COMPARISON OF MANUAL THROMBUS ASPIRATION WITH DIRECT STENTING IN PATIENTS WITH ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION AND TOTALLY OCCLUDED CULPRIT ARTERIES
https://doi.org/10.29001/2073-8552-2018-33-4-62-68
Abstract
The aim of this study was to evaluate the efficacy and safety of the manual thrombus aspiration in comparison with direct stenting in patients with ST-segment elevation myocardial infarction (STEMI) and totally occluded culprit arteries.
Material and Methods. Data were collected from the hospital database, which contained information about 1297 patients with STEMI who were admitted to the coronary care unit and underwent primary percutaneous coronary interventions. A total of 227 patients with totally occluded culprit arteries and partially or completely restored blood flow after wiring were included in the analysis. Altogether 25 patients after manual thrombus aspiration were compared with 202 patients after direct stenting. The groups were comparable by gender and age, and by the main clinical and angiographic characteristics.
Results. There were no differences in in-hospital outcomes. In the thrombus aspiration group, the rate of no-reflow phenomenon was higher insignificantly (8 vs 3.5%, р=0.259). There were no incidences of death and major adverse cardiac events in the thrombus aspiration group. No cases of stent thrombosis were registered in either of group.
Conclusion. The manual thrombus aspiration strategy in comparison with direct stenting in patients with STEMI and totally occluded culprit artery was not associated with improved clinical and procedural in-hospital outcomes.
About the Authors
I. S. BessonovRussian Federation
Cand. Sci. (Med.), Research Associate of the Scientific Department of Instrumental Research Methods, Interventional Cardiologist of the Department of X-ray Surgical Methods for Diagnosis and Treatment of Cardiovascular Diseases No. 1
111, Melnikaite str., Tyumen, 625026, Russian Federation
V. A. Kuznetsov
Russian Federation
Dr. Sci. (Med.), Professor of Cardiology, Honored Scientist of the Russian Federation, Head of the Scientific Department of Instrumental Research Methods, Deputy Director for Science
111, Melnikaite str., Tyumen, 625026, Russian Federation
I. P. Zyrianov
Russian Federation
Cand. Sci. (Med.), Head of the Department of X-ray Surgical Methods for Diagnosis and Treatment of Cardiovascular Diseases No. 1, Deputy Director for Scientific and Medical Work
111, Melnikaite str., Tyumen, 625026, Russian Federation
S. S. Sapozhnikov
Russian Federation
Interventional Cardiologist of the Department of X-ray Surgical Methods for Diagnosis and Treatment of Cardiovascular Diseases No. 1
111, Melnikaite str., Tyumen, 625026, Russian Federation
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Review
For citations:
Bessonov I.S., Kuznetsov V.A., Zyrianov I.P., Sapozhnikov S.S. COMPARISON OF MANUAL THROMBUS ASPIRATION WITH DIRECT STENTING IN PATIENTS WITH ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION AND TOTALLY OCCLUDED CULPRIT ARTERIES. Siberian Journal of Clinical and Experimental Medicine. 2018;33(4):62-68. (In Russ.) https://doi.org/10.29001/2073-8552-2018-33-4-62-68