Aortic root surgery in the beating heart: a case series
https://doi.org/10.29001/2073-8552-2025-40-2-159-167
Abstract
Aim: To describe the technique of surgical intervention on the aorta and aortic valve under working heart conditions with constant antegrade coronary myocardial perfusion and / or in combination with cardioplegic cardiac arrest; and also to assess the effectiveness of this method of myocardial protection and the possibility of its further use in aortic surgery.
Materials and methods: From March to November 2024, 12 patients underwent planned surgery at the S.G. Sukhanov Federal Center for Cardiovascular Surgery of the Ministry of Health of Russia (Perm). The average age was 57.75±9.8 years – 10 men (83.7%), 2 women (16.3%). All of them underwent off-pump aortic replacement: supracoronary aortic replacement (1 patient); supracoronary aortic replacement and aortic valve replacement (1 patient); supracoronary aortic replacement and coronary artery bypass grafting (CABG) using radiofrequency ablation (RFA) (1 patient); Bentall-De Bono procedure (1 patient); David procedure (7 patients). Two patients underwent surgical treatment through mini-J-sternotomy. One patient also underwent CABG. Among the patients, there were two with previous surgeries (CABG and MIDCAB). Two techniques were used: the first variant – full surgical intervention was performed on a beating heart using continuous antegrade coronary myocardial perfusion in 8 patients; the second variant – a combination of cardioplegic cardiac arrest with coronary myocardial perfusion on a beating heart – 4 patients.
During the study period, no patient died. Postoperative parameters (cardiac markers, electrocardiography (ECG), echocardiography) remained within normal limits. A number of complications were noted: one case of atrial fibrillation, terminated within the first day, one case of ventricular flutter intraoperatively with rhythm restoration after defibrillation, one case of mediastinal revision for hemostasis
Results. During the study period, no patient died. Postoperative parameters (cardiac markers, ECG, echocardiography(EchoCG)) remained normal. The following complications were noted: 1 case of atrial fibrillation, terminated within the first day, 1 case of ventricular fibrillation intraoperatively with rhythm restoration after defibrillation, 1 case of mediastinal revision for hemostasis.
Conclusion. Considering satisfactory intra- and postoperative data of surgical treatment of patients with aortic pathology on a beating heart with parallel cardiopulmonary bypass, as well as the absence of an increase in cardiac markers of myocardial damage in the perioperative period, we consider this technique applicable in surgical practice. Further development and use of the technique in aortic surgery on a beating heart using continuous antegrade coronary myocardial perfusion will reduce the myocardial stress during surgery, minimize the risks of postoperative complications and accelerate the patient's rehabilitation
About the Authors
A. V. MarchenkoRussian Federation
Andrey V. Marchenko, Dr. Sci. (Med.), Deputy Chief Medical Officer
35, Marshal Zhukov str., Perm, 614013
P. A. Myalyuk
Russian Federation
Pavel A. Myalyuk, Cand. Sci. (Med.), Doctor of Cardiovascular Surgery
35, Marshal Zhukov str., Perm, 614013
A. A. Petrishchev
Russian Federation
Alexey A. Petrishchev, Anesthesiologist-Resuscitator
35, Marshal Zhukov str., Perm, 614013
F. B. Samoshina
Russian Federation
Faina B. Samoshina, Medical Resident, Cardiovascular Surgeon
35, Marshal Zhukov str., Perm, 614013
A. A. Andrianova
Russian Federation
Anastasia A. Andrianova, Student
6-8, Lva Tolstogo str., St. Petersburg, 197022
V. A. Belov
Russian Federation
Vyacheslav A. Belov, Chief Physician
35, Marshal Zhukov str., Perm, 614013
References
1. Saushkin V.V., Varlamova Yu.V., Platonov A.S., Panfilov D.S., Stepanov I.V., Kozlov B.N., Sazonova S.I. Relationship between histomorphology and biomechanical properties of the ascending aortic wall in the aneurysm zone. Siberian Journal of Clinical and Experimental Medicine. 2024;39(3):96–104. https://doi.org/10.29001/2073-8552-2022-676
2. Pichugin V.V., Medvedev A.P., Gamzaev A.B., Chiginev V.A., Dobrotin S.S., Bodashkov M.V., Melnikov N.Yu. Valve replacement surgery in conditions of a “beating heart” as an alternative to the use of cardioplegia in patients with low myocardial reserve. Medical almanac. 2008;special issue:136–141. (In Russ.). EDN: JTXQNJ
