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Immediate results of off-pump versus on-pump coronary artery bypass grafting using autoarterial conduits in situ and Y-graft configurations

https://doi.org/10.29001/2073-8552-2021-36-4-87-95

Abstract

Aim. To compare the immediate results of off-pump versus on-pump coronary artery bypass grafting (CABG) using autoarterial conduits.

Material and Methods. From January 2018 to September 2021, 178 coronary artery bypass grafting operations using autoarterial conduits were performed in the Department No. 1 of the Federal Center for Cardiovascular Surgery (Krasnoyarsk). The operation was performed on a beating heart in 88 patients (group 1) and using cardiopulmonary bypass in 90 patients (group 2). The majority of patients were males in both groups: 76 (86.3%) and 75 (83.3%) patients (p = 0.287). The patients were comparable in age (61.6 ± 7.7 and 60.2 ± 7.5 years, p = 0.237), body mass index (30.9 ± 5.7 and 29.8 ± 5, p = 0.18), and the presence of concomitant diabetes mellitus (30 (34%) and 19 (21.1%), p = 0.052). There were significantly more patients with hemodynamically significant lesions of the brachiocephalic arteries in group 1 (27 (30.7%) versus 13 (14.4%), p = 0.009) and calcification of the ascending aorta (24 (27.3%) versus 11 (12.2%), p = 0.011). The number of hemodynamically significant affected coronary arteries did not differ between the groups: 2.6 ± 0.7 versus 2.5 ± 0.5 (p = 0.393).

Results. Both internal thoracic arteries were used in situ or in the form of Y-grafts in both groups depending on the number of distal anastomoses. Hospital mortality was 2 patients (2.2%), both from group 2 (p = 0.161). The groups were comparable in the number of distal anastomoses (2.7 ± 0.7 and 2.7 ± 0.6, p = 0.532), the incidence of acute perioperative myocardial infarction (1 (1.1%) and 1 (1.1%), p = 0.987), neurological complications (1 (1.1%) and 2 (2.2%), p = 0.576), and bleeding requiring resternotomy (1 (1.1%) and 3 (3.3%), p = 0.325). Deep sternal wood infection was absent in both groups.

Conclusion. Autoarterial coronary artery bypass grafting is an effective method of myocardial revascularization in both the beating heart surgery and in cardiopulmonary bypass conditions. This method should be considered an operation of choice for patients with multiple coronary artery disease. The performance of operations in the conditions of cardiopulmonary bypass does not affect the increase in the number of cardiocerebral events in the postoperative period. 

About the Authors

A. G. Muradov
Federal Center for Cardiovascular Surgery
Russian Federation

Cardiovascular Surgeon, Cardiovascular Department No. 1,

45, Karaulnaya str., Krasnoyarsk, 660020



V. U. Efendiev
Federal Center for Cardiovascular Surgery
Russian Federation

Cand. Sci. (Med.), Cardiovascular Surgeon, Cardiovascular Department No. 1,

45, Karaulnaya str., Krasnoyarsk, 660020



A. V. Andin
Federal Center for Cardiovascular Surgery
Russian Federation

Cand. Sci. (Med.), Cardiovascular Surgeon, Head of Cardiovascular Department No. 1,

45, Karaulnaya str., Krasnoyarsk, 660020



D. B. Drobot
Krasnoyarsk State Medical University named after Professor V.F. Voyno-Yasenetsky; Federal Center for Cardiovascular Surgery
Russian Federation

Dr. Sci. (Med.), Professor, Department and Clinic of Cardiovascular Surgery, Institute of Postgraduate Education, 1, Partizana Zheleznyaka str., Krasnoyarsk, 660022;

45, Karaulnaya str., Krasnoyarsk, 660020



V. A. Sakovich
Federal Center for Cardiovascular Surgery; Krasnoyarsk State Medical University named after Professor V.F. Voyno-Yasenetsky
Russian Federation

Dr. Sci. (Med.), Professor, Chief Physician, 45, Karaulnaya str., Krasnoyarsk, 660020;

Head of the Department and Clinic of Cardiovascular Surgery, 1, Partizana Zheleznyaka str., Krasnoyarsk, 660022



References

1. Gmurov D.V., Parfenteva M.A., Semenova Y.V. Coronary heart disease. Colloquium Journal. 2020;29(81):32–37 (In Russ.). DOI: 10.24412/2520-2480-2020-2981-32-37.

2. Neumann F.J., Sousa-Uva M., Ahlsson A., Alfonso F., Banning A.P., Benedetto U. et al. ESC/EACTS Guidelines on myocardial revascularization. Eur. Heart J. 2019;40(2):87–165. DOI:10.1093/eurheartj/ehy394.

3. Hua M., Scales D.C., Cooper Z., Pinto R., Moitra V., Wunsch H. Impact of public reporting of 30-day mortality on timing of death after coronary artery bypass graft surgery. Anesthesiology. 2017;127(6):953–960. DOI: 10.1097/ALN.0000000000001884.

