FUNCTIONAL RECOVERY OF RADIAL ARTERY CONDUIT FOR CORONARY ARTERY BYPASS GRAFTING
https://doi.org/10.29001/2073-8552-2018-33-3-30-35
Abstract
The authors have studied the effect of lercanidipine on the functional status of radial artery used as conduit for CABG in patients with coronary artery stenosis. Endothelium-dependent vasodilation (ΔD) was evaluated preoperatively by using duplex ultrasound. Patients were divided into groups I and II with ΔD≥8% and ΔD<8%, respectively. Group II was divided into groups IIA (lercanidipine) and IIB (control). Mechanical force of isolated arterial segments was initially lower in group I. Preoperative treatment with lercanidipine (2.5–5 mg/kg for 5–7 days) led to a significant increase in endothelium-dependent vasodilation and decrease in tone of isolated arterial segments. Preoperative treatment with lercanidipine effectively preserved dilatational properties of arterial conduit.
About the Authors
T. M. Ripp
Cardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences
Russian Federation
Russian Federation
Dr. Sci. (Med.), Senior Research Fellow, Department of Arterial Hypertension
111a, Kievskaya str., Tomsk, 634012, Russian Federation
D. S. Kondratieva
Cardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences
Russian Federation
Russian Federation
Cand. Sci. (Med.), Research Fellow, Laboratory of Molecular and Cellular Pathology and Gene Diagnostics
111a, Kievskaya str., Tomsk, 634012, Russian Federation
S. A. Afanasiev
Cardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences
Russian Federation
Russian Federation
Dr. Sci. (Med.), Professor, Head of the Laboratory of Molecular and Cellular Pathology and Gene Diagnostics
111a, Kievskaya str., Tomsk, 634012, Russian Federation
E. F. Muslimova
Cardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences
Russian Federation
Russian Federation
Cand. Sci. (Med.), Research Fellow, Laboratory of Molecular and Cellular Pathology and Gene Diagnostics
111a, Kievskaya str., Tomsk, 634012, Russian Federation
B. N. Kozlov
Cardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences
Russian Federation
Russian Federation
Dr. Sci. (Med.), Leading Research Fellow, Department of Cardiosurgery
111a, Kievskaya str., Tomsk, 634012, Russian Federation
V. F. Mordovin
Cardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences
Russian Federation
Russian Federation
Dr. Sci. (Med.), Professor, Head of the Department of Arterial Hypertension
111a, Kievskaya str., Tomsk, 634012, Russian Federation
References
1. Achouh P., Isselmou K. O., Boutekadjirt R., D’Alessandro C., Pagny G. Y., Fouquet R., Fabiani J. N., Acar C. Reappraisal of a 20-year experience with the radial artery as a conduit for coronary bypass grafting. Eur. J. Cardiothorac. Surg. 2012; 41(1): 87–92.
2. Ruttmann E., Fischler N., Sakic A., Alber H., Chevtchik O., Schistek R., Ulmer H., Grimm M. Second internal thoracic artery versus radial artery in coronary artery bypass grafting: a longterm, propensity score-matched follow-up study. Circulation. 2011; 124(12): 1321–1329.
3. He G. W., Yang C. Q., Starr A. Overview of the nature of vasoconstriction in arterial grafts for coronary surgery. Ann. Thorac. Surg. 1995: 59: 676–683.
4. Friedman D. T., Pettersson G., Smedira N. G., Li J., Ellis S. G. Radial artery bypass grafts have an increased occurrence of angiographically severe stenosis and occlusion compared with left internal mammary arteries and saphenous vein grafts. Circulation. 2004; 109: 2086–2091.
5. Acar C., Jebara V. A., Portoghese M., Beyssen B., Pagny J. Y., Grare P., Chachques J. C., Fabiani J. N., Deloche A., Guermonprez J. L. Revival of the radial artery for coronary artery bypass grafting. Ann. Thorac. Surg. 1992; 54: 652–660.
6. He G. W., Yang C. Q. Radial artery has higher receptor-mediated contractility but similar endothelial function compared with mammary artery. Ann. Thorac. Surg. 1997; 63: 1346–1352.
7. Maniar H. S., Sundt T. M., Barner H. B., Prasad S. M., Peterson L., Absi T., Moustakidis P. Effect of target stenosis and location on radial artery graft patency. J. Thorac. Cardiovasc. Surg. 2002; 123: 45–52.
8. Ali E., Saso S., Ahmed K., Athanasiou T. When harvested for coronary artery bypass graft surgery, does a skeletonized or pedicled radial artery improve conduit patency. Interact. Cardiovasc. Thorac. Surg. 2010; 10(2): 289–292.
9. Miyagi N., Oshima N., Shirai T., Sunamori M. Skeletonised harvesting improves early-term and mid-term perfect patency of a radial artery graft. Jpn J. Thorac. Cardiovasc. Surg. 2006; 54: 472–476.
10. Attaran S., John L., El-Gamel A. Clinical and potential use of pharmacological agents to reduce radial artery spasm in coronary artery surgery. Ann. Thorac. Surg. 2008; 85(4): 1483–1489.
11. Shipulin V. M., Kozlov B. N., Korovin N. V., Afanasiev S. A. Intraoperative preparation of the radial artery for coronary artery bypass grafting. Angiology and Vascular Surgery. 2005; 2: 122–129.
12. Vecherskiĭ Yu. Y.u, Andreev S. L., Murashev B. Yu. New aspects of using dihydropyridine calcium antagonists during coronary bypass surgery. Ter. Arkh. 2010; 82(12): 19–22.