3. Gorbachev V.I., Nadiradze Z.Z., Mikhailov A.V. Mechanisms of myocardial injury at open heart surgeries and methods of protection. Acta Biomedica Scientifica. 2006;5(51):56–62. (In Russ.). EDN: KZEXNJ
4. Lugovskaya N.M., Panfilov D.S., Maksimov A.I., Ponomarenko I.V., Svirko J.S., Podoksenov Yu.K. et al. Comprehensive lung protection during circulatory arrest in aortic arch surgery. Siberian Journal of Clinical and Experimental Medicine. 2021;36(1):108–116. https://doi.org/10.29001/2073-8552-2021-36-1-108-116
5. Salagaev G.I., Lysenko A.V., Lednev P.V., Belov Yu.V. Hemostatic measures in reconstructive aortic root surgery. Pirogov Russian Journal of Surgery. 2021;(11):83 87. (In Russ.). https://doi.org/10.17116/hirurgia202111183
6. S.F. Cicekcioglu F., Parlar A.I., Altinay L., Hijazi A., Irdem A.K., Katircioglu Beating heart mitral valve replacement in a patient with a previous Bentall operation. Gen. Thorac. Cardiovasc. Surg. 2008;56:226–228. https://doi.org/10.1007/s11748-007-0225-4
7. Skopin I.I., Ismagilova S.A. Simultaneous mitral/tricuspid valvular plasty on a beating heart through right-sided anterolateral thoracotomy following earlier cardiac interventions. Patologiya Krovoobrashcheniya i Kardiokhirurgiya. 2015;19(1):101–103 (In Russ). https://doi.org/10.21688/1681-3472-2015-1-101-103
8. Skopin I.I., Vavilov A.V., Merzlyakov V.Y., Latyshev M.S., Abadzhyan M.F., Slivneva I.V. Beating heart mitral valve replacement combined with minimally invasive myocardial revascularization in patient with acute ischemic mitral insufficiency type II. Cardiology and cardiovascular surgery. 2019;12(1):60–63. (In Russ). https://doi.org/10.17116/kardio20191201160
9. Babaroglu S., Yay K., Parlar A.I., Ates C., Mungan U., Cicekcioglu F. et al. Beating heart versus conventional mitral valve surgery. Interact. Cardiovasc. Thorac. Surg. 2011;12(3):441–447. https://doi.org/10.1510/icvts.2010.255240
10. Salerno T.A., Panos A.L., Tian G., Deslauriers R., Calcaterra D., Ricci M. Surgery for cardiac valves and aortic root without cardioplegic arrest (“beating heart”): experience with a new method of myocardial perfusion. J. Card. Surg. 2007;22(6):459–464. https://doi.org/10.1111/j.1540-8191.2007.00448.x
11. Mo A., Lin H. Surgical correction of ruptured aneurysms of the sinus of Valsalva using on-pump beating-heart technique. J. Cardiothorac. Surg. 2010;5(1):37. https://doi.org/10.1186/1749-8090-5-37
12. Ihnken K., Morita K., Buckberg G.D., Aharon A., Laks H., Beyersdorf F. et al. Simultaneous arterial and coronary sinus cardioplegic perfusion: an experimental and clinical study. Thorac. Cardiovasc. Surg. 1994;42(3):141–147. https://doi.org/10.1055/s-2007-1016476
13. Ihnken K., Morita K., Buckberg G.D., Aharon A., Laks H., Panos A.L. et al. The safety of simultaneous arterial and coronary sinus perfusion: experimental background and initial clinical results. J. Card. Surg. 1994;9(1):15–25. https://doi.org/10.1111/j.1540-8191.1994.tb00819.x
14. David T.E., Feindel C.M. An aortic valve-sparing operation for patients with aortic incompetence and aneurysm of the ascending aorta. J. Thorac. Cardiovasc. Surg. 1992;103(4):617–622. https://doi.org/10.1016/s00225223(19)34942-6
15. David T.E. Remodeling the aortic root and preservation of the native aortic valve. Operative Techniques in Cardiac and Thoracic Surgery. 1996;1(1):44–56. https://doi.org/10.1016/s1085-5637(07)70080-3
16. David T.E., Ivanov J., Armstrong S., Feindel C.M., Webb G.D. Aortic valve-sparing operations in patients with aneurysms of the aortic root or ascending aorta. Ann. Thorac. Surg. 2002;74(5):1758–1761. https://doi.org/10.1016/s0003-4975(02)04135-8
17. Komarov R.N., Katkov A.I., Puzenko D.V., Odinikova S.N., Nikolenko V.N. Surgery of the aortic root and aortic valve: history and modernity. Patologiya Krovoobrashcheniya i Kardiokhirurgiya. 2019;23(4):9–25. (In Russ.). http://dx.doi.org/10.21688/1681-3472-2019-4-9-25
Review
For citations:
Marchenko A.V., Myalyuk P.A., Petrishchev A.A., Samoshina F.B., Andrianova A.A., Belov V.A. Aortic root surgery in the beating heart: a case series. Siberian Journal of Clinical and Experimental Medicine. 2025;40(2):159-167. (In Russ.) https://doi.org/10.29001/2073-8552-2025-40-2-159-167