Using the buccal graft (buccal mucosa) for arterioplasty of great vessels
https://doi.org/10.29001/2073-8552-2021-36-1-150-157
Abstract
Aim. The aim of this study was to develop and substantiate the possibility of using a buccal graft for arterioplasty of great vessels.
Material and Methods. The experiments were carried out using 48 animals including 45 mongrel rabbits weighing 5–7 kg and three dwarf pigs of the minipig breed weighing 35–45 kg. Vascular wall injury was modeled from the median laparotomy in all animals on the example of infrarenal abdominal aorta followed by plastic surgery of the vessel with a buccal graft. The animals were removed from the experiment in time-frame of up to 270 days.
Results. No stenoses, deformities, or aneurysmal extensions of the abdominal aorta were detected according to data of instrumental studies. The morphodynamic processes occurring in the buccal graft were characterized by the changes in the internal lining of autograft in the form of restructuring and acquisition of morphological traits of endothelial lining of the vessel and disappearance of the features intrinsic to the non-keratinized stratified squamous epithelium present in oral cavity.
Conclusions. The use of buccal graft as a material for arterioplasty of the great arteries demonstrated high efficiency in the follow-up period of up to 270 days. The use of this autograft was not associated with the development of arterial pseudoaneurysms in the arterioplasty area.
About the Authors
A. V. Gudkov
Siberian State Medical University
Russian Federation
Russian Federation
Dr. Sci. (Med.), Head of the Department of Urology
2, Moskovsky tract, Tomsk, 634050, Russian Federation
A. M. Idigov
Siberian State Medical University
Russian Federation
Russian Federation
Postgraduate Student, Department of Urology
2, Moskovsky tract, Tomsk, 634050, Russian Federation
B. N. Kozlov
Siberian State Medical University;
Cardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences
Russian Federation
Russian Federation
Dr. Sci. (Med.), Head of the Department of Cardiovascular Surgery; Professor,
Department of Hospital Surgery with the Course of Cardiovascular Surgery
2, Moskovsky tract, Tomsk, 634050, Russian Federation
111a, Kievskaya str., Tomsk, 634012, Russian Federation
References
1. Rerkasem K., Rothwell P.M. Patches of different types for carotid patch angioplasty. Cochrane Database Syst. Rev. 2010;2010(3):CD000071. DOI: 10.1002/14651858.CD000071.pub3.
2. Carrabba M., Madeddu P. Current strategies for the manufacture of small size tissue engineering vascular grafts. Front. Bioeng. Biotechnol. 2018;6:41. DOI: 10.3389/fbioe.2018.00041.
3. Chen F., Miwa S., Bando T., Date H. Pulmonary arterioplasty for the remaining arterial stump of the donor and the arterial cuff of the donor graft in living-donor lobar lung transplantation. Eur. J. Cardiothorac. Surg. 2012;42(5):e138–139. DOI: 10.1093/ejcts/ezs460.
4. De Martino A., Milano A.D., Bortolotti U. Use of pericardium for cardiac reconstruction procedures in acquired heart diseases – a comprehensive review. Thorac. Cardiovasc. Surg. 2019. DOI: 10.1055/s-0039-1697918.
5. Sarac T.P., Carnevale K., Smedira N., Tanquilut E., Augustinos P., Patel A. et al. In vivo and mechanical properties of peritoneum/fascia as a novel arterial substitute. J. Vasc. Surg. 2005;41(3):490–497. DOI: 10.1016/j.jvs.2004.11.033.
6. Fisher O., Meecham L., Buxton P., Legge J., Fairhead J., Rajagopalan S. et al. Long-term outcomes of bovine pericardial patch angioplasty for recurrent stenosis in vascular access: A UK single-centre experience. J. Vasc. Access. 2018;19(6):658–662. DOI: 10.1177/1129729818769795.
7. Mogaldea A., Theodoridis K., Goecke T., Tudorache I., Haverich A., Cebotari S. et al. Assessment of cytocompatibility and mechanical properties of detergent-decellularized ovine pericardial tissue. Int. J. Artif. Organs. 2019;42(11):628–635. DOI: 10.1177/0391398819850583.
8. Corno A.F., Smith P., Bezuska L., Mimic B. Is decellularized porcine small intestine sub-mucosa patch suitable for aortic arch repair? Front. Pediatr. 2018;6:149. DOI: 10.3389/fped.2018.00149.
9. Poncelet A.J., El Khoury G., De Kerchove L., Sluysmans T., Moniotte S., Momeni M. et al. Aortic valve repair in the paediatric population: Insights from a 38-year single-centre experience. Eur. J. Cardiothorac. Surg. 2017;51(1):43–49. DOI: 10.1093/ejcts/ezw259.
10. Badylak S., Geddes L., Geddes L., Obermiller J. Extracellular matrix for myocardial repair. Heart Surg. Forum. 2003;6(2):E20–26. DOI: 10.1532/hsf.917.
Review
For citations:
Gudkov A.V., Idigov A.M., Kozlov B.N. Using the buccal graft (buccal mucosa) for arterioplasty of great vessels. Siberian Journal of Clinical and Experimental Medicine. 2021;36(1):150-157. (In Russ.) https://doi.org/10.29001/2073-8552-2021-36-1-150-157
Views:
402
.png)
Email this article 