Combined interventional method of air-plasma flow and exogenous nitric oxide for the debridement of intracardiac infectious sites
https://doi.org/10.29001/2073-8552-2021-36-2-127-133
Abstract
Prosthetic valve endocarditis is a clinically severe pathology, which, unless timely treated, rapidly leads to the development of heart failure. The severity of the disease is caused by the fact that the microorganisms and toxins bypass biological barriers and constantly enter the bloodstream, which subsequently results in sepsis with the development of systemic embolism and multiple organ failure. The conservative antibiotic therapy is often ineffective due to the location of the infectious focus in the avascular zone. The operations for prosthetic infectious valve endocarditis are technically challenging and require high qualifications of the operating surgeon. The article presents a clinical case of surgical treatment for infectious prosthetic endocarditis of the aortic valve. The combined treatment with air-plasma flow and exogenous nitric oxide (NO) using the Plazon device without any antiseptic solutions was used as a method for the debridement of infectious site.
About the Authors
M. S. Kuznetsov
Cardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences; Siberian State Medical University
Russian Federation
Russian Federation
Mikhail S. Kuznetsov, Cand. Sci. (Med.), Senior Research Scientist, Department of Cardiovascular Surgery; Assistant Professor, Department of Hospital Surgery with the Course of Cardiovascular Surgery
111a, Kievskaya str., Tomsk, 634012, Russian Federation
2, Moscovsky tract, Tomsk, 634050, Russian Federation
G. G. Nasrashvili
Cardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences
Russian Federation
Russian Federation
Georgiy G. Nasrashvili, Cand. Sci. (Med.), Cardiovascular Surgeon, Department of Cardiovascular Surgery
111a, Kievskaya str., Tomsk, 634012, Russian Federation
D. S. Panfilov
Cardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences; Siberian State Medical University
Russian Federation
Russian Federation
Dmitriy S. Panfilov, Dr. Sci. (Med.), Cardiovascular Surgeon, Department of Cardiovascular Surgery; Assistant Professor, Department of Hospital Surgery with the Course of Cardiovascular Surgery
111a, Kievskaya str., Tomsk, 634012, Russian Federation
2, Moscovsky tract, Tomsk, 634050, Russian Federation
N. L. Afanasieva
Cardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences
Russian Federation
Russian Federation
Natalya L. Afanasieva, Cand. Sci. (Med.), Cardiologist, Department of Cardiovascular Surgery
111a, Kievskaya str., Tomsk, 634012, Russian Federation
B. N. Kozlov
Cardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences; Siberian State Medical University
Russian Federation
Russian Federation
Boris N. Kozlov, Dr. Sci. (Med.), Head of the Department of Cardiovascular Surgery; Professor, Department of Hospital Surgery with the Course of Cardiovascular Surgery
111a, Kievskaya str., Tomsk, 634012, Russian Federation
2, Moscovsky tract, Tomsk, 634050, Russian Federation
References
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Review
For citations:
Kuznetsov M.S., Nasrashvili G.G., Panfilov D.S., Afanasieva N.L., Kozlov B.N. Combined interventional method of air-plasma flow and exogenous nitric oxide for the debridement of intracardiac infectious sites. Siberian Journal of Clinical and Experimental Medicine. 2021;36(2):127-133. (In Russ.) https://doi.org/10.29001/2073-8552-2021-36-2-127-133
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