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Clinical case of severe aortic valve insufficiency due to ankylosing spondyloarthritis

https://doi.org/10.29001/2073-8552-2025-40-1-166-176

Abstract

Aortitis and aortic valve insufficiency are referred to as extraskeletal manifestations of ankylosing spondylitis (AS). Torpid course of diseases is the reason for late seeking medical care at the stage of irreversible changes and severe dysfunction of the cardiovascular and musculoskeletal systems. The article presents a clinical case of successful surgical treatment of severe aortic valve insufficiency in a patient with late diagnosed AS. The problems of cardiovascular pathology in AS, interdisciplinary interaction of doctors, choice of antirheumatic therapy and perioperative management of a very high cardiovascular risk patient with AS are discussed.

About the Authors

N. V. Rebrova
Cardiology Research Institute, Tomsk National Research Medical Centre, Russian Academy of Sciences, Tomsk, Russia (Cardiology Research Institute, Tomsk NRMC)
Russian Federation

Natalya V. Rebrova, Cand. Sci. (Med.), Head of the Department of Atherosclerosis and Coronary Artery Disease

111a, Kievskaya str., Tomsk, 634012



A. S. Krapivina
Cardiology Research Institute, Tomsk National Research Medical Centre, Russian Academy of Sciences, Tomsk, Russia (Cardiology Research Institute, Tomsk NRMC)
Russian Federation

Anastasia S. Krapivina, Laboratory Research Assistant, Department of Atherosclerosis and Coronary Artery Disease

111a, Kievskaya str., Tomsk, 634012



N. N. Sviazova
Cardiology Research Institute, Tomsk National Research Medical Centre, Russian Academy of Sciences, Tomsk, Russia (Cardiology Research Institute, Tomsk NRMC)
Russian Federation

Natalia N. Sviazova, Cand. Sci. (Med.), Ultrasound Diagnostics Doctor, Junior Research Scientist, Department of Atherosclerosis and Coronary Artery Disease

111a, Kievskaya str., Tomsk, 634012



N. V. Shcherban
Cardiology Research Institute, Tomsk National Research Medical Centre, Russian Academy of Sciences, Tomsk, Russia (Cardiology Research Institute, Tomsk NRMC)
Russian Federation

Natalya V. Shcherban, Radiologist of X-ray Computed Tomography Room, Department of Radiology and Tomography

111a, Kievskaya str., Tomsk, 634012



I. V. Stepanov
Cardiology Research Institute, Tomsk National Research Medical Centre, Russian Academy of Sciences, Tomsk, Russia (Cardiology Research Institute, Tomsk NRMC)
Russian Federation

Ivan V. Stepanov, Cand. Sci. (Med.), Head of the Pathoanatomical Department

111a, Kievskaya str., Tomsk, 634012



K. S. Likhomanov
Cardiology Research Institute, Tomsk National Research Medical Centre, Russian Academy of Sciences, Tomsk, Russia (Cardiology Research Institute, Tomsk NRMC)
Russian Federation

Konstantin S. Likhomanov, Cand. Sci. (Med.), Cardiologist, Department of Atherosclerosis and Chronic Coronary Heart Disease

111a, Kievskaya str., Tomsk, 634012



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For citations:


Rebrova N.V., Krapivina A.S., Sviazova N.N., Shcherban N.V., Stepanov I.V., Likhomanov K.S. Clinical case of severe aortic valve insufficiency due to ankylosing spondyloarthritis. Siberian Journal of Clinical and Experimental Medicine. 2025;40(1):166-176. (In Russ.) https://doi.org/10.29001/2073-8552-2025-40-1-166-176

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ISSN 2713-2927 (Print)
ISSN 2713-265X (Online)