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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cardiotomsk</journal-id><journal-title-group><journal-title xml:lang="ru">Сибирский журнал клинической и экспериментальной медицины</journal-title><trans-title-group xml:lang="en"><trans-title>Siberian Journal of Clinical and Experimental Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2713-2927</issn><issn pub-type="epub">2713-265X</issn><publisher><publisher-name>TSU publishing</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.29001/2073-8552-2014-29-3-37-40</article-id><article-id custom-type="elpub" pub-id-type="custom">cardiotomsk-97</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL STUDIES</subject></subj-group></article-categories><title-group><article-title>Элементы системного воспалительного ответа и клинические параллели у пациентов с декомпенсированной хронической сердечной недостаточностью</article-title><trans-title-group xml:lang="en"><trans-title>Elements of systemic inflammatory response and clinical implications in patients with decompensated chronic heart failure</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Костенко</surname><given-names>Виктор Авенирович</given-names></name><name name-style="western" xml:lang="en"><surname>Kostenko</surname><given-names>V. A.</given-names></name></name-alternatives><email xlink:type="simple">vic2012tor@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Арискина</surname><given-names>Ольга Борисовна</given-names></name><name name-style="western" xml:lang="en"><surname>Ariskina</surname><given-names>O. B.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Осипова</surname><given-names>Ирина Викторовна</given-names></name><name name-style="western" xml:lang="en"><surname>Osipova</surname><given-names>I. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пивоварова</surname><given-names>Людмила Павловна</given-names></name><name name-style="western" xml:lang="en"><surname>Pivovarova</surname><given-names>L. P.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Скородумова</surname><given-names>Елена Андреевна</given-names></name><name name-style="western" xml:lang="en"><surname>Skorodumova</surname><given-names>E. A.</given-names></name></name-alternatives><email xlink:type="simple">elskor@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сорока</surname><given-names>Владимир Васильевич</given-names></name><name name-style="western" xml:lang="en"><surname>Soroka</surname><given-names>V. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Федоров</surname><given-names>Артем Николаевич</given-names></name><name name-style="western" xml:lang="en"><surname>Fedorov</surname><given-names>A. N.</given-names></name></name-alternatives><email xlink:type="simple">artem_fedorov@inbox.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кисельгоф</surname><given-names>Олег Геннадьевич</given-names></name><name name-style="western" xml:lang="en"><surname>Kiselgof</surname><given-names>O. G.</given-names></name></name-alternatives><email xlink:type="simple">kiselgof@emergency.spb.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБУ "Санкт-Петербургский научно-исследовательский институт скорой помощи им. И.И. Джанелидзе"</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Institute for Emergency Medical Care n.a. I.I. Dzhanelidze</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>06</day><month>09</month><year>2016</year></pub-date><volume>29</volume><issue>3</issue><fpage>37</fpage><lpage>40</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Костенко В.А., Арискина О.Б., Осипова И.В., Пивоварова Л.П., Скородумова Е.А., Сорока В.В., Федоров А.Н., Кисельгоф О.Г., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Костенко В.А., Арискина О.Б., Осипова И.В., Пивоварова Л.П., Скородумова Е.А., Сорока В.В., Федоров А.Н., Кисельгоф О.Г.</copyright-holder><copyright-holder xml:lang="en">Kostenko V.A., Ariskina O.B., Osipova I.V., Pivovarova L.P., Skorodumova E.A., Soroka V.V., Fedorov A.N., Kiselgof O.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.sibjcem.ru/jour/article/view/97">https://www.sibjcem.ru/jour/article/view/97</self-uri><abstract><p>Представлены результаты обследования и лечения 105 пациентов с декомпенсированной хронической сердечной недостаточностью (ХСН). Исследовались иммунный статус и клиническое течение заболевания у больных, госпитализированных в 2010-2013 гг. в Санкт-Петербургский научно-исследовательский институт скорой помощи им. И.И. Джанелидзе (СПб НИИСП им. И.И. Джанелидзе). Показана активация системного воспаления у этой категории пациентов и ее негативное влияние на клиническое течение и прогноз заболевания.</p></abstract><trans-abstract xml:lang="en"><p>The article presents the results of examination and treatment of 105 patients with decompensated chronic heart failure. Immune status and clinical course of disease were studied in patients hospitalized to the SPb RIEMC in 2010-2013. Activation of systemic inflammation and its negative impact on the course and prognosis of disease are demonstrated.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>декомпенсированная сердечная недостаточность</kwd><kwd>системное воспаление</kwd><kwd>иммунный статус</kwd><kwd>decompensated heart failure</kwd><kwd>systemic inflammation</kwd><kwd>immune status</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Болезни сердца и сосудов. Руководство Европейского общества кардиологов / под ред. А.Д. Кэмма, Т.Ф. Люшера, П.В. Серруиса. - М.: ГЭОТАР-Медиа, 2011. - 1437 с.</mixed-citation><mixed-citation xml:lang="en">Болезни сердца и сосудов. Руководство Европейского общества кардиологов / под ред. А.Д. Кэмма, Т.Ф. Люшера, П.В. 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