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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cardiotomsk</journal-id><journal-title-group><journal-title xml:lang="ru">Сибирский журнал клинической и экспериментальной медицины</journal-title><trans-title-group xml:lang="en"><trans-title>Siberian Journal of Clinical and Experimental Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2713-2927</issn><issn pub-type="epub">2713-265X</issn><publisher><publisher-name>TSU publishing</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.29001/2073-8552-2020-35-2-26-34</article-id><article-id custom-type="elpub" pub-id-type="custom">cardiotomsk-971</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ И ЛЕКЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS AND LECTURES</subject></subj-group></article-categories><title-group><article-title>Сердечно-сосудистые заболевания и хроническая обструктивная болезнь легких: этиопатогенетическая взаимосвязь и клиническое значение (обзор литературы)</article-title><trans-title-group xml:lang="en"><trans-title>Cardiovascular diseases and chronic obstructive pulmonary disease: etiopathogenetic relationship and clinical signifi cance (literature review)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2712-0227</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чаулин</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Chaulin</surname><given-names>A. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач, 443070, Самара, ул. Аэродромная, 43;</p><p>ассистент кафедры, 443099, Самара, ул. Чапаевская, 89</p></bio><bio xml:lang="en"><p>Medical Doctor, Pathologist, 43, Aerodromnaya str., Samara, 443070;</p><p>Lecturer Assistant, 89, Chapayevskaya str., Samara, 443099</p></bio><email xlink:type="simple">alekseymichailovich22976@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6453-2976</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дупляков</surname><given-names>Д. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Duplyakov</surname><given-names>D. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук, заместитель главного врача по медицинской части, 443070, Самара, ул. Аэродромная, 43;</p><p>профессор кафедры, 443099, Самара, ул. Чапаевская, 89</p></bio><bio xml:lang="en"><p>Dr. Sci. (Med.), Director Deputy for Medical Issues, 43, Aerodromnaya str., Samara, 443070;</p><p>Professor, 89, Chapayevskaya str., Samara, 443099</p></bio><email xlink:type="simple">duplyakov@yahoo.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Самарский областной клинический кардиологический диспансер;&#13;
Самарский государственный медицинский университет Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Samara Regional Cardiology Dispensary;&#13;
Samara State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>04</day><month>07</month><year>2020</year></pub-date><volume>35</volume><issue>2</issue><fpage>26</fpage><lpage>34</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Чаулин А.М., Дупляков Д.В., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Чаулин А.М., Дупляков Д.В.</copyright-holder><copyright-holder xml:lang="en">Chaulin A.M., Duplyakov D.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.sibjcem.ru/jour/article/view/971">https://www.sibjcem.ru/jour/article/view/971</self-uri><abstract><p>Сердечно-сосудистые заболевания (ССЗ) и хроническая обструктивная болезнь легких (ХОБЛ) часто сосуществуют. Коморбидность ССЗ и ХОБЛ является серьезной современной медико-социальной проблемой. В этой статье рассматриваются основные факторы риска, которые являются общими для ХОБЛ и ССЗ: курение, воспаление, малоподвижный образ жизни, старение, окислительный стресс. Также обсуждаются патогенетические механизмы, лежащие в основе связи между ХОБЛ и ССЗ.</p></abstract><trans-abstract xml:lang="en"><p>Cardiovascular diseases (CVD) and chronic obstructive pulmonary disease (COPD) often coexist. Comorbidity of CVD and COPD is a serious modern medical and social problem. This article discusses the main risk factors that are common for COPD and CVD: smoking, infl ammation, a sedentary lifestyle, aging, and oxidative stress. Pathogenetic mechanisms underlying the relationship between COPD and CVD are also discussed.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>коморбидность</kwd><kwd>полиморбидность</kwd><kwd>факторы риска</kwd><kwd>патофизиология</kwd><kwd>сердечно-сосудистые заболевания</kwd><kwd>хроническая обструктивная болезнь легких</kwd></kwd-group><kwd-group xml:lang="en"><kwd>comorbidity</kwd><kwd>polymorbidity</kwd><kwd>risk factors</kwd><kwd>pathophysiology</kwd><kwd>cardiovascular disease</kwd><kwd>chronic obstructive pulmonary disease</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Feinstein A.R. The pre-therapeutic classification of comorbidity in chronic disease. J. Chronic. Dis. 1970;23(7):455–468. DOI: 10.1016/0021-9681(70)90054-8.</mixed-citation><mixed-citation xml:lang="en">Feinstein A.R. The pre-therapeutic classifi cation of comorbidity in chronic disease. J. 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