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CALCULATOR OF NON-OBSTRUCTIVE CORONARY ATHEROSCLEROSIS: CLINICAL CASE OF A MALE PATIENT WITH SUSPECTED CORONARY ARTERY DISEASE

https://doi.org/10.29001/2073-8552-2018-33-3-93-101

Abstract

Evidence suggests that most myocardial infarctions result from ruptures of the atherosclerotic plaques that do not significantly compromise coronary lumen before the event. However, detection of nonsignificant coronary lesions in patients with suspected coronary artery disease without coronary angiography is challenging. We developed a calculator for nonobstructive coronary atherosclerosis based on patient gender, age, and the presence or absence of the echocardiographic signs of ascending aorta atherosclerosis and arterial hypertension. The calculator may be used for determining the probability of non-obstructive coronary atherosclerosis and for promoting compliance of patients to lipid-lowering therapy.

About the Authors

E. I. Yaroslavskaya
Tyumen Cardiology Research Center, Tomsk National Research Medical Center
Russian Federation

Dr. Sci. (Med.), Professor, Leading Scientific Researcher, Laboratory of Instrumental Diagnostics of Scientific Division of Instrumental Research Methods

111, Melnikaite str., Tyumen, 625026, Russian Federation



V. A. Kuznetsov
Tyumen Cardiology Research Center, Tomsk National Research Medical Center
Russian Federation

Dr. Sci. (Med.), Professor, Head of Scientific Division of Instrumental Research Methods, Leader of Laboratory of Instrumental Diagnostics

111, Melnikaite str., Tyumen, 625026, Russian Federation



E. A. Gorbatenko
Tyumen Cardiology Research Center, Tomsk National Research Medical Center
Russian Federation

Laboratory Assistant and Researcher, Laboratory of Instrumental Diagnostics of Scientific Division of Instrumental Research Methods

111, Melnikaite str., Tyumen, 625026, Russian Federation



S. M. Dyachkov
Tyumen Cardiology Research Center, Tomsk National Research Medical Center Tyumen State University, Institute of Mathematics and Computer Sciences
Russian Federation

Junior Scientific Researcher, Laboratory of Instrumental Diagnostics of Scientific Division of Instrumental Research Methods

Graduate Student of the Department of Algebra and Mathematical Logic

111, Melnikaite str., Tyumen, 625026, Russian Federation

6, Volodarskogo str., Tyumen, 625003, Russian Federation



References

1. The World Health Organization the top ten causes of death fact sheet. Available at: http://www.who.int/mediacentre/factsheets/fs310/en/ (28 May 2018).

2. Efimova E. V., Konobeevskaya I. N., Boroda A. M., Karpov R. S. Gender aspects of cardiovascular mortality and population size of typical Western Siberia town. Sibirskij Meditsinskij Zhurnal. 2016; 31(3): 80–86 (In Russ).

3. Oshchepkova E. V., Efremova Yu. E., Karpov Yu. A. Morbidity and mortality from myocardial infarction in Russian Federation in 2000-2011. Terapevticheskij arhiv. 2013; 4: 4–10 (In Russ).

4. Little W. C., Constantinescu M., Applegate R. J., Kutcher M. A., Burrows M. T., Kahl F. R., Santamore W. P. Can arteriography predict the site of a subsequent myocardial infarction in patients with mild-to-moderate coronary artery disease? Circulation. 1988; 78: 1157–1166.

5. Aronov D. M., Ahmedzhanov N. M., Balakhonova T. V., Boytsov S. A., Bubnova M. G., Villeval’de S. V., Volkova S. G., Gornyakova N. B., Gratsianskiĭ N. A., Drapkina O. M., Zubareva M. Yu., Kobalava Zh. D., Konovalov G. A., Konstantinov V. O., Kuharchuk V. V., Martynov A. I., Martsevich S. Yu., Matchin Yu. G., Nikitin Yu. P., Perova N. V., Pokrovskiy S. N., Simonova G. I., Sinitsin V. E., Susekov A. V., Titov V. N., Chazova I. E., Shalaev S. V., Shal’nova S. A., Shcherbakova M. Yu. Diagnosis and correction of lipid metabolism disorders in order to prevent and treat atherosclerosis. Russian recommendations of the Russian National Society of Cardiologists (IV revision). Kardiovaskulyarnaya Terapiya i Profilaktika. 2009; 8(6), Suppl 3: 58 (In Russ).

