THE INTRACARDIAC HEMODYNAMICS IN CHILDREN WITH SINGLE VENTRICLE PATHOLOGY SIX MONTHS AFTER TOTAL CAVOPULMONARY CONNECTION PROCEDURE

Complex anatomy, diversity of anatomic variants, prevalence of right or left part of the heart, and the particular movements of the single ventricle complicate echocardiographic assessment of ventricular function in children with single ventricle pathology. The purpose of the present investigation was to evaluate the status of intracardiac hemodynamics in children with single ventricle pathology after a total cavopulmonary connection procedure. Methods: A comparative analysis of two groups was performed. The main group included 39 patients with single ventricle pathology six month after a total cavopulmonary connection procedure. The control group included 349 healthy children without cardiovascular system pathology. Age and weight did not differ between two groups. Results: When comparing two groups, a statistically significant correlation was observed in such echocardiographic values as the sphericity index (p<0.001), ejection fraction (EF) (p<0.001), and Tei index (p<0.001). The study showed that normative values of end diastolic volume of the left ventricle were higher in children with single ventricle pathology compared with those in healthy children. Conclusions. Among the indices evaluating myocardial contractility, max dp/dt appears to be the best index in children with single ventricle pathology. The increasing of the common atrium size (dilatation) can lead to single ventricle dysfunction (significant reduction of contractility).

врожденный порок сердца, эхокардиография, единственный желудочек сердца, тотальное кавопульмональное соединение, congenital heart disease, echocardiography, single ventricle pathology, total cavopulmonary connection procedure

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