The role of L-arginine as a donor of nitric oxide and the prospects for its use: the review
https://doi.org/10.29001/2073-8552-2024-39-3-34-40
Abstract
The article discusses recent research on the effective and safe use of the amino acid L-arginine for medicinal purposes in various pathologies. The practical significance of using L-arginine as a source of nitric oxide is considered. The physiological role of nitric oxide, the main vasodilator, was shown, and its deficiency was found to be a key link in endothelial dysfunction. An analysis of modern studies confirming the effectiveness of L-arginine as a donor of nitric oxide was carried out. Ample evidence suggests that oral administration of L-arginine, within physiological limits, can benefit human health by increasing NO synthesis and hence tissue blood flow.
About the Authors
O. I. Margieva
Institute of Biomedical Investigations – the Affiliate of Vladikavkaz Scientific Centre of the Russian Academy of Sciences, Institute of Biomedical Investigations the Affilliate of Vladikavkaz Scientific Centre of the Russian Academy of Sciences
Russian Federation
Russian Federation
Olga I. Margieva, Junior Research Scientist, Laboratory of Pathobiochemistry
47, Pushkinskaya str., Vladikavkaz, 362025
M. T. Margieva
North Ossetian State Medical Academy of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Milana T. Margieva, Student
40, Pushkinskaya str., Vladikavkaz, 362025
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Review
For citations:
Margieva O.I., Margieva M.T. The role of L-arginine as a donor of nitric oxide and the prospects for its use: the review. Siberian Journal of Clinical and Experimental Medicine. 2024;39(3):34-40. (In Russ.) https://doi.org/10.29001/2073-8552-2024-39-3-34-40
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