4. Lamy A., Devereaux P.J., Prabhakaran D., Taggart D.P., Hu S., Straka Z. et al. Five-year outcomes after off-pump or on-pump coronary-artery bypass grafting. N. Engl. J. Med. 2016;375(24):2359–2368. DOI: 10.1056/NEJMoa1601564.

5. Hueb W.,Rezende P.C., Gersh B.J.,Soares P.R., Favarato D., Lima E.G. et al. Ten-year follow-up of off-pump and on-pump multivessel coronary artery bypass grafting: MASS III. Angiology. 2019;70(4):337–344. DOI: 10.1177/0003319718804402.

6. Diegeler A., Borgermann J., Kappert U., Breuer M., Böning A., Ursulescu A. et al. Off-pump versus on-pump coronary artery bypass grafting in elderly patients. N. Engl. J. Med. 2013;368(13):1189–1198. DOI: 10.1056/NEJMoa1211666.

7. Niclauss L. Techniques and standards in intraoperative graft verification by transit time flow measurement after coronary artery bypass graft surgery: A critical review. Eur. J. Cardiothorac. Surg. 2016;51(1):26–33. DOI: 10.1093/ejcts/ezw203.

8. Patel V., Unai S., Gaudino M., Bakaeen F. Current readings on outcomes after off-pump coronary artery bypass grafting. Semin. Thorac. Cardiovasc. Surg. 2019;31(4):726–733. DOI: 10.1053/j.semtcvs.2019.05.012.

9. Diegeler A., Börgermann J., Kappert U., Hilker M., Doenst T., Böning A. et al. Five-year outcome after off-pump or on-pump coronary artery bypass grafting in elderly patients. Circulation. 2019;139(16):1865–1871. DOI: 10.1161/CIRCULATIONAHA.118.035857.

10. Gaudino M., Benedetto U., Bakaeen F., Rahouma M., Tam D.Y., Abouarab A. et al. Off- versus on-pump coronary surgery and the effect of follow-up length and surgeons’ experience: А meta-analysis. J. Am. Heart Assoc.2018;7(21):e010034. DOI: 10.1161/JAHA.118.010034.

11. Marui A., Okabayashi H., Komiya T., Tanaka S., Furukawa Y., Kita T. et al. Benefits of off-pump coronary artery bypass grafting in high-risk patients. Circulation. 2012;126(11):S151–157. DOI: 10.1161/CIRCULATIONAHA.111.083873.

12. Puskas J.D., Kilgo P.D., Lattouf O.M., Thourani V.H., Cooper W.A., Vassiliades T.A. et al. Off-pump coronary bypass provides reduced mortality and morbidity and equivalent 10-year survival. Ann. Thorac. Surg. 2008;86(4):1139–1146. DOI: 10.1016/j.athoracsur.2008.05.073.

13. Luo T., Ni Y. Short-term and long-term postoperative safety of offpump versus on-pump coronary artery bypass grafting for coronary heart disease: A meta-analysis for randomized сontrolled trials. Thorac. Cardiovasc. Surg. 2015;63(4):319–327. DOI:10.1055/s-0035-1544232.

14. Shroyer A.L., Hattler B., Wagner T.H., Collins J.F., Baltz J.H., Quin J.A. et al. Five-year outcomes after on-pump and off-pump coronary-artery bypass. N. Engl. J. Med. 2017;377(7):623–632. DOI: 10.1056/NEJMoa1614341.

15. Houlind K., Kjeldsen B.J., Madsen S.N., Rasmussen B.S., Holme S.J., Nielsen P.H. et al. On-pump versus off-pump coronary artery bypass surgery in elderly patients: Results from the Danish on-pump versus off-pump randomization study. Circulation. 2012;125:2431–2439. DOI: 10.1161/CIRCULATIONAHA.111.052571.

16. Benedetto U., Altman D.G., Gerry S., Gray A., Lees B., Pawlaczyk R. et al. Arterial Revascularization Trial Investigators. Pedicled and skeletonized single and bilateral internal thoracic artery grafts and the incidence of sternal wound complications: insights from the Arterial Revascularization Trial. J. Thorac. Cardiovasc. Surg. 2016;152:270–276. DOI: 10.1016/j.jtcvs.2016.03.056.


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For citations:


Muradov A.G., Efendiev V.U., Andin A.V., Drobot D.B., Sakovich V.A. Immediate results of off-pump versus on-pump coronary artery bypass grafting using autoarterial conduits in situ and Y-graft configurations. Siberian Journal of Clinical and Experimental Medicine. 2022;37(1):87-95. (In Russ.) https://doi.org/10.29001/2073-8552-2021-36-4-87-95

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ISSN 2713-2927 (Print)
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