DAILY АRTERIAL STIFFNESS IN PATIENTS WITH BRONCHIAL ASTHMA, CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND «ASTHMA–CHRONIC OBSTRUCTIVE PULMONARY DISEASE» OVERLAP SYNDROME
https://doi.org/10.29001/2073-8552-2017-32-4-41-46
Abstract
Aim: to study changes in the parameters of the 24-hour arterial stiffness monitoring in patients with bronchial asthma, chronic obstructive pulmonary disease (СOPD) and asthma–COPD overlap syndrome. Material and Methods. 93 people were involved in the research: 50 patients with COPD, 28 patients with bronchial asthma, 15 patients with asthma–COPD overlap syndrome. The group of control included 24 practically healthy volunteers. Everyone underwent 24-hour blood pressure and arterial stiffness monitoring using BPLab MnSDP-2 monitor («Petr TELEGIN», Russia). Results. In patients with chronic diseases of the respiratory tract, there was a violation of the elastic properties of the arteries. In patients with COPD and asthma–COPD overlap syndrome, significantly higher Aix values were found in comparison with bronchial asthma and controls, and a violation of the daily profile of arterial stiffness was also noted. Patients with asthma and asthma–COPD overlap syndrome have higher (dP/dt)max values compared with patients with COPD and control group. Conclusion. In patients with bronchial asthma, COPD and asthma–COPD overlap syndrome is significantly higher arterial stiffness than in the control group
About the Authors
N. A. Karoli
Saratov State Medical University named after V. I. Razumovsky, Saratov
Russian Federation
Dr. Sci. (Med.), Professor of Hospital Therapy Department
Russian Federation
Dr. Sci. (Med.), Professor of Hospital Therapy Department
O. T. Zarmanbetova
Saratov State Medical University named after V. I. Razumovsky, Saratov
Russian Federation
Postgraduate, Hospital Therapy Department
Russian Federation
Postgraduate, Hospital Therapy Department
A. P. Rebrov
Saratov State Medical University named after V. I. Razumovsky, Saratov
Russian Federation
Dr. Sci. (Med.), Professor, Head of Hospital Therapy Department
Russian Federation
Dr. Sci. (Med.), Professor, Head of Hospital Therapy Department
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Review
For citations:
Karoli N.A., Zarmanbetova O.T., Rebrov A.P. DAILY АRTERIAL STIFFNESS IN PATIENTS WITH BRONCHIAL ASTHMA, CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND «ASTHMA–CHRONIC OBSTRUCTIVE PULMONARY DISEASE» OVERLAP SYNDROME. Siberian Journal of Clinical and Experimental Medicine. 2017;32(4):41-46. (In Russ.) https://doi.org/10.29001/2073-8552-2017-32-4-41-46
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