita, 672090, Russian Federation </p></bio><email xlink:type="simple">natalia.kushnarenko1@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3243-2951</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мишко</surname><given-names>М. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Mishko</surname><given-names>M. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"><p>Assistant Professor, Department of Internal Medicine, Pediatric and Dental Faculties</p><p>39A, Gorky str., Chita, 672090, Russian Federation </p></bio><email xlink:type="simple">mm_you@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8410-5827</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Медведев</surname><given-names>Т. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Medvedeva</surname><given-names>T. A.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"><p>Assistant Professor, Department of Internal Medicine, Pediatric and Dental Faculties </p><p>39A, Gorky str., Chita, 672090, Russian Federation </p></bio><email xlink:type="simple">saidi-tma@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Читинская государственная медицинская академия Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Chita State Medical Academy</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>12</day><month>04</month><year>2020</year></pub-date><volume>35</volume><issue>1</issue><fpage>142</fpage><lpage>150</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Кушнаренко Н.Н., Мишко М.Ю., Медведев Т.А., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Кушнаренко Н.Н., Мишко М.Ю., Медведев Т.А.</copyright-holder><copyright-holder xml:lang="en">Kushnarenko N.N., Mishko M.Y., Medvedeva T.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.sibjcem.ru/jour/article/view/925">https://www.sibjcem.ru/jour/article/view/925</self-uri><abstract/><trans-abstract xml:lang="en"/><kwd-group xml:lang="ru"><kwd>подагра</kwd><kwd>мочевая кислота</kwd><kwd>генетический полиморфизм</kwd><kwd>фолатный цикл</kwd><kwd>MTHFR</kwd><kwd>MTR</kwd><kwd>MTRR</kwd></kwd-group><kwd-group xml:lang="en"><kwd>gout</kwd><kwd>uric acid</kwd><kwd>genetic polymorphism</kwd><kwd>folate cycle</kwd><kwd>MTHFR</kwd><kwd>MTR</kwd><kwd>MTRR</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Гринштейн Ю.И., Шабалин В.В., Руф Р.Р., Петрова М.М., Артюхов И.П., Шальнова С. 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