PRACTICAL RELEVANCE OF MAGNETIC RESONANCE IMAGING WITH PHARMACOLOGIC STRESS-TEST IN PATIENTS WITH ISCHEMIC HEART DISEASE SUBJECTED TO ENDOVASCULAR RECANALIZATION OF CHRONIC OCCLUSION OF THE RIGHT CORONARY ARTERY

The following research paper introduces the results of prospective randomized study comprising 72 patients with chronic total occlusion of the right coronary artery (RCA CTO). Participants were divided in 2 groups. All patients underwent cardiac magnetic resonance imaging (CMRI) with pharmacological stress-test for the evaluation of myocardial perfusion. Group 1 received endovascular recanalization of RCA CTO; group 2 received standard medical treatment. The follow-up examinations were performed at 2 and 12 months. All participants were evaluated as myocardium ischemia high risk patients (≥2 segments affected). After 2-month post randomization, statistically significant decrease in the number of segments with perfusion defects (-2.05 segments ranging from -2.58 to -1.52, 95% CI, р<0.001) and reduction in the number of high risk patients (from 39 (100.0%) to 29 (74.4%), р<0.001), were detected in group 1 compared with group 2. Neither of parameters in group 2 changed significantly at 1 year follow up. Therefore, according to CMRI data, PCI in patients with CTO RCA significantly reduced risk of myocardium ischemia; myocardial perfusion characteristics in patients without PCI remained unchanged.

магнитно-резонансная томография с фармакологическим стресс-тестом, перфузия миокарда, хроническая окклюзия правой коронарной артерии, дефект перфузии, ишемия миокарда, magnetic resonance imaging with pharmacologic stress-test in patients, myocardial perfusion, chronic occlusion of the right coronary artery, perfusion defect, myocardial ischemia

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