6. Catapano A. L., Graham I., De Backer G., Wiklund O., Chapman M. J., Drexel H., Hoes A. W., Jennings C. S., Landmesser U., Pedersen T. R., Reiner Ž., Riccardi G., Taskinen M. R., Tokgozoglu L., Verschuren W. M. M., Vlachopoulos C., Wood D. A., Zamorano J. L., Cooney M. T.; ESC Scientific Document Group. 2016 ESC/EAS Guidelines for the Management of Dyslipidaemias. The Task Force for the Management of Dyslipidaemias of the European Society of Cardiology (ESC) and European Atherosclerosis Society (EAS). Eur. Heart J. 2016; 37(39): 2999–3058. DOI: 10.1093/eurheartj/ehw272.

7. Kuznetsov V. A., Yaroslavskaya E. I., Zyryanov I. P., Kolunin G. V., Krinochkin D. V., Gorbatenko E. A., Shurkevich N. P., Varshavchik M. V. Comparative profile of coronary artery disease patients of elder age and middle-aged without obstructive coronary stenosis. Serdtse. 2010; 9(3): 150–155 (In Russ).

8. Kuznetsov V. A., Yaroslavskaya E. I., Zyryanov I. P., Krinochkin D. V., Kolunin G. V., Gorbatenko E. A. Patent for invention No. 2553942 «A method for diagnosing non-obstructive coronary atherosclerosis in patients with suspected coronary artery disease», registered in the State Inventory of the Russian Federation 25.05.2015 (In Russ).

9. Kuznetsov V. A., Yaroslavskaya E. I., Dyachkov S. M., Gorbatenko E. A. Certificate of state registration of the computer program No. 2015661823 Calculator for determining the risk of nonobstructive coronary atherosclerosis in a patient with suspected coronary heart disease «ATHEROSCLEROSIS», registered in the Register of Computer Programs 09.11.2015 (In Russ).

10. Galiuto L. Badano K., Fox K., Sicari R., Zamorano J. L. The EAE textbook of Echocardiography. European Society of Cardiology. 2011: 477.

11. Touboul P. J., Hennerici M. G., Meairs S., Adams H., Amarenco P., Desvarieux M., Ebrahim S., Fatar M., Hernandez Hernandez R., Kownator S., Prati P., Rundek T., Taylor A., Bornstein N., Csiba L., Vicaut E., Woo K. S., Zannad F.; Advisory Board of the 3rd Watching the Risk Symposium 2004, 13th European Stroke Conference. Mannheim intima-media thickness consensus. Cerebrovasc. Dis. 2004; 18: 346–349.

12. Yusuf S., Hawken S., Ôunpuu S., Dans T., Avezum A., Lanas F., Mc-Queen M., Budaj A., Pais P., Varigos J., Lisheng L.; INTERHEART Study Investigators. Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study. Lancet. 2004; 364: 937–952.

13. Sachdeva A., Cannon C. P., Deedwania P. C., Labresh K. A., Smith S. C. Jr, Dai D., Hernandez A., Fonarow G. C. Lipid levels in patients hospitalized with coronary artery disease: an analysis of 136,905 hospitalizations in Get with the Guidelines. Am. Heart J. 2009; 157(1): 111–117. DOI: 10.1016/j.ahj.2008.08.010.

14. Mc Dermott M. M., Mandapat A. L., Moates A., Albay M., Chiou E., Celic L., Greenland P. Knowledge and attitudes regarding cardiovascular disease risk and prevention in patients with coronary or peripheral arterial disease. Arch. Intern. Med. 2003; 163: 2157–2162.


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For citations:


Yaroslavskaya E.I., Kuznetsov V.A., Gorbatenko E.A., Dyachkov S.M. CALCULATOR OF NON-OBSTRUCTIVE CORONARY ATHEROSCLEROSIS: CLINICAL CASE OF A MALE PATIENT WITH SUSPECTED CORONARY ARTERY DISEASE. Siberian Journal of Clinical and Experimental Medicine. 2018;33(3):93-101. (In Russ.) https://doi.org/10.29001/2073-8552-2018-33-3-93-101

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ISSN 2713-2927 (Print)
ISSN 2713-265X (Online)