The role of therapeutic hypothermia in reducing of the reperfusion injury in patients with STEMI: narrative review

Despite timely coronary reperfusion, about 7% of patients with acute myocardial infarction die during hospitalization and around 23% survivors develop heart failure within one year. Reperfusion injury is largely responsible for the final infarct size. Although, there is some progress in myocardial revascularization, prevention and treatment of the reperfusion injury in myocardial infarction patients is not successful enough in clinical practice. Hypothermia can reduce reperfusion injury and improve survival and reduce the number of complications in patients with myocardial infarction.

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