Composition and metabolic activity of the gut microbiota in obese children and adolescents
Ju. G. Samoilova,
O. A. Oleynik,
E. V. Sagan,
I. N. Vorozhtsova,
T. A. Filippova,
N. S. Denisov,
D. A. Dyakov https://doi.org/10.29001/2073-8552-2020-35-3-38-46
Abstract
This review summarizes the results from national and international studies regarding the quantitative and qualitative composition of intestinal microbiota in health and the dominance of certain bacteria in the intestinal microbiota of obese children. Moreover, we discuss the relationships between the development of obesity and the changes in the composition and metabolic activity of intestinal microbiota in children. These analyses are of scientific interest from the perspective of finding new targets and approaches to conservative management aimed at preventing and treating obesity through the restoration of intestinal microflora.
About the Authors
Ju. G. Samoilova
Siberian State Medical University
Russian Federation
Russian Federation
Julia G. Samoilova Dr. Sci. (Med.), Professor, Department of Endocrinology and Diabetology, Head of the Department of Children’s Diseases, Head of Clinical Research Center, Siberian State Medical University; Leading Specialist for Prevention, Department of Healthcare of the Tomsk Region Administration
2, Moscovsky tract, Tomsk, 634050, Russian Federation
O. A. Oleynik
Siberian State Medical University
Russian Federation
Russian Federation
Oxana A. Oleynik, Cand. Sci. (Med.), Associate Professor, Department of Endocrinology and Diabetology
2, Moscovsky tract, Tomsk, 634050, Russian Federation
E. V. Sagan
Siberian State Medical University
Russian Federation
Russian Federation
Elena V. Sagan, Assistant Professor, Department of Children’s Diseases
2, Moscovsky tract, Tomsk, 634050, Russian Federation
I. N. Vorozhtsova
Siberian State Medical University
Russian Federation
Russian Federation
Irina N. Vorozhtsova, Dr. Sci. (Med.), Professor, Head of the Department of Endocrinology and Diabetology
2, Moscovsky tract, Tomsk, 634050, Russian Federation
T. A. Filippova
Siberian State Medical University
Russian Federation
Russian Federation
Irina N. Vorozhtsova, Dr. Sci. (Med.), Professor, Head of the Department of Endocrinology and Diabetology
2, Moscovsky tract, Tomsk, 634050, Russian Federation
N. S. Denisov
Siberian State Medical University
Russian Federation
Russian Federation
Nikita S. Denisov, Medical Student
2, Moscovsky tract, Tomsk, 634050, Russian Federation
D. A. Dyakov
Siberian State Medical University
Russian Federation
Russian Federation
Denis A. Dyakov, Assistant Professor, Department of General Biochemistry and Molecular Biology with Course of Clinical Laboratory Diagnostics
2, Moscovsky tract, Tomsk, 634050, Russian Federation
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Review
For citations:
Samoilova J.G., Oleynik O.A., Sagan E.V., Vorozhtsova I.N., Filippova T.A., Denisov N.S., Dyakov D.A. Composition and metabolic activity of the gut microbiota in obese children and adolescents. Siberian Journal of Clinical and Experimental Medicine. 2020;35(3):38-46. (In Russ.) https://doi.org/10.29001/2073-8552-2020-35-3-38-46
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