13. Moens A. L., Goovaerts I., Claeys M. J., Vrints C. J. Flow-Mediated Vasodilation A Diagnostic Instrument, or an Experimental Tool? Chest. 2005; 127: 2254–2263.
14. Inoue T., Matsuoka H., Higashi Y., Ueda S., Sata M., Shimada K. E., Ishibashi Y., Node K. Flow-mediated vasodilation as a diagnostic modality for vascular failure. Hypertens. Res. 2008; 31(12): 2105–2113.
15. Ding Y., Vaziri N. D. Nifedipine and diltiazem but not verapamil up-regulate endothelial nitric-oxide synthase expression. J. Pharmacol. Exp. Ther. 2000; 292: 606–609.
16. Kohonen M., Teerenhovi O., Terho T., Laurikka J., Tarkka M. Is the Allen test reliable enough? Eur. J. Cardiothorac. Surg. 2007; 32(6): 902–905.
17. Yokoyama N., Takeshita S., Ochiai M., Hoshino S., Koyama Y., Oshima A., Isshiki T., Sato T. Direct assessment of palmar circulation before transradial coronary intervention by color Doppler ultrasonography. Am. J. Cardiol. 2000; 86: 218–221.
18. Afanasiev S. A., Ripp T. M., Kozlov B. N., Kondratieva D. S., Mordovin V. F., Shipulin V. M. Method of the noninvasive assessment of functional competence of the radial artery for use as a vascular graft during performing coronary bypass operations. Patent for an invention RUS 2421139 24.06.2009.
19. Leluk V. G., Leluk S. E. Ultrasonic Angiology. Moscow: Medicine Press; 2003: 121–124.
20. Balakhonova T. V., Pogorelova O. A., Alidzhanova Kh. G., Soboleva G. N., At’kov O. Y. Noninvasive investigation of endothelial function in patients with hypertension and hypercholesterolemia (HCE). Ter. Arkh. 1998; 70(4): 15–19.
21. Kondrat’eva D. S., Afanas’ev S. A., Evtushenko A. V., Evtushenko V. V., Shipulin V. M. Сhronotropic and inotropic dependence of the myocardium in patients with rheumatic heart disease before and after amiodarone treatment. Fiziol. Cheloveka. 2008; 34(1): 52–56.
22. Zhen W., Tong H., Wang Y., Sun Y., Huang W., Ma Y., Tian J., Wu L. Coronary bypass revascularization with radial artery and internal mammary artery grafts. Chin. Med. J. 2002; 115(1): 55–57.
23. Atkov O. Y., Balahonova T. V., Pogorelova O. A. Non-invasive ultrasound detection of endothelial dysfunction. Eur. J. Ultrasound. 1998; 7(1): 37–45.
24. Bokeriia L. A., Sigaev I. Iu., Katsiia G. V., Berishvili I. I., Piskun A. V., Buziashvili Iu. I., Alekian B. G., Chigogidze N. A. Results of hospital bypass angiography in patients with coronary artery disease undergoing arterial and vein myocardial revascularization. Angiol. Sosud Khir. 2003; 9(2): 32–38.
25. Carpentier A., Guermonprez J. L., Deloche A., Frechette C., Du-Bost C. The aorta-to-coronary radial artery bypass graft. A technique avoiding pathological changes in grafts. Ann. Thorac. Surg. 1973; 16: 111–112.
26. Nakayama N., Ikezono K., Ohura M., Yabuuchi Y. Effects of the new long-acting dihydropyridine calcium antagonist pranidipine on the endothelium-dependent relaxation in isolated rat aorta in vitro. Arzneimittelforschung. 1993; 43(12): 1266–1270.
27. Luscher T. F. Endothelial dysfunction as a therapeutic target. The ENCORE trials. Eur. Heart J. 2000; 2 (Suppl D): 20–25.
28. Taddei S., Virdis A., Ghiadoni L., Uleri S., Magagna A., Salvetti S. Lacidipine restores endothelium-dependent vasodilation in essential hypertensive patients. Hypertension. 1997; 30: 1606–1612.
29. Vaziri N. D., Rodríguez-Iturbe B. Mechanisms of Disease: oxidative stress and inflammation in the pathogenesis of hypertension. Nature Clinical Practice Nephrology. 2006; 2(10): 582–593.
30. Berkels R., Taubert D., Bartels H., Breitenbach T., Klaus W., Roesen R. Amlodipine increases endothelial nitric oxide by dual mechanisms. Pharmacology. 2004; 70: 39‑45.
31. Cominacini L., Pasini A. F., Pastorino A. M., Garbin V., Davoli A., Rigoni A., Campagnola M., Tosetti M. L., Rosato P., Gaviraghi G. Comparative effects of different dihydropyridines on the expression of adhesion molecules induced by TNF-alpha on endothelial cells. J. Hypertens. 1999; 17: 1837–1841.
32. Ishii N., Matsumura T., Shimoda S., Araki E. Anti-atherosclerotic potential of dihydropyridine calcium channel blockers. J. Atheroscler. Thromb. 2012; 19(8): 693–704.
Review
For citations:
Ripp T.M., Kondratieva D.S., Afanasiev S.A., Muslimova E.F., Kozlov B.N., Mordovin V.F. FUNCTIONAL RECOVERY OF RADIAL ARTERY CONDUIT FOR CORONARY ARTERY BYPASS GRAFTING. Siberian Journal of Clinical and Experimental Medicine. 2018;33(3):30-35. https://doi.org/10.29001/2073-8552-2018-33-3-30-35
Views:
641
.png)
Email this article 