Reaction of young physically active men with early repolarization phenomena on a cycle of inhalations of a hypoxic gas mixture
https://doi.org/10.29001/2073-8552-2024-39-3-58-63
Abstract
Aim: To examine a reaction of young physically active men with early repolarization phenomena (ERP) on an inhalation of a hypoxic gas mixture (IHGM).
Material and Methods.17 men (6 with ERP & 11 without it) participated in our study. ECG, echocardiography, clinical blood test and erythropoietin blood test were carried out to every of them initially and on the 1-st and 10-th days after the IHGM.
Results. It was found that end systolic volume was 13,8% more (р = 0,01) and ejection fraction was 8% less (р = 0,01) in ERP group than in non ERP group. These indicators were not change after IHGM. In ERP group on 1-st day after IHGM erythropoietin concentration was 79% more (р = 0,027) and on a 10-th day was 64% more (р = 0,003) than in non-ERP group. In ERP group high fluorescent reticulocyte count on a 1-st day after IHGM was 69% more (р = 0,03) and middle fluorescent reticulocyte count on a 10-th day after IHGM was 13% more (р = 0,04) than in non-ERP group. On a 10-th day after IHGM hematocrit and hemoglobin concentration were 5% (р = 0,01) and 12% (р = 0,01) less than in non ERP group.
Conclusion. Thus, men with ERP have a pronounced reaction of the erythropoiesis system on normobaric hypoxia.
About the Authors
M. V. Kabanov
Federal State Unitary Enterprise “State Science Research Institute of Applied Problems” (FSUE «SSRIAP»)
Russian Federation
Russian Federation
Mikhail V. Kabanov, Senior Research Scientist
27, Bypass Chanel embankment, Saint-Petersburg, 191167
V. N. Nosov
Federal State Unitary Enterprise “State Science Research Institute of Applied Problems” (FSUE «SSRIAP»)
Russian Federation
Russian Federation
Victor N. Nosov, Dr. Sci. (Med.), Chief Research Scientist
27, Bypass Chanel embankment, Saint-Petersburg, 191167
M. M. Galagudza
Federal State Budgetary Institution “Almazov National Medical Research Centre” of the Ministry of Health of the Russian Federation (Almazov National Medical Research Centre)
Russian Federation
Russian Federation
Mikhail M. Galagudza, Dr. Sci. (Med.), Professor, Corresponding Member of RAS, Director of the Institute of Experimental Medicine; Chief Research Scientist, Institute of Microcirculation and Myocardial Metabolism; Head of the Department of Pathology
2, Akkuratova str., Saint-Petersburg, 197341
A. V. Sizov
St. Petersburg State Pediatric Medical University of the Ministry of Health of the Russian Federation (SPSPMU)
Russian Federation
Russian Federation
Alexey V. Sizov, Cand. Sci. (Med.), Associate Professor, Department of Faculty Therapy named after V.A. Waldman
2, Litovskaya str., Saint Petersburg, 194100
E. A. Demchenko
Federal State Budgetary Institution “Almazov National Medical Research Centre” of the Ministry of Health of the Russian Federation (Almazov National Medical Research Centre)
Russian Federation
Russian Federation
Elena A. Demchenko, Dr. Sci. (Med.), Chief Researcher, NIL Rehabilitation, Head of Scientific and Clinical Association of Rehabilitation; Professor, Department of Internal Diseases
2, Akkuratova str., Saint-Petersburg, 197341
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Review
For citations:
Kabanov M.V., Nosov V.N., Galagudza M.M., Sizov A.V., Demchenko E.A. Reaction of young physically active men with early repolarization phenomena on a cycle of inhalations of a hypoxic gas mixture. Siberian Journal of Clinical and Experimental Medicine. 2024;39(3):58-63. (In Russ.) https://doi.org/10.29001/2073-8552-2024-39-3-58-63
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