CLINICAL, EPIDEMIOLOGICAL AND GENETIC CHARACTERISTICS OF ACUTE LEUKEMIAS IN ADULT CLINIC OF NOVOSIBIRSK CITY HEMATOLOGY CENTER
https://doi.org/10.29001/2073-8552-2017-32-2-62-66
Abstract
On the basis of the morbidity rate of various forms of acute leukemia was determined for the 10 year post-hoc analysis in Novosibirsk and Novosibirsk region. immunophenotypic characteristic of acute leukemia of patients living on this territory was made. The structure of genetic and molecular genetic abnormalities occurring in blast cells in case of acute myeloid and lymphoid types of leukemia was surveyed. The Correlation of recurrent variants of acute leukemia in accordance with genetic and biomolecular criteria of The World Health Organization (WНO) classification was determined. The meaning of data of molecular genetic (FISH and mycroarrey genochipping) research studies for scoring perspective of treatment and prognosis of disease was shown.
About the Authors
I. B. Kovynev
Novosibirsk State Medical University
Russian Federation
Russian Federation
T. I. Pospelova
Novosibirsk State Medical University
Russian Federation
Russian Federation
R. V. Tarnovskiy
Novosibirsk State Medical University
Russian Federation
Russian Federation
S. A. Tairova
City Hematology Center of Municipal City Hospital No. 2
Russian Federation
Russian Federation
M. M. Agakishiev
Novosibirsk State Medical University
Russian Federation
Russian Federation
A. V. Mishenin
City Hematology Center of Municipal City Hospital No. 2
Russian Federation
Russian Federation
G. V. Shamaeva
City Hematology Center of Municipal City Hospital No. 2
Russian Federation
Russian Federation
V. S. Ovchinnikov
Novosibirsk State Medical University
Russian Federation
Russian Federation
M. A. Kolesnikova
Novosibirsk State Medical University
Russian Federation
Russian Federation
E. V. Mezit
Novosibirsk State Medical University
Russian Federation
Russian Federation
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Review
For citations:
Kovynev I.B., Pospelova T.I., Tarnovskiy R.V., Tairova S.A., Agakishiev M.M., Mishenin A.V., Shamaeva G.V., Ovchinnikov V.S., Kolesnikova M.A., Mezit E.V. CLINICAL, EPIDEMIOLOGICAL AND GENETIC CHARACTERISTICS OF ACUTE LEUKEMIAS IN ADULT CLINIC OF NOVOSIBIRSK CITY HEMATOLOGY CENTER. Siberian Journal of Clinical and Experimental Medicine. 2017;32(2):62-66. (In Russ.) https://doi.org/10.29001/2073-8552-2017-32-2-62-66
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