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Clinical case of toxic epidermal necrolysis (Lyell's syndrome) in pediatric practice

https://doi.org/10.29001/2073-8552-2025-40-2-176-182

Abstract

A clinical case of toxic epidermal necrolysis (TEN) in a pediatric patient is presented as a severe pathological process occurring with widespread skin lesions and erosive lesions of the mucous membranes. TEN develops more often as an allergic reaction in response to drugs, the triggers maybe pathogens of infectious diseases. A drug-induced disease may occur in the practice of a pediatrician. To improve the prognosis, timely diagnosis and the use of an individual treatment protocol are important. The presented clinical case confirms the importance of timely diagnosis and early initiation of individual therapy.

About the Authors

G. D. Alemanova
Orenburg State Medical University
Russian Federation

Galina D. Alemanova, Dr. Sci. (Med.), Professor, Department of Children's Diseases

build. 6, Sovetskaya str., Orenburg city, 460014



L. Yu. Popova
Orenburg State Medical University
Russian Federation

Larisa Yu. Popova, Dr. Sci. (Med.), Professor, Head of the Department of Children's Diseases

build. 6, Sovetskaya str., Orenburg city, 460014



O. V. Kirichenko
Orenburg State Medical University
Russian Federation

Olga V. Kirichenko, Assistant Professor, Department of Children's Diseases

build. 6, Sovetskaya str., Orenburg city, 460014



E. I. Pogrebnova
Regional Children's Clinical Hospital
Russian Federation

Elena I. Pogrebnova, Allergist-immunologist of the highest category

22, str. Garankina str., Orenburg city, 460060



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For citations:


Alemanova G.D., Popova L.Yu., Kirichenko O.V., Pogrebnova E.I. Clinical case of toxic epidermal necrolysis (Lyell's syndrome) in pediatric practice. Siberian Journal of Clinical and Experimental Medicine. 2025;40(2):176-182. (In Russ.) https://doi.org/10.29001/2073-8552-2025-40-2-176-182

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ISSN 2713-2927 (Print)
ISSN 2713-265X (